1,3 Dimethylamylamine is also known as DMAA, dimethylpentlamine, 1,3 dimeth, geranamine, and by several other names.
It is an incredibly potent organic compound and stimulant that is extracted from geraniums.
While it is more commonly used as a pre-workout supplement by athletes and bodybuilders, 1,3 Dimethylamylamine also has a wide range of nootropic effects that can improve mental performance.
Nootropic users have investigated whether or not this compound can be safely taken as a Smart Drug due to the intense energy rush and concentration it provides.
Interestingly enough, it was originally patented by the pharmaceutical company Eli Lilly for use as a nasal decongestant. It was re-introduced to the market as a nutritional supplement back in 2006 by a company named Proviant Technologies and was included in products such as Clear Shot and Amp.
Due to the risk of side effects, you should not use this supplement without speaking to a medical professional first.



- Neural stimulant similar to ephedrine
- Previously used in pre-workout supplements
- Banned by FDA in 2012 due to safety concerns
1, 3 Dimethylamylamine Effects:
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Although all of the mechanisms of action for this supplement are still not fully understood, there is general acceptance by experts and researchers that DMAA primarily acts to release the powerful neurotransmitter norepinephrine.
This is one of the adrenal neurotransmitters that controls our levels of attention, focus, energy, motivation and mental alertness.
The supplement is normally absorbed into the bloodstream through the intestinal tract and is then capable of crossing over the blood-brain barrier. This effectively allows entry into the central nervous system.
There is also some evidence to suggest that 1, 3 Dimethylamylamine stimulates the release of dopamine, another powerful mood enhancing neurotransmitter.
Dopamine is responsible for executive function related to focus and concentration as well as controlling movement and serving as part of our rewards system positive feedback loop.
1, 3 Dimethylamylamine Benefits:
DMAA is a central nervous system stimulant and there are a large number of potential benefits related to cognitive ability. Primarily, this means a considerable increase in energy and focus.
This can help many people from athletes and students, stay-at-home moms to workers in a professional setting. Additionally, DMAA has been known to heighten the senses and even lead to a sense of euphoria (probably due to the increased release of dopamine).
The supplement is especially useful for weight training athletes. Due to the increase in energy, it can be an excellent pre workout aid. The added focus and motivation can help lessen your tolerance to pain, improve your stamina and allow you to power through and complete intense training sessions.
An interesting benefit is vasoconstriction, meaning that it tends to restrict blood flow and is an effective method to stimulate muscle growth at a much lower level of intensity. Blood pressure will increase at a dose dependent rate, but without a corresponding increase in heart rate.
Due to the stimulant effects, this supplement may also be valuable for fat loss. This seems to have a thermogenic effect, raising the metabolism and enabling more efficient use and burning of fat. Studies have shown this supplement, when combined with caffeine and other typical commercial fat burner ingredients, to increase metabolic rate by 35% over a placebo.
1, 3 Dimethylamylamine Dosage:
The typically recommended DMAA dosage is between 25 and 75 mg. This can be taken up to several times a day, but generally only one daily administration is needed and recommended.
It is often used about 30 minutes before an intense study session or workout, or at any time when you think a shot of extra energy may come in handy.
The positive effects of this supplement last for a few hours, although people who do not experience an energy ‘crash’ may find this to last even longer.
1, 3 Dimethylamylamine Side Effects:
There have been a number of reports of side effects associated with this supplement. The most common of these is a noticeable lack of energy or ‘crash’ a few hours or so after taking DMAA. Of course, some people do not experience this at all. Additional side effects can include a significant increase in blood pressure. In extremely rare situations, it may also lead to an increased heart rate.
Most of the dangerous side effects which have been reported to the FDA are due to users taking much higher than recommended doses. Many of these users end up taking up to 500 or even 1,000 mg per day. Please do not exceed 25-75 mg at a time, and limit usage to no more than once or twice per day.
You should also not be combining 1, 3 Dimethylamylamine with other central nervous system stimulants or nootropics that have an effect on the adrenergic systems. Since this is a stimulant, it also may be a good idea to consider not using the supplement every day.
1, 3 Dimethylamylamine Review:
DMAA is powerful stimulant for short-term increases in mental energy and focus. It does, however, need to be used in strict accordance with the dosage recommendations outlined by the manufacturer.
It should not be used on a daily basis, but rather as part of a cycle, with periods of non-use in between periods of usage. Such a cycle could consider using something like Pramiracetam powder asa base supplement, and the DMAA only from time to time or in cases where energy demands are particularly high.
You may want to consider stacking it with L-Theanine or Sulbutiamine to prevent the any side effects related to anxiety, restlessness or jitters.
If taking DMAA as part of a nootropic stack for enhanced focus, it would be wise to combine it with Aniracetam, a choline source like Alpha GPC, and Picamilon to balance and synergize the positive effects.
Some people will find the stimulant effects of this compound to be too over-powering and not conducive to improving brain function. In certain cases, individuals have reported that the anxiety they experience when taking 1, 3 Dimethylamylamine makes it even harder to focus than when not using this supplement.
If you experiment with this drug and find that this applies to you, then you may want to consider looking at some of the different concentration-boosting nootropics available.
Some very good candidates include Noopept, Pramiracetam, Oxiracetam or the Alpha Brain nootropic stack.
Article last updated on: July 5th, 2018 by Nootriment
4 Comments
1,3 Dimethylamylamine (methylhexanamine) is not extracted from geraniums, but even if it was it wouldn’t matter. It’s still both illegal and dangerous.
From Wikipedia:
“Since 2006 methylhexanamine has been sold extensively under many names as a stimulant or energy-boosting dietary supplement under the claim that it is similar to certain compounds found in geraniums, but its safety has been questioned as a number of adverse events and at least 5 deaths have been associated with methylhexanamine-containing supplements. It is banned by many sports authorities and governmental agencies.”
“In April 2013, the US Food and Drug Administration determined that methylhexanamine was potentially dangerous and did not qualify as a legal dietary supplement; it warned supplement makers that it was illegal to market methylhexanamine and warned consumers of potentially serious health risks associated with methylhexanamine-containing products. The FDA has issued warning letters to manufacturers and distributors who continued to market products containing methylhexanamine.”
Hi Celeste,
Methylhexanamine (1,3 Dimethylamylamin, Geramanime, DMAA) is a component of some types of geranamines. This has been verified with high performance liquid chromatography and tandem mass spectrometry. http://www.la-press.com/analysis-and-confirmation-of-13-dmaa-and-14-dmaa-in-geranium-plants-us-article-a3413
Celeste apply cold water to the burned area :D
At “least” 5 deaths have resulted from driving automobiles, even by licensed drivers. You get my point. You can abuse ANYTHING and it can damage or kill you.