What do 7-Keto-DHEA reviews from users say about how this supplement works and are these claims backed up by research studies?
7-Keto-DHEA, also known as 3-acetyl-7-oxo-dehydroepiandrosterone, is a metabolite that is made from dehydroepiandrosterone (DHEA).
It is used for a number of purposes, including weight loss, muscle mass, fat reduction, energy production, men’s health and women’s health.
7-Keto-DHEA offers an alternative to DHEA supplements, which can cause hormonal side effects. While DHEA is needed for the production of androgens and estrogens, 7-Keto-DHEA does not break down into these hormones.
It has been shown to influence metabolism and thyroid function, which has led to studies on its potential use for fat loss.
Use of 7-Keto-DHEA as an oral supplement, is popular among bodybuilders and people interested in anti-aging and weight loss. Before taking this supplement, it is important to understand how it works and what types of effects it might have on the body.



- Increases thyroid hormone levels
- Boosts energy metabolism & fat loss
- Supports muscle growth & training
7-Keto-DHEA Review
Those who want to use 7-Keto-DHEA products should read user reviews beforehand to learn how this supplement has affected other individuals.
This helps consumers learn more about the effects and possible risks of these supplements.
Based on user testimonials posted online, one of the most common reasons for taking this supplement is to help individuals lose weigh and reduce body fat. This product has been beneficial as a weight loss aid for a relatively large number of consumers.
Many of those who take these products report that they have been able to lose weight and lower fat composition in addition to building lean body mass.
However, a small number of consumers who take these products have stated that they have not helped them lose fat or body weight.
A 2007 study in the Journal of Nutritional Biochemistry showed that 7-Keto-DHEA is able to increase resting metabolic rate in those who are on a calorie-restricted diet. [1]
An increase in metabolism might lead to more fat and calories burned, which can make it easier to lose weight.
A 2000 study in Current Therapeutic Research showed that taking 7-Keto-DHEA along with a weight-loss diet and resistance training regimen were more effective than just the diet and exercise program. [2]
In this study, participants taking the supplement lost 2.88kg of body weight over 8 weeks compared to 0.97kg for those on a placebo.
Review for Bodybuilding
7-Keto-DHEA is used as a supplement for building lean body or muscle mass and for increasing strength. Bodybuilders will typically take it during their “cutting” cycle to help them retain lean body mass while losing weight.
While it is associated with an increase in lean body mass, more research is needed to determine its efficacy for building muscle strength.
Regular DHEA supplements are typically used for building muscle strength and size due to their steroidal effects. This hormone precursor can increase activation of the androgen receptors and boost testosterone levels.
7-Keto-DHEA does not produce similar effects. It does not get converted into sex hormones in the body and does not activate androgen receptors. While one study showed that it could increase free testosterone levels in the blood, the effect was small.
Some consumers who take 7-Keto-DHEA for muscle mass indicate that these products are effective at increasing lean muscle mass while also reducing fat and overall body weight.
A relatively small number of consumers using this supplement for bodybuilding reported that these products did not help them increase lean muscle mass.
Men’s and Women’s Health
7-Keto-DHEA is used for improving cognition and general well-being in men and women. It is also used for stimulating the thyroid in those with low thyroid activity and improving immune function.
A moderate number of consumers who take these products for cognition reported improvements in concentration and memory, but other consumers stated that these products did not improve mental performance.
A 2000 study published in Steroids showed that 7-Keto-DHEA promoted slight improvements to memory in mice. [3] More research is needed to determine the efficacy of 7-Keto-DHEA for memory improvement in humans.
A small number of consumers who take 7-Keto-DHEA to improve thyroid function have reported that it is effective for this purpose, but a small number also indicated that 7-Keto-DHEA did not affect thyroid function.
A 2006 study in Physiological Research showed that 7-Keto-DHEA does increase the levels of T3 thyroid hormones in men. [4] It also produces similar results in women, but T3 increases in men and women are thought to be temporary.
While DHEA is used for erectile dysfunction, fertility and other men’s and women’s health conditions, 7-Keto-DHEA does not typically produce beneficial results for these conditions. It does not increase testosterone levels or affect estrogen levels as DHEA does.
7-Keto-DHEA pills are not approved as a drug by the FDA for the treatment, prevention or amelioration of any medical conditions.
Risks of 7-Keto-DHEA Use
7-Keto-DHEA does not typically lead to side effects related to hormone changes, such as oily skin and enlarged genitalia in women or breast tenderness and urinary urgency in men.
Most 7-Keto-DHEA reviews from consumers do not mention any hormonal side effects, although a very small number reported mood changes and other effects that might be linked to hormone changes.
It does have the potential to cause adverse reactions in those with thyroid problems. According to the University of Michigan Health System, 7-Keto-DHEA might cause increased levels of T3 hormones in the thyroid, which might raise the risk of harmful effects on the heart or lead to bone loss. [4]
If you have been diagnosed with thyroid problems or have a history of hyperthyroidism, it is important to consult a doctor before using 7-Keto-DHEA supplements.
The long-term effects of using 7-Keto-DHEA products are unknown. The University of Michigan Health System states that in research studies no adverse effects have been reported for those taking 200 MG daily for 8 weeks or less. [4]
Pregnant or nursing women should not take 7-Keto-DHEA supplements, since there is insufficient information on the safety of these products.
Before deciding to use this supplement to address a specific health goal, it is recommended to read more user reviews to understand how it has affected other individuals.
While you may not experience the same effects reported in 7-Keto-DHEA reviews posted by other users, it can help to learn about other people’s results.
- Zenk, J.L. et al. HUM5007, a novel combination of thermogenic compounds, and 3-acetyl-7-oxo-dehydroepiandrosterone: each increases the resting metabolic rate of overweight adults. Journal of Nutritional Biochemistry. 2007. Sep; 18(9); 629-34.
- Kaiman, D.S, et al. A randomized, double-blind, placebo-controlled study of 3-acetyl-7-oxo-dehydroepiandrosterone in healthy overweight adults. Current Therapeutic Research. 2000. Jul; 61(7); 435-442.
- Shi, J. et al. The effect of 7-oxo-DHEA acetate on memory in young and old C57BL/6 mice. Journal of Nutritional Biochemistry. 2000. Mar; 65(3); 124-9.
- Hampl, R. et al. how short-term transdermal treatment of men with 7-oxo-dehydroepiandrosterone influence thyroid function. Physiological Research. 2006. 55(1); 49-54.
- University of Michigan Health System. 7-Keto: Side Effects. 2015.
Article last updated on: July 9th, 2018 by Nootriment