Supplementation with AAKG 1250 Extreme Mega Caps may yield several significant health benefits. AAKG is more formally called arginine alpha ketoglutarate.
Arginine is a semi-conditional amino acid which is responsible for various vital biological functions. Alpha ketoglutarate is a ketone derivative of glutaric acid, which is an intermediary in the Kreb’s cycle.
Olimp AAKG Extreme Mega Caps is a dietary supplement that combines these two natural substances. According to the manufacturer, this product is “perfect for stimulating the growth of muscles and providing toughness and strength.”
It is promoted as a pre-workout strength booster that can increase nitric oxide levels, promote sexual performance, enhance lipolysis and thermogenesis while also enhancing muscle protein anabolism.
Although conclusive clinical evidence is currently lacking, the therapeutic uses of AAKG are believed to be wide ranging.
It is used by physicians, athletes and others who desire any of a variety of possible effects including increased muscular size and strength, reversing conditions like hypercholesterolemia and hypertension (high blood pressure), ensuring sufficient blood flow during surgical procedures and much more.



- Increases Nitric Oxide levels
- Improves nutrient delivery to muscles
- Boosts athletic performance
L-arginine in AAKG 1250
Related Topics
- Arginine Alpha-Ketoglutarate
- L-Arginine
- AAKG Supplements
- AAKG 1250 Extreme
- AAKG Side Effects
- L-Arginine Benefits
- Benefits for Men
- Benefits for Bodybuilding
- Effects on Blood Pressure
- Arginine Aspartate
- Arginine Pyroglutamate
- Arginine Ornithine and Lysine
- Suggested Dosages
- Food Sources
- Comparison to L-Citrulline
- Buy L-Arginine Powder
The amino acid, arginine, is one of the twenty most common amino acids known. It is integral for the survival of all DNA-based carbonic organisms; being one of the primary building blocks for messenger ribonucleic acid (mRNA).
It serves an array of functions in the body including:
- Protein synthesis and the prevention of muscular wasting;
- Increasing vasodilation via the synthesis of nitric oxide (NO);
- Healing wounds;
- Lowering blood pressure;
- Enhancing circulation;
The above list is just a small sampling of the potential and proven benefits of arginine. Research continues, testing L-arginine’s effectiveness in many human health scenarios.
It is under research for its effects on everything from breast cancer to heart disease, obesity to diabetes, infertility to inefficient cell signaling.
Our kidneys manufacture arginine, but if we require more, it must be gained via dietary sources including lean red meats, some fish, fowl, whole grains and green leafy vegetables.
Alpha Ketoglutarate in AAKG 1250
Alpha ketoglutarate is a simplistic substance that offers a double ketone bond of carbon and oxygen. It presents a negative charge and is known to be a vital constituent for the Kreb’s cycle.
The Kreb’s Cycle (aka Citric Acid Cycle, Tricarboxylic Acid Cycle) is the process of generating adenosine triphosphate, the body’s main energy source for all aspects of cellular metabolism.
AAKG 1250 is often used as a pre-workout supplement for this reason, as it is linked to higher energy levels and increased stamina.
AAKG 1250 and Vasodilation
Vasodilation occurs when the inner linings (endothelium) of circulatory blood vessels relax and open wider. That enables them to deliver more blood with equal, or less internal pressure.
As this increased blood flow courses throughout the body, it brings with it increased nutrients, oxygen, hormones and proteins. This is turn causes various health benefits associated with enhanced circulatory capacity.
For example, it can improve energy, mental alertness, removal of waste products, maintenance of cells and more.
L-arginine is used, in part, as a precursor to nitric oxide synthesis. When L-arginine is more available, NO is produced in greater amounts. Nitric oxide is a strong vasodilator.
Hence L-arginine supplementation is believed to help to accommodate more of the beneficial effects of consistent, generalized vasodilation.
AAKG and Muscle Development
Mounting clinical evidence continues to associate arginine alpha-ketoglutarate supplementation with increases in muscular size, power and stamina. In addition to the effects of vasodilation, AAKG supplementation is also known to bring on increased amounts of body insulin.
Insulin is an anabolic hormone that is released by the pancreas when the brain senses nutrient availability. It helps the body to absorb bioavailable nutrient sources, accommodating enhanced cellular functioning and regeneration.
The use of AAKG 1250 for bodybuilders is believed to deliver long-lasting muscular pumps, even hours after workouts. With the effects of generalized vasodilation present, the body continues to benefit.
Muscular performance is enhanced. Circulation is improved. Cellular metabolism becomes more efficient. Blood pressure is lowered and athletic strength training is generally heightened.
Enhancing Libido with AAKG 1250
Treating the symptoms of erectile dysfunction, infertility and low libido with AAKG 1250 may present benefits. Continuing clinical research suggests that that men who supplement with arginine alpha ketoglutarate are significantly more likely to achieve and maintain erections.
Further, sexual desire and performance stamina have been shown to increase. AAKG is also being tested for its possible capacity to reverse infertility in men and women.
Again, the effects of generalized vasodilation and nutrient absorption are key. As more blood, oxygen and glucose are delivered to the genetalia, associated sexual issues often diminish or reverse completely.
AAKG 1250 Safety and Possible Side Effects
As AAKG 1250 Extreme Mega Caps supplements are manufactured from combining two natural constituents, supplementation is generally very safe even when administered at therapeutic doses of 12 grams or more daily.
Only mild side effects are rarely reported. However, there are some groups of people who may be sensitive to elevated amounts of these natural substances.
The FDA has not received enough clinical evidence to make any firm recommendations for daily dosing. In all cases, it is always better to speak with your medical doctor about any supplementation you may be considering.
- Willoughby DS, Boucher T, Reid J, Skelton G, Clark M. Effects of 7 days of arginine-alpha-ketoglutarate supplementation on blood flow, plasma L-arginine, nitric oxide metabolites, and asymmetric dimethyl arginine after resistance exercise. Int J Sport Nutr Exerc Metab. 2011
- De Bandt JP, Cynober L, Lim SK, Coudray-Lucas C, Poupon R, Giboudeau J. Metabolism of ornithine, alpha-ketoglutarate and arginine in isolated perfused rat liver. Br J Nutr. 1995
- Wax B, Kavazis AN, Webb HE, Brown SP. Acute L-arginine alpha ketoglutarate supplementation fails to improve muscular performance in resistance trained and untrained men. J Int Soc Sports Nutr. 2012
- Le Boucher J, Coudray-Lucas C, Lasnier E, Jardel A, Ekindjian OG, Cynober LA. Enteral administration of ornithine alpha-ketoglutarate or arginine alpha-ketoglutarate: a comparative study of their effects on glutamine pools in burn-injured rats. Crit Care Med. 1997
- Riedel E, Hampl H, Steudle V, NĂ¼ndel M. Calcium alpha-ketoglutarate administration to malnourished hemodialysis patients improves plasma arginine concentrations. Miner Electrolyte Metab. 1996
Article last updated on: May 12th, 2018 by Nootriment
1 Comment
Can I combine whey protein and AAKG caps?