Alpha GPC is a Nootropic supplement which has been receiving a lot of attention recently.
Not only is it an effective brain booster and cognitive enhancer, but Alpha GPC benefits are thought to have long-term effects on your neurological systems.
This supplement may also promote better health of your neurons and may be able to protect and repair damaged cells. It may even improve the efficiency of communications between neurons within the brain.
The result is a boost to your memory, better learning and studying abilities, faster speed of thought, and increased mental clarity.
Furthermore, Alpha GPC has a very safe user profile and only mild side effects with very low toxicity.
What are some of the specific Alpha GPC benefits you can expect when taking this supplement and how does it work in the context of a nootropic stack?



- Choline source to support memory function
- Increases attention, focus & energy
- Neuroprotective for brain cell health
Alpha GPC Benefits on Memory
Related Topics
- Alpha Glycerylphosphorylcholine
- What is Choline?
- Alpha GPC Choline Content
- Health Benefits
- Dosages to Take
- User Reviews
- Side Effects
- Uses for Memory
- Effects on the Brain
- Increasing Growth Hormone
- Using Alpha GPC Powder
- Where to Buy Online
- Best Supplement Sources
- Comparison to CDP Choline
- Choline Alfoscerate
- Stacking with Piracetam
One of the first, and probably most desirable Alpha GPC benefits is that of memory improvement.
There is both academic research and anecdotal user reports and reviews that attest to this effect. Due to the increased levels of Acetylcholine associated with Alpha GPC, the processes related to memory formation become more efficient and you may find that you retain more of what you see, read, or hear during the day.
Acetylcholine is involved in both working memory capacity – short term memory that relates to fluid intelligence – as well as your long term memory storage – relating to crystallized intelligence.
When using Alpha GPC, some users may feel subtle changes like being able to remember long ago forgotten names and facts. Others might suddenly be able to recall all the dates and concepts from their high school history class, along with recall the details of every conversation they have ever held.
Overall speed of memory recall may also be improved for some.
The supplement also is able to increase the blood flow to the brain which results in better supply of nutrients for your brain cells. Specifically, Alpha GPC can increase oxygenation of the brain as well as cause more sugar to be metabolized for energy.
All of these Alpha GPC benefits combine to provide an increase in mental fuel which can improve attention span, focus, and concentration for many people.
Alpha GPC and Overall Brain Health
Alpha GPC benefits also show positive implications for maintaining overall brain health. Part of the reason behind this is the fact that the compound itself is a phospholipid, which is the same material that makes up cell membranes.
This supplement may help support the development of new and healthy cells and cell membranes while also repairing past damage.
Studies have shown that one of the reasons for cognitive decline related to aging is due to having a large number of neurons with worn out cell membranes. If there isn’t enough Choline in the diet, the body will auto-cannibalize the choline in cell membranes to make Acetylcholine. Alpha GPC can fix this problem, thereby improving the functioning and communication between brain neurons.
Alpha GPC powder also has anti-oxidant properties, serving to flush out toxins, poisons, and other harmful chemicals found in the brain and body.
The research on supplemental Choline is very promising so far, however more research is still needed, especially large-scale human trials. At this time, Alpha GPC is available as a health supplement only, and the FDA has not approved Alpha GPC as a drug to prevent or treat any conditions.
Alpha GPC Side Effects
While this supplement is considered safe and generally well tolerated, there are a few side effects which have been associated with Alpha GPC. However, these are very rare and generally mild, and for most people the Alpha GPC benefits outweigh the chance of some mild side effects.
There is no toxicity associated with Alpha GPC and no one has ever reported suffering from any type of dangerous or physically harmful overdose.
Most side effects are related to the dosage level. If someone exceeds the recommended dosage guidelines, they may suffer from headaches, fatigue, nervousness, nausea, diarrhea, or other GI issues. On some occasions this may include dizziness and lowered blood pressure.
Simply reducing the dosage back to the recommended levels or discontinuing use for a few days often relieves these negative effects.
Alpha GPC Stacks
Alpha GPC benefits do occur when the supplement is used on its own, but these effects are greatly amplified when it is taken with other nootropics.
In particular, Alpha GPC is considered one of the most efficient source of Choline that is commercially available today. As such, it works exceptionally well with Nootropics from the Racetam family, like Piracetam, or even Aniracetam or Oxiracetam.
These nootropic compounds work by increasing Acetylcholine receptiveness so when you pair this action with an acetylcholine precursor like Alpha GPC the results can be quite powerful.
Alpha GPC synergizes well with many other natural and synthetic nootropics and your imagination is really the only limit to designing the perfect stack for you.
- Antal A, Kéri S, Bodis-Wollner I. L-alpha-glycerylphosphorylcholine enhances the amplitude of the pattern electroretinogram in rhesus monkeys. A pilot study. Neurobiology (Bp). 1999
- Lopez CM, Govoni S, Battaini F, Bergamaschi S, Longoni A, Giaroni C, Trabucchi M. Effect of a new cognition enhancer, alpha-glycerylphosphorylcholine, on scopolamine-induced amnesia and brain acetylcholine. Pharmacol Biochem Behav. 1991
- TATTRIE NH, McARTHUR CS. The preparation of lecithin from L-alpha-glycerylphosphorylcholine. Can J Biochem Physiol. 1957
- Grasso S, Bramanti V, Tomassoni D, Bronzi D, Malfa G, Traini E, Napoli M, Renis M, Amenta F, Avola R. Effect of lipoic acid and ?-glyceryl-phosphoryl-choline on astroglial cell proliferation and differentiation in primary culture. J Neurosci Res. 2014
- Schettini G, Ventra C, Florio T, Grimaldi M, Meucci O, Scorziello A, Postiglione A, Marino A. Molecular mechanisms mediating the effects of L-alpha-glycerylphosphorylcholine, a new cognition-enhancing drug, on behavioral and biochemical parameters in young and aged rats. Pharmacol Biochem Behav. 1992
Article last updated on: March 13th, 2018 by Nootriment
2 Comments
I am having trouble downloading the free guide book. I entered my email and waited to see if it would come to my inbox, but it didn’t. Just wondering if it was still available.
Thanks So Much,
Stephanie Brunson
Hi Stephanie,
You can download the ebook at https://nootriment.com/NOOTRIMENT.COM%20-%20The%20Definitive%20Guide%20to%20120+%20Nootropic%20Supplements%20&%20Drugs.pdf
I hope that helps!