Alpha GPC is one of a handful of nootropics which should really be a part of every nootropic stack.
While some nootropic supplements are best for only specific goals, Alpha GPC Choline can help almost anyone improve their cognitive abilities.
This is because Alpha GPC powder is a derivative of choline, an essential nutrient in our diet necessary for boosting brain function. Not only is this a powerful supplement geared towards overall brain health, but it also has a number of cognitive enhancing benefits in its own right.
In fact, there is a lot of evidence to suggest that it actually complements and potentiates many other Nootropic supplements.
Before starting this type of supplementation routine, however, it is best to educate yourself fully on the mechanism of action for any supplement in question.
In this case, it would only be natural to examine what the promised benefits of Alpha GPC are. From there, it would be helpful to learn about which formulations might work best, which ones are the most cost effective, and some ideas and ways for finding a quality supplier.
You might particularly be wondering whether it is better to buy Alpha GPC powder or some of the pill or tablet versions of this supplement.



- Choline source to support memory function
- Increases attention, focus & energy
- Neuroprotective for brain cell health
Benefits Of Alpha GPC
Related Topics
- Alpha Glycerylphosphorylcholine
- What is Choline?
- Alpha GPC Choline Content
- Health Benefits
- Dosages to Take
- User Reviews
- Side Effects
- Uses for Memory
- Effects on the Brain
- Increasing Growth Hormone
- Using Alpha GPC Powder
- Where to Buy Online
- Best Supplement Sources
- Comparison to CDP Choline
- Choline Alfoscerate
- Stacking with Piracetam
When taking Alpha GPC supplements, users are likely to experience increases in their memory and learning capacity as primary benefits. In many cases, the speed of memory recall is also improved.
Blood flow to the brain, oxygen uptake, and even glucose metabolism are all improved as well. This will often lead to a fairly significant boost in both mental and even physical energy.
This boost can lead to feeling like someone is experiencing a high or a feeling of general well-being. Many users also see their attention spans expanded as well as improved abilities to focus and concentrate.
There are also a number of general brain health benefits for Alpha GPC powder. Since part of this compound has a phospholipid structure (and since this is the primary component of brain cell membranes), the supplement is critical in the synthesis of new cell membranes.
It also is helpful in the repair and restructuring of existing and damaged cells and cell membranes.
One of the symptoms associated with cognitive decline and Alzheimer’s (especially age related issues) is poorly maintained cell membranes. As such, it has been hypothesized that Alpha GPC supplements could play an important role in the future treatment of cognitive decline issues.
As these cells are repaired it also helps neurons to communicate with each better and function more efficiently.
Of course, the main benefit of Alpha GPC is that this compound is a precursor to Acetylcholine. Alpha GPC actually has a unique mechanism for increasing Acetylcholine levels compared to most choline sources including Citicoline.
While choline supplements are typically converted into Acetylcholine in the brain via certain enzymes, Alpha GPC actually naturally breaks down into Acetylcholine directly.
There are some that believe this is the most efficient source for Acetylcholine which is why Alpha GPC is currently favored among the many different choline sources out there.
If you are not familiar with the role of Acetylcholine in the brain, it would be a good idea to read up on this neurotransmitter so you understand just how important it is for the formation of new memories and connections between neurons.
Research on Alpha GPC is very promising, however more research is still needed to fully understand its effects. At this time, Alpha GPC is available as a health supplement only, and the FDA has not approved Alpha GPC as a drug to prevent or treat any conditions.
Alpha GPC Powder vs. Pills
A key decision to make with every supplement is which formulation to use.
Since Alpha GPC comes in powder and pills/capsules formulations, you might be wondering which is a better version to buy. Generally speaking, there are pros and cons to each form.
For pills, they are much more convenient and in a number of cases may even be easier to obtain. On the other hand, pills or capsules do take more time to become effective and to be absorbed into the bloodstream. The body actually first needs to dissolve and eliminate that coating of the pill or capsule.
In many cases, this can significantly slow down the time it takes the supplement to actually get to its destination and take effect.
Powders are ordinarily much faster acting. They do not need to undergo a ‘double’ assimilation. You will simply mix this with a drink like water, juice, or milk (although Alpha GPC is water soluble, so stay away from the milk with this one). Powder formulations get the supplement into the bloodstream more directly.
Additionally, you can custom tailor your dosage when you use powder. Capsules and tablets are available in set amounts (e.g. 100 mg, 500 mg), but with powder you can more easily customize your dosage for your personal needs.
On the other hand, it is certainly less convenient to have to take scoops of powder and mix it, then drink it.
Cheapest Alpha GPC Supplements
Another important factor is which form of Alpha GPC can be purchased for a cheaper price. This may be another reason to choose powders over pills and capsules.
The reason is that you can usually find powder formulations available in bulk at much lower costs. In fact, the packaging alone can contribute up to 80% of the cost of Alpha GPC supplements which is why the tablets are much more expensive than Alpha GPC powder.
Even if you would prefer to take your dosage as a pill, it is much cheaper to buy an inexpensive capping device and you can make your own capsules. This can also provide you full control over the dosage and allow you to pre-make your nootropic stacks by mixing ingredients.
Finding a quality supplier of Alpha GPC and other Nootropics will likely mean doing an online search. These supplements are growing in popularity but still have limited availability at traditional retailers.
Focus on companies that have received a fair number of customer and client reviews. Pay attention to how long they have been around since this is usually an indication of how they conduct themselves and treat their customers.
Also consider whether their prices for most supplements are similar to those charged by most other suppliers.
Overall, Alpha GPC choline powder is probably the better choice when looking at cost effectiveness and the speed of supplement absorption and action. Some may still prefer the convenience of taking pills or capsules. Ultimately, it really comes down to personal choice if you choose Alpha GPC powder or capsules.
- Plangár I, Szabó ER, T?kés T, Mán I, Brinyiczki K, Fekete G, Németh I, Ghyczy M, Boros M, Hideghéty K. Radio-neuroprotective effect of L-alpha-glycerylphosphorylcholine (GPC) in an experimental rat model. J Neurooncol. 2014
- Ricci A, Bronzetti E, Vega JA, Amenta F. Oral choline alfoscerate counteracts age-dependent loss of mossy fibres in the rat hippocampus. Mech Ageing Dev. 1992
- Tayebati SK, Tomassoni D, Nwankwo IE, Di Stefano A, Sozio P, Cerasa LS, Amenta F. Modulation of monoaminergic transporters by choline-containing phospholipids in rat brain. CNS Neurol Disord Drug Targets. 2013
- Bronzetti E, Felici L, Amenta F. Effect of ipsilateral lesioning of the nucleus basalis magnocellularis and of L-alpha-glyceryl phosphorylcholine treatment on choline acetyltransferase and acetylcholinesterase in the rat fronto-parietal cortex. Neurosci Lett. 1993
- Di Perri R, Coppola G, Ambrosio LA, Grasso A, Puca FM, Rizzo M. A multicentre trial to evaluate the efficacy and tolerability of alpha-glycerylphosphorylcholine versus cytosine diphosphocholine in patients with vascular dementia. J Int Med Res. 1991
- Govoni S, Battaini F, Lucchi L, Pascale A, Trabucchi M. PKC translocation in rat brain cortex is promoted in vivo and in vitro by alpha-glycerylphosphorylcholine, a cognition-enhancing drug. Ann N Y Acad Sci. 1993
- Amenta F, Del Valle M, Vega JA, Zaccheo D. Age-related structural changes in the rat cerebellar cortex: effect of choline alfoscerate treatment. Mech Ageing Dev. 1991
- OKUI S, SUZUKI Y, KOYAMA H, UMEZAWA O. [STUDIES ON THE HYDROLYSIS OF LECITHINE WITH HYDROXIDES OF ALKALINE EARTH METALS AND THE PREPARATION OF L-ALPHA-GLYCERYLPHOSPHORYLCHOLINE]. Yakugaku Zasshi. 1964
Article last updated on: March 13th, 2018 by Nootriment
1 Comment
Hola, vivo en la región metropolitana y quisiera saber cuál es mejor para cubrir necesidades cerebrales y energía física. Además, vivo en Santiago de Chile y no sé dónde adquirir el producto. Gracias.