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What is the best dosage of Aniracetam to take and how should you use this nootropic agent to get the best results?
Aniracetam is a fat-soluble member of the racetams family of nootropic drugs. It is thought to be at least two to three times more potent than the original nootropic, Piracetam.
As a therapeutic drug for the treatment of memory dysfunction, is typically used in dosages of between 750 mg to 1500 mg per day. However, research has been conducted on a wider range of dosages up to 4 grams per day.
Aniracetam doses has also proven to be very safe with only a limited number of mild side effects reported.
How should you use aniracetam and what is the best dose level? This article will answer those questions and give you more insights into taking an Aniracetam dosage. Buy Aniracetam online at this link.
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Aniracetam Dosage Guide
Related Topics
- What is Aniracetam?
- User Reviews
- Effects and Benefits
- Aniracetam for Anxiety
- Dosage Suggestions
- Using Aniracetam Powder
- Best Way to Take
- Side Effects
- Aniracetam for Sale
- Buyer's Guide
- Is Aniracetam Legal?
- Stacking with Piracetam
- Stacking with Choline
- Comparison to Piracetam
- Comparison to Oxiracetam
- Comparison to Pramiracetam
- Comparison to Noopept
The accepted dosage for clinical use of Aniracetam is between 750 mg and 1500 mg.
It has been used in lower dosages of 200 mg taken three times a day to treat anxiety and depression linked to cerebral infarction.
Some studies have examined its use in dosages of 3 to 4 grams per day. However, the majority of research observations have involved dosages of 750 mg, 1000 mg or 1500 mg daily.
Lower dosages may not produce desired effects. Higher dosages can result in diminishing return with a greater potential for side effects.
Aniracetam doses are typically repeated as often as every three hours. It has a short half-life of 1-2.5 hours, but is very fast acting.
It is fat-soluble, which means that it can be dissolved in fats or lipid molecules. This property means that it is better absorbed from the gastrointestinal tract after ingestion compared to water soluble racetams like Piracetam.
Many sources recommend taking it with food or using it alongside fish oil supplements or olive oil to optimize its absorption into your bloodstream.
To prevent insomnia or disturbances to your sleep pattern, avoid taking dosages of this nootropic before bed or late in the day. It is best used in the morning due to the stimulating effects it can have in some users.
Aniracetam is typically consumed as an oral capsule or in the form of a bulk powder that is mixed into a liquid solution like milk or orange juice.
Aniracetam has also been administered in animal and human research studies as an intravenous injection. It has been studied in dosages of 2mg, 10mg and 100 mg for IV therapy.
This usage is typically reserved for patients with cerebral ischemia, under hypoxic hypoxidosis or more serious forms of cognitive decline. There is no evidence suggesting that administration by IV is more effective than oral administration.
Megadose Effects
Some sources describe using an Aniracetam megadose, which is described as a high dosage greater than 3 grams per day.
Megadoses of between 5 – 10 grams have been described in user reviews online. Note that the practice of megadosing any nootropic agent has the potential to be dangerous and increases the likelihood of serious side effects ocurring.
One user who took 3 grams of Aniracetam followed by another 2 grams described it as causing insomnia, a mild psychadelic experience and changes in visual perception.
Another user who took 10 grams in one serving experienced mental “slowness”, calmness, a “chilled out” feeling and describe himself as feeling normal the following morning.
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Stacking with Other Nootropics
It is typical for nootropics to be used in stacks, as opposed to taking one ingredient at a time. This is not necessary to experience positive effects.
However, it is generally believed that better results can be achieved by taking combinations of synergistic ingredients.
If you stack Aniracetam with other nootropic supplements, you may need a smaller dosage of this compound to experience the benefits.
One stack that should be considered is the Aniracetam Choline Stack which combines this cholinergic racetam with a source of the dietary nutrient choline.
This nutrient is found in many foods including eggs, liver, fish, chicken, beef, some grains and broccoli. It is necessary for the brain to make the neurotransmitter acetylcholine, which is one of the main brain chemicals affected by Aniracetam.
The amount of choline to take will depend on the form of this supplement you are using. Some forms are more bioavailable and better able to cross over the blood-brain barrier.
Choline Bitartrate, Phosphatidylcholine, DMAE and Lecithin require higher dosages to experience any nootropic effects.
Cytidine diphosphate-choline (CDP Choline), Alpha-glycerophosphocholine (Alpha-GPC) and Centrophenoxine are good acetylcholine precursors that promote increased availability of this chemical messenger molecule.
If using Alpha GPC, the recommended dosage is 200 mg for every 750 mg of Aniracetam used. If taking CDP Choline, the recommendation is a ratio of 300 mg for every 750 mg per day.
You can find out more about the best dosages for your Aniracetam and Choline Stack here.
Additional nootropics and smart drugs that may be stacked include other racetams like Noopept, Oxiracetam, Piracetam, Pramiracetam, Phenylpiracetam, Coluracetam or Nefiracetam.
It has also been used with Adrafinil, Modafinil, Armodafinil, Phenibut, Picamilon, Sulbutiamine and Tianeptine.
It may be combined with natural nootropics as well including Bacopa Monnieri, L-Theanine, Phosphatidylserine, Huperzine A or Vinpocetine.
Check out our Complete Guide to Aniracetam Stacks here for more information.
Uses & Benefits
This nootropic is thought to promote creativity and holistic thinking, along with supporting an improve emotional state.
Users have reported that they feel more focused, more alert and have better memory performance when taking this compound.
Aniracetam has been used both clinically and for the enhancement of cognitive function in healthy adults. However, all of the human research studies have been conducted on its effects for ameliorating forms of cognitive deficit and not for improving mental performance under normal conditions.
Researchers have found it to be beneficial in the treatment of Alzheimer’s disease, senile dementia and memory loss that is associated with aging or brain degeneration.
It can affect systems in the brain involved in memory, information processing, synaptic plasticity, behavioral control, mood regulation as well as visual and auditory perception.
Aniracetam is a positive allosteric modulator of the AMPA subclass of glutamate receptors in the hippocampus and elsewhere in the brain. AMPA receptors play a role in Long-Term potentiation, which describes one of the mechanisms by which neurons form long-lasting connections and store our long-term memories.
This nootropic also enhances cholinergic neurotransmission by influencing acetylcholine release and modulating nicotinic receptors.
In some cases, Aniracetam has been used to address symptoms of depression. It is believed to increase levels of Dopamine and Serotonin release in certain parts of the brain.
User reviews of this nootropic cite benefits for learning, thinking more clearly, greater mental energy, alertness and an improved ability to focus and concentrate on tasks at hand.
Aniracetam is well-regarded among users to improve verbal and linguistic functioning. As verbal acuity improves, users have described feeling better able to explain complex concepts and articulate their thoughts with better vocabulary.
Based on anecdotal testimonials. it is considered beneficial for preparing for public speaking presentations, interviews, essay writing, debates, and social functions.
There is also an axiolytic effect, meaning it helps to inhibit mild feelings of anxiety in some people. It may produce feelings of confidence and greater ease in social settings.
Many of the purported benefits of taking Aniracetam capsules and powder are based on what users have said in reviews as opposed to scientific research. There is limited human research data available to form conclusions on.
More studied in humans are needed to understand the nootropic mechanisms and effects of this smart drug.
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Harmful Side Effects
Use of Aniracetam in clinical research studies does not typically produce adverse effects. In one study, the researchers reported that the “Tolerability of Aniracetam was excellent.”
The most commonly reported side effect is a headache, whcih can occur with all of the racetam nootropic supplements. It is believed that this may occur due to depletion of one of the neurotransmitters affected by Aniracetam.
The generally accepted wisdom is that adding a choline supplement to your stack can alleviate headaches for most users.
One of the interesting side effects of taking this nootropic is that it can lead to a loss of inhibitions. Combining it with alcohol can increase the intoxifying effects
Some users may also experience mild nausea, fatigue, brain fog, nervousness, agitation, delayed sleep onset, vertigo or diarrhea after taking a dosage.
In rare cases, skin rashes or allergic reactions can occur. Some people report more serious mood disturbances, changes in ability to focus, excessive sweating and increased body temperature.
Many users do not experience any side effects and, in those that do, symptoms typically shortly after discontinuing use. Reducing the dosage should be considered if any of these side effects become too bothersome or regular.
Individuals who have been diagnosed with kidney or liver disorders (such as renal insufficiency) may be required to take a smaller dosage of this nootropic agent. These medical conditions can impact how the drug is metabolized or cleared from the body.
Consult with a doctor before taking this cognitive enhancer if you have been diagnosed with any kind of medical condition or are currently using drugs to treat a health problem.
Dangers of High Dosages
Is there a risk of overdose from using too much Aniracetam powder? What are the side effects associated with high dosages?
There have not been any cases of overdose or dangerous side effects reported from taking excessive amounts of this nootropic drug.
High dosages can increase the risk of negative effects, but are not believed to threaten your long-term health and wellbeing.
In research studies on animals, this nootropic exhibits a very low potential for toxicity even at dosages many times the normal amount used to produce therapeutic effects.
It has an LD50 in rats of 4.5 grams/kg of bodyweight. The LD50 is the dosage required to kill 50% of the population. Typically, rats are given dosages of 10-100 mg/kg of bodyweight.
If you do take more than the recommended maximum dosage of 3 grams per day, you may experience a greater risk of headaches, decline in abiity to focus (brain fod), low energy or sleepiness, irritable mood, increased anxiety, insomnia, feeling flushed, nausea, loss of appetite and other mild stimulant-like effects.
It is recommended to stay within the dosage range of 750 mg to 1500 mg per day to minimize the risk of adverse effects. This dose is normally sufficient to experience the benefits and will not pose any danger to your health.
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- Tanaka Y, Kurasawa M, Nakamura K. Cholinergic and dopaminergic mechanisms involved in the recovery of circadian anticipation by aniracetam in aged rats. Pharmacol Biochem Behav. 2002
- Ouchi Y, Kakiuchi T, Okada H, Nishiyama S, Tsukada H. The effect of aniracetam on cerebral glucose metabolism in rats after lesioning of the basal forebrain measured by PET. J Neurol Sci. 1999
- Bartolini L, Casamenti F, Pepeu G. Aniracetam restores object recognition impaired by age, scopolamine, and nucleus basalis lesions. Pharmacol Biochem Behav. 1996
- Spignoli G, Pepeu G. Interactions between oxiracetam, aniracetam and scopolamine on behavior and brain acetylcholine. Pharmacol Biochem Behav. 1987
- Lee CR, Benfield P. Aniracetam. An overview of its pharmacodynamic and pharmacokinetic properties, and a review of its therapeutic potential in senile cognitive disorders. Drugs Aging. 1994
Article last updated on: March 13th, 2018 by Nootriment
2 Comments
Dosage? Will be answered in this aritcle? Well read it three times and I guess you need some aniracetam, because you totally forgot that.
Hello,
The dosage is discussed in this article – “between 750 mg and 1500 mg.” We also provide dosage information in the sidebar on the site for quick review.