Arcalion is the brand name for the supplement called Sulbutiamine that can dramatically increase mental energy.
It is a lipophilic (or fat-soluble) synthetic derivative of Vitamin B1 (Thiamine).
In some countries it is prescribed for a small number of medical conditions such as asthenia, a condition of chronic fatigue that has a neurological rather then a physical sources. However Arcalion is more commonly used as a supplement for cognitive enhancement purposes.
The mechanism of action for Arcalion 200 mg tablets is quite similar to the role that Thiamine plays in your brain, but with a much higher potency. Users who take Arcalion say that it increases their alertness, memory capacity, and focus, and boosts their mood without causing negative side effects.
Because Arcalion 200 mg pills manufactured by Serdia are fairly expensive, it has become more common to buy generic Sulbutiamine which is chemically identical but much cheaper.



- Heightened alertness, focus & energy
- Supports memory & mental performance
- Promotes mood through dopaminergic activity
Review of Arcalion 200 mg Tablets
Related Topics
- What is Sulbutiamine?
- What is Arcalion?
- User Reviews
- Effects and Benefits
- Why Take Sulbutiamine?
- Sulbutiamine for Energy
- Effects on Dopamine
- Dosage Guidelines
- Sulbutiamine for Anxiety
- Possible Side Effects
- Bulk Sulbutiamine Suppliers
- Buying Sulbutiamine Online
- Arcalion Uses
- How to Take Arcalion
- Is Arcalion Safe?
- Buy Arcalion
Within the brain, there are several different neurotransmitter systems that are used to control cognitive processes ranging from short-term memory, to learning, to the ability to pay attention.
Vitamin B1 or Thiamine is involved in all of these processes because it is used by your brain cells to make the energy molecule ATP (adenosine triphosphate).
The molecular design of Arcalion is basically two modified Thiamine molecules connected by a sulfur bond. This structure makes it better able to cross over into the brain as compared to Thiamine by itself.
Arcalion 200 mg tablets have the same net effect of increasing energy production in brain cells, but they are able to do so at a much smaller effective dose in contrast to taking Vitamin B1 supplements. This nootropic compound also has some unique properties not exhibited by simple Thiamine.
Because of this broad-based impact on cellular function, Arcalion is known to potentiate the cholinergic, glutamatergic and dopaminergic systems in the brain. For example, Arcalion has been shown to increase cholinergic activity, specifically in the hippocampus area of the brain.
This means that it causes greater enhancement of Acetylcholine neuroreceptors in memory storage faculties. This neurotransmitter is involved in working memory capacity as well as memory consolidation processes that encode information for long-term storage.
In studies on experimental animals, Arcalion-treated mice had better results on object recognition tests as well as operant conditioning tests. In research studies this drug has also been shown to improve memory-related function in early stage Alzheimer’s disease patients, especially when combined with acetylcholinesterase inhibitors like Huperzine A or Galantamine.
It is not surprising that researchers have investigated giving Arcalion 200 mg doses to Alzheimer’s subjects since this disease is precipitated by a substantial decline in cholinergic activity in the brain. Healthy individuals with no signs of Alzheimer’s have also seen improvements in their memory, clarity of thought, and comprehension ability when taking this cognitive enhancer.
It has even shown some use in treating memory issues in patients suffering from schizophrenia.
One of the clinical uses for this supplement is in treating a form of chronic fatigue known as asthenia. This mood disorder is related to depression and is characterized by the inability to feel excited as well as persistently low energy levels. In some studies, Arcalion has proven effective in improving this condition by restoring mental energy, motivation, feelings of pleasure and a positive mood.
Arcalion is also taken for cases of social anxiety or psycho behavioral inhibition. This condition is characterized by shyness, fearfulness, timidity, and guardedness surrounding new stimuli. This supplement is noted to help resolve such issues, especially in individuals with major depressive disorder.
Using Arcalion 200 mg tablets can also enhance stamina across both physical and mental domains. It is observed to have some stimulant qualities without actually being a stimulant itself. Some users say that the energy you receive is like a strong dose of caffeine except that there are no side effects like anxiety or restlessness.
Arcalion can help you to power through a long and hectic day of work, school, or even taking care of a home and family. Some athletes and bodybuilders used it to boost their athletic performance, saying that it improves their endurance and tolerance for pain. For anyone who seems to have that always tired or run down feeling, Arcalion may be helpful for improving energy levels.
Research on Sulbutiamine is promising, however current research is limited, and more studies need to be done to understand it’s full effects. While Arcalion is treated in some countries as a drug, in the USA it is available as a health supplement only, and the FDA has not approved Sulbutiamine as a drug to prevent or treat any conditions.
Where to Buy Arcalion 200 mg Tablets
If you are ready to give Arcalion a try, you might be wondering where you can find this supplement.
Unfortunately, in most countries around the world the brand name Arcalion tablets require a prescription to purchase at your local pharmacy. Due to a reluctance for prescribing so-called “lifestyle medications”, many doctors may be reluctant to write such a prescription.
However, the active ingredient from Arcalion is available to buy as a supplement called Sulbutiamine. Generic Sulbutiamine also tends to be about 1/6th the price of Arcalion on an equivalent dosage basis. To purchase Sulbutiamine tablets or powder, you can look online at suppliers such as Peak Nootropics.
Dosage Recommendations
Proper dosage us dependent on many factors and it is recommended that you speak with your doctor to determine the best dosage for your needs. The following dosage recommendations are general guidelines only, and your personal dosage may be different.
The standard dosage is to take two to three Arcalion 200 mg tablets per day. Some users have reported taking as much as 1000 mg in a single day without negative side effects, but you should start at the lower end of the scale. This will allow your body to adjust to the effects of the drug and will give you time to experiment with the best dosage.
Because it is fat-soluble, you should ideally take it with food to ensure as much of it as possible is absorbed into your bloodstream. Many users stack it with a Choline supplement like Alpha GPC as well as a Racetam supplement such as Aniracetam.
A common practice with Arcalion or Sulbutiamine is to take it only when you need a little extra energy. For example, instead of taking it every day you might only use it when preparing for a test or exam or before a big client presentation.
Another major reason to only take it occasionally is that it will prevent your body from developing a tolerance to the effects of 200 mg dosages of Arcalion. After weeks of consistent use, you may find that you need to constantly increase your dosage to get the same effects. Cycling or taking it irregularly will prevent this occurrence and allow you to enjoy the benefits of Arcalion 200 mg tablets more safely.
- Litvinovich EF, Langeman TI, Litvinovich SF. [The use of sulbuthiamine (enerion) in the combined therapy of patients with symptomatic focal epilepsy]. Zh Nevrol Psikhiatr Im S S Korsakova. 2006
- Kiew KK, Wan Mohamad WB, Ridzuan A, Mafauzy M. Effects of sulbutiamine on diabetic polyneuropathy: an open randomised controlled study in type 2 diabetics. Malays J Med Sci. 2002
- Tiev KP, Cabane J, Imbert JC. [Treatment of chronic postinfectious fatigue: randomized double-blind study of two doses of sulbutiamine (400-600 mg/day) versus placebo]. Rev Med Interne. 1999
- Bettendorff L. The compartmentation of phosphorylated thiamine derivatives in cultured neuroblastoma cells. Biochim Biophys Acta. 1994
Article last updated on: March 13th, 2018 by Nootriment