The Ashwagandha plant has been used in Indian Ayurvedic medicine for thousands of years.
Ashwagandha components found in its roots, leaves, and berries contain a variety of photochemicals and nutrients, include amino acids and choline.
It is considered one of the most beneficial and important herbs in the practice of Ayurveda- a form of alternative medicine utilizing natural components found in nature.
This traditional medicine utilizes a whole body approach to health and wellness and involves mind, body, and soul in its practices.
While regarded as safe for regular use, there are some Ashwagandha side effects that you should be aware of before purchasing this supplement.



- Reduces stress and anxiety
- Improves concentration, fatigue & sleep
- Protects against oxidative stress
What does Ashwagandha do?
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Ashwagandha (scientific name Withania somniferi) is also known as Indian ginseng, and by other names in Sanskrit, Hindi, and Tamil, including asgand, amukkirag, sand asvagandha.
The roots of this herb are believed to help energize and rejuvenate the nervous system.
It is said to help prevent or reduce stress related disorders caused by increases in cortisol (the ‘stress’ hormone) in the blood. It is also believed to boost the body’s immune system when stores of vitamin C have been depleted.
Clinical studies and laboratory studies have determined that Ashwagandha can modulate and stimulate a variety of immune system functions. Additionally, the herb is believed to have anti-inflammatory benefits as well as anti-aging effects.
The root, leaves, and berries of the Ashwagandha plant have long been utilized to support whole-body health and to reduce the inflammation caused by arthritis. The herbal remedy may also reduce fluid retention and swelling caused by inflammation.
Recent studies have also determined that Ashwagandha may relieve symptoms of osteoarthritis. Individuals with Type 2 diabetes may experience lowered blood sugar levels, as well as lower levels of bad or (LDL or low-density lipoprotein) cholesterol in the blood. Ashwagandha also has some sedative properties which may help reduce levels of stress and anxiety.
In the United States, Ashwagandha is available as a dietary supplement commonly used as a diuretic, a sedative, and an adaptogen, boosting the effects and function of the central nervous systems, the immune system, and inflammatory conditions.
Safe Dosages of Ashwagandha
When used properly and according to directions, Ashwagandha side effects are minimal.
Dosage recommendations for Ashwagandha differ depending on the age and overall health and wellness of the individual taking it. Dosage is also dependent on the form of Ashwagandha root taken.
This herb is available in tea form, leaves, tinctures, as well as supplement capsules or pills. Most use between 1 and 6 g of the whole herb to prepare tea. When using powdered supplements, 3 g may be adequate for brewing the tea.
In pill or capsule form, the extract from Ashwagandha root has been used in doses ranging from 450 mg to 2 g. It is most often combined with other herbs and preparations to alleviate anxiety and improve mood.
According to Drugs.com, side effects are mild and when used safely, Ashwagandha is non-toxic.
Ashwagandha Side Effects
Clinical studies that have examined the long term effects or side effects associated with use of Ashwagandha are lacking. When taken short-term and by mouth, Ashwagandha is relatively safe, although taking too much may cause side effects such as upset stomach, nausea, vomiting, or diarrhea.
Individuals diagnosed with certain conditions should use precautions and avoid Ashwagandha. These situations include pregnant or breast-feeding women, or if you have been diagnosed with stomach ulcers. In such situations, the herb is believed to irritate the stomach and intestinal tract.
Interactions of Ashwagandha with prescription medication are also possible. For example, individuals with diabetes should avoid use of this herb because it may lower levels of blood sugar (glucose) in the blood.
The herb may also decrease blood pressure due to sedative effects. Therefore, Ashwagandha in any form should not be taken if you are already taking medications to treat high or low blood pressure.
Avoid use of Ashwagandha if you have a thyroid disorder, as it may increase levels of hormones produced by the thyroid gland. This increase in hormones may interact negatively with prescription medications.
The same goes for diseases of the autoimmune system that include systemic lupus erythematosus, multiple sclerosis, or rheumatoid arthritis because it may increase activities of the immune system, which can in turn exacerbate symptoms of those conditions.
Finally, avoid taking Ashwagandha if you are taking any type of immunosuppressant medication. The same applies to sedatives including Valium, Klonopin, and Ativan. Ativan may also interact with over-the-counter as well as prescription sleep aids, including Ambien.
When taken correctly and in conjunction with your doctor or health practitioner’s knowledge and advice, Ashwagandha side effects are rare.
- Kataria H, Wadhwa R, Kaul SC, Kaur G. Water extract from the leaves of Withania somnifera protect RA differentiated C6 and IMR-32 cells against glutamate-induced excitotoxicity. PLoS One. 2012
- Rasool M, Varalakshmi P. Suppressive effect of Withania somnifera root powder on experimental gouty arthritis: An in vivo and in vitro study. Chem Biol Interact. 2006
- Chandrasekhar K, Kapoor J, Anishetty S. A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults. Indian J Psychol Med. 2012
- Gupta A, Mahdi AA, Shukla KK, Ahmad MK, Bansal N, Sankhwar P, Sankhwar SN. Efficacy of Withania somnifera on seminal plasma metabolites of infertile males: a proton NMR study at 800 MHz. J Ethnopharmacol. 2013
- Mikolai J, Erlandsen A, Murison A, Brown KA, Gregory WL, Raman-Caplan P, Zwickey HL. In vivo effects of Ashwagandha (Withania somnifera) extract on the activation of lymphocytes. J Altern Complement Med. 2009
- Khazal KF, Hill DL, Grubbs CJ. Effect of Withania somnifera root extract on spontaneous estrogen receptor-negative mammary cancer in MMTV/Neu mice. Anticancer Res. 2014
- Kataria H, Wadhwa R, Kaul SC, Kaur G. Withania somnifera water extract as a potential candidate for differentiation based therapy of human neuroblastomas. PLoS One. 2013
Article last updated on: May 12th, 2018 by Nootriment
5 Comments
I have been taken oral 600mg tablets (2 capsules per day for a total of 1200mg) for 7 months. Now with my routine blood work indicated my ferritin levels are at 413 normal is 12- 300. Could this be caused by taking Ganda? How much iron component is there in Ganda 6 mg?
Hi Janine,
According to ModernHerbalMedicine.com, “Ashwagandha contains a relatively high amount of iron (320mcg/g), giving a standard dose around 1 mg of iron.”
Lots of things can contribute to elevated iron levels. Check with your doctor to see if you should reduce your dosage of Ashwagandha and have the bloodwork repeated.
am 21 right now will i grow by using ashwagandha powder every day.
you can send me to my mail
Just started taking Ashwaghanda 500mg per day about a week ago because after extensive research, it stated that it normalizes T3 and T4 levels in both hypothyroidism and hyperthyroidism. I’ve been diagnosed hypo for 14 years and prescription drugs only make me worse. I currently only take multivitamin daily and ashwaghanda daily as well. The first 4 days I felt energized, and had hope that finally my thyroid is getting under control but it’s been 3 days I feel pain throughout body, trouble sleeping, and not a good overall feeling of well being. There is absolutely no interaction with any thyroid meds as I stopped taking those months ago. What could be the issue? Is 500mg too much for me? It seemed as if it was working fine and suddenly I’m not well. Please help.
I have hypothyroidism I am taking thyroxin will it help my thyroid also what can I take for hypothyroidism I want to stop taking thyroxin
Thanks