Bacillus coagulans benefits include treating IBS symptoms, such as pain, bloating and diarrhea. It is It is also helpful for preventing respiratory infections, for building up the immune system and reducing inflammation.
Bacillus coagulans is a spore-forming bacteria that exhibits a number of probiotic effects. It produces lactic acid in the intestines as well as an antibacterial substance called “coagulin”.
Taking a B. coagulans probiotic supplement can help to restore balance to the gut microflora following a disruption. This bacterium is able to survive the harsh, acidic conditions of the gastrointestinal tract and colonize the intestines when supplemented orally.
A thirty-day study published in Postgraduate Medicine in 2009 showed Bacillus coagulans helped improve the immune system to resist virus related respiratory tract infections of cold and flu.
Bacillus coagulans has also been shown to be beneficial in treating BV (Bacterial Vaginosis) and helped reduce residual inflammation of treated HV-1 infection patients.



- Supports a healthy immune system & microflora
- Promotes digestion & nutrient absoprtion
- Combats pathogenic bacteria; Improves metabolism
Bacillus Coagulans Health Benefits
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- Lactobacillus Acidophilus
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Bacillus coagulans (sometimes mistakenly referred to as Lactobacillus Sporogenes) is a Gram-positive rod, endospore forming, motile bacteria species.
This strain of probiotic bacteria does not naturally inhabit the human gut, but has been extensively used in veterinary medicine and is now being researched for its benefits on human health.
It works by normalizing the gastrointestinal microflora, helping to establish an environment that is inhospitable to disease-causing bacteria that can also cause inflammation, diarrhea, impaired digestive function and more.
This probiotic supplement may also strengthen the immune system response. Research shows that the presence of bacteria in the intestines can stimulate the production of antibodies, which identify and attack foreign antigens like bacteria and viruses.
In one research study, B. coagulans was also found to have a positive effect on rheumatoid arthritis symptoms. Administering the proprietary strain, Bacillus coagulans GBI-30, 6086 (also known as GanedenBC 30), resulted in improved functionality for patients when combined with standard anti-arthritic medications.
This probiotic supplement might work by reducing signs of inflammation and by exhibiting and immunomodulation effect for patients with rheumatoid arthritis. It was show to reduce levels for C-reactive protein (CRP) and improve the ability to walk for 2 miles.
A clinical study published in AIDS research and Human Retroviruses in October 2014 also showed this supplement may have benefits for patients with the HIV-1 infection.
The clinical data of the 3-month double-blind placebo-controlled trial demonstrated the safety and possible benefit of Bacillus coagulans GBI-30 for residual inflammation in treating HIV-1 infection.
Bacillus Coagulans Benefits for Digestion and IBS
Probiotics are often taken to improve digestive conditions, such as IBS and IBD. They have also been found effective for reducing symptoms of diarrhea by fighting the bacterial infections that can sometimes cause diarrhea.
Bacillus coagulans benefits include its use for treating IBS (Irritable Bowel Syndrome). An eight-week clinical study published in Postgraduate Medicine in 2009 showed this probiotic bacterium relieved symptoms related to IBS.
The patented strain used in this study was B coagulans GBI-30, 6086, and it was taken once per day for 8 weeks. No serious side effects were reported during the study period.
The clinical study concluded that those taking Bacillus coagulans showed a significant improvement in the bloating and pain symptoms compared to the placebo group.
Another eight-week clinical study published in Methods and Findings in Experimental and Clinical Pharmacology in 2009 showed Bacillus coagulans helped diarrhea predominant IBS patients significantly reduce the frequency of bowel movements compared the placebo group.
Bacillus Coagulans for BV
Bacillus coagulans has been used to improve the vaginal microflora in women. While probiotic bacteria are most often associated with the gastrointestinal tract, they also populate the urogenital tract and are important for preventing vaginal infections.
They help to combat the growth of pathogenic bacteria and yeast, such as Candida which is the most common cause of fungal infections in women. This probiotic has also been found effective for women diagnosed with BV (Bacterial Vaginosis).
A clinical study published in the Indian Journal of Microbiology in September 2012 showed the strain Bacillus coagulans Unique IS-2 was useful for women with a BV infection. This strain is patented by Unique Biotech Limited in India.
Forty women in the clinical study were diagnosed with BV. These women had symptoms of white discharge, a pH greater than 4.7, burning micturation (urination), itching, soreness and an inflamed vulva.
The probiotic group subjects were given the antibiotic therapy Ofloxacin-Ornidazole with strength of 200-500 mg per capsule a day for five days.
The clinical study women were also given vaginal peccaries (co-kimaxazol) for 3 days along with two probiotic capsules of Bacillus coagulans Unique IS-2. The control group only had the antibiotic therapy.
There was a significant improvement in the probiotic group with 80% of probiotic group subjects having a reduction of vaginosis symptoms compared to the control group percentage of 45%.
Bacillus Coagulans Safety
There are a number of different strains of Bacillus Coagulans probiotics on the market, and not all of them have been well-researched for their health benefits and potential side effects.
B coagulans GBI-30, 6086 is one strain that has been studied in a number of clinical trials with no safety concerns. This supplement was given FDA GRAS (Generally Regarded as Safe) status, which means it has a very low risk of side effects if used appropriately.
However, not all individuals are healthy enough to take probiotics. If you are using any immunosuppressant drugs or have an impaired immune system, check with your doctor before taking B. Coagulans.
This supplement is not recommended for women who are pregnant or nursing as there have not been any studies to evaluate safety for pregnant or breastfeeding women. Probiotics should also be avoided by those with open surgical wounds or using a catheter.
If taken probiotics with antibiotics, it is important to note that they will interact with each other. Your doctor will likely recommend that you use probiotics at least two hours apart from any antibiotic medications.
Bacillus Coagulans health benefits continue to be researched. Check with your doctor before using this supplement to address a specific health concern.
- Ratna Sudha Clinical Study of Bacillus coagulans Unique IS-2 (ATCC PTA-11748) in the Treatment of Patients with Bacterial Vaginosis. Indian J Microbiol 2012 Sep;52(3):396-9. doi: 10.1007/s12088-011-0233-z. Epub 2011 Sep 23.
- Zhao M, Structure and dynamics of the bacterial communities in fermentation of the traditional Chinese post-fermented pu-erh tea revealed by 16S rRNA gene clone library. World J Microbiol Biotechnol 2013 Oct;29(10):1877-84. doi: 10.1007/s11274-013-1351-z. Epub 2013 Apr 17.
- Alli SM, Development and evaluation of intestinal targeted mucoadhesive microspheres of Bacillus coagulans. Drug Dev Ind Pharm 011 Nov;37(11):1329-38. doi: 10.3109/03639045.2011.572889. Epub 2011 Jun 27.
- Miyamoto H, Potential probiotic thermophiles isolated from mice after compost ingestion. J Appl Microbiol 2013 Apr;114(4):1147-57. doi: 10.1111/jam.12131. Epub 2013 Feb 1.
- Yang OO, Immunomodulation of antiretroviral drug-suppressed chronic HIV-1 infection in an oral probiotic double-blind placebo-controlled trial. AIDS Res Hum Retroviruses 2014 Oct;30(10):988-95. doi: 10.1089/AID.2014.0181. Epub 2014 Sep 11.
- Drago L, Should Lactobacillus sporogenes and Bacillus coagulans have a future? J Chemother 2009 Aug;21(4):371-7.
Article last updated on: March 12th, 2018 by Nootriment