What are the best nootropic stacks that you can take to improve your cognitive capacity?
While some nootropics are effective on their own, you will derive far greater benefit by mixing a few different supplements together in a nootropic stack.
Stacking nootropics will allow you to get better results faster while also affecting several different dynamics of brain power at the same time.
Not sure what drugs you should be stacking together? This article will give you an idea of some of the most popular nootropic combinations that you might want to try and make for yourself.
You can also by some pre-formulated nootropic stack products like Alpha Brain or BrainStack if you do not want to do the work of mixing your own.



- Promotes brain health & communication
- Supports memory, reasoning & cognition
- oosts focus, mental clarity & attention
What is the Best Nootropic Stack?
Related Topics
- What are Nootropics?
- Nootropics List
- Types of Nootropics
- Effects & Benefits
- How Do Nootropics Work?
- Natural Nootropics
- Enhace Intelligence
- Boost Memory
- Improve Concentration
- Reduce Anxiety
- Treat Depression
- Nootropic Side Effects & Dangers
- How to Stack Nootropics
- Best Nootropic Stacks
- Strongest Nootropics
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We have a pretty simple formula for what we think makes the best nootropic stack: a racetam or Noopept + Choline source + (optional) natural nootropics.
Stick to this formula and you can be guaranteed that whatever stack you use will be good.
This formula also allows for quite a bit of customization and you can even add in other compounds like Adrafinil, Sunifiram, and Sulbutiamine or consider combining multiple racetams if you want.
You can make your stack as complex or as simple as you want it to be, but if you have these basic elements you will not go wrong.
Looking for more guidance? Below is our guide to building the best nootropic stack for your needs
First Component: Racetams or Noopept
Racetams are generally considered the most effective nootropics and are a vital part of any brain stack. It is up to you whether you chose Piracetam, Aniracetam, Oxiracetam or Pramiracetam for your stack; most beginners start with Piracetam and then upgrade to Aniracetam or Oxiracetam when they want something a little stronger.
If you have more experience with these supplements then Pramiracetam is a big step up in terms of cognitive power. Another option is to use Noopept which is a peptide and not a racetam, but it 1000x stronger than Piracetam according to academic studies.
How you pick which racetam is right for your nootropic stack is a matter of personal preference. Research each of these components to determine which offers benefits that meet your needs.
Some people will also stack several of these compounds together for increased synergy. For example, using Piracetam with Aniracetam is fairly common because of the distinct ways these nootropics work.
Other individuals will add additional smart drugs to their stack by using Adrafinil or Modafinil with a racetam. You might also want to consider other compounds like Sunifiram, Phenibut, or Pyritinol. Experimentation is the best way to find out what works for you.

- Focus longer, clear brain fog & feel more motivated
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- Contains 12 safe and natural nootropic ingredients
Second Component: A Choline Supplement
When you are using Piracetam, Noopept or any other racetam nootropic it is important to make sure you are getting sufficient amounts of Choline through your diet.
These compounds improve your memory, focus, cognition and learning capacity by increasing levels of the acetylcholine neurotransmitter. But in order for your body to make acetylcholine, you have to be consuming sufficient amounts of choline in your diet.
Unfortunately, only 10% of the population actually gets the right amount of choline bitartrate from what they eat. That is why using a Nootropic stack with choline is so important.
Choline significantly amplifies the effects of almost any other nootropic supplement you use, in addition to offering some brain boosting effects on its own.
There are five ways to use Choline when designing the best nootropic stack. You eat more high in choline foods such as egg yolks, though some people find the daily 8 egg requirement to be excessive.
The next option is to take Choline Bitartrate supplements which tend to be cheap and may even be included in some multivitamin products.
However Choline salts of this form are less effective when absorbed into the body and will got give you the full benefit. A better option is to use one of Alpha GPC, Centrophenoxine, or CDP Choline (Citicoline) – all three of which are excellent choline sources.
Try experimenting with these three compounds to decide which is best for your stack.
Third Component: Natural Nootropic Supplements
There are a wide range of natural and herbal nootropics that offer substantial cognitive benefits, but many people shy away from these supplements thinking that they are not very strong.
That is not the case: there are some highly potent natural nootropics that can dramatically improve your memory, concentration, and synaptic plasticity.
While you do not have to use these supplements to get good results, if you want to round out your stack a few herbal additions is a great idea.
Some of the top natural nootropics include Huperzine A, Vinpocetine, L-Theanine, Caffeine, Ginkgo Biloba, Bacopa, and Lion’s Mane. Because you will typically only take a small amount of each of these substances in combination, you may find it easier to purchase a pre-packaged natural nootropic stack like Alpha Brain or Brain Stack.
These products will give you a good mix of different cognitive enhancers that you can then add to your nootropic stack with the more powerful racetams and choline.
Give this combination a try the next time you are buying nootropics online and tell us about your results!
Article last updated on: February 3rd, 2018 by Nootriment
6 Comments
I want buy. Please tell me How buy you
There is no such thing the best nootropic. Every nootropic is different, and the best one is the one that will deliver the particular benefits you desire. For example, if you’re trying to eliminate stress and elevate your mood, you may want to try L-Tyrosine. Looking for a jolt to your brain’s performance? B6 might do the trick.
Remember, the best nootropics are safe, proven to be effective, and provide the type of cognitive enhancement benefits you desire.
My feelings exactly but with a slight addition to your last sentence…providing the cognitive enhancements you desire and that last!
With regards to the article…i think a choline source isnt necessary if nootropics whose mechanism is to decrease the reuptake of choline in the brain are taken as both do the same thing…increase choline availability in the brain. Or these kind of choline reuptake inhibitors shouldnt be taken if choline pills are taken. It will lead to a double whammy of choline. Its very important that this is kept in mind.
Another thing about choline, the earlier in the day it is taken the better, as it can keep up awake well into the night if taken later….for a lot of people.
Nevertheless it is a wonderful article.
I’m new to nootropics in terms of knowledge, but I’ve unknowingly consumed many in my past through experimentation of using various natural energy enhancers.
Just days ago I ordered the Alpha Brain, Shroom Tech Sport, amongst many other Onnit products – being that many people seem to love them. anyone had prior experience with Alpha Brain or other Onnit products? I’m excited to try it based off all the positive reviews I’ve observed.
I’ll have a product review soon on my blog – hedergy.com
Ok, I’ve tried a few, and not gotten any benefit from any of them.
Here’s what I’ve tried: Aniracetam, vinpocetine, phosphatidylserine, Alpha-GPC, DMAE, Vitamin B6+B12, and these days I’m trying Noopept+Alpha GPC, and I do not notice any benefit or improvement after using any of these. :(
I’ve been on the Noopept+Alpha GPC for two weeks now, taking about 30 mg’s of Noopept per day, and there’s just no noticeable difference.
I’m trying these for cognitive and memory improvement. Any suggestions for something else?
Hey buddHey buddy, I have found that high doses piracetam in conjunction with DMAE, l-tyrosine, and Alpha GPC open my brain up in ways I have never imagined. Mostly feel it when I have higher doses of piracetam, I was able to multi task at work like a pro just yesterday, it was amazing! I used to take it seven years ago, and have recently gotten back into the nootropics scene, I’m experimenting myselI’m experimenting myself, but I came back because I know that it works, you just gotta find what works for you!