Bifidobacterium infantis 35624 is a patented probiotic strain believed to provide benefits for the health of the human gastrointestinal tract.
B. infantis is one strain of Bifidobacteria, which is one of the most prominent families of bacteria that colonize the human digestive tract.
Bifidobacterium infantis is names for the fact that it is found in the highest ratio in the digestive tracts of newborn infants.
It makes up about 95% of the total gut bacteria (microbiome) of infants shortly after birth, but only constitutes 30% of the bacteria in the digestive tract of adults.
As a dietary supplement B. infantis 35624 is used to promote digestive health and to support the immune system. B infantis is a sub-species of the Bifidobacterium longum species and is able to remain viable through the GI tract to reach the gut.
In the intestines, Bifidobacterium infantis 35624 produces water soluble vitamins thiamine (Vitamin B1), nicotinic acid (B3) and folic acid (B9) as well as Vitamin B12 and pyridoxine (B6) and biotin (B7).
This probiotic also helps in the absorption of calcium, which can have benefits for bone healthy and people diagnosed with a calcium deficiency in their diet.



- Supports a healthy immune system & microflora
- Promotes digestion & nutrient absoprtion
- Combats pathogenic bacteria; Improves metabolism
Bifidobacterium Infantis 35624 Benefits
Related Topics
- What are Probiotics?
- Probiotic Benefits
- Best Probiotic Strains
- Probiotic Side Effects
- Probiotic Supplements
- Probiotic Foods
- Best Probiotic Yogurt
- Probiotics for Children
- Probiotics for Women
- Yeast Infections
- What are Prebotics?
- Lactobacillus Acidophilus
- Lactobacillus Bulgaricus
- Lactobacillus Rhamnosus
- Bifidobacterium Bifidum
- Bifidobacterium Infantis
- Bifidus Regularis
Supplementing the diet with B. infantis 35624 products may improve digestion, vitamin synthesis, nutrient absorption and reduce inflammation in the body. Probiotic bacteria in general are known to support the immune system by inhibiting the spread of pathogenic bacteria in the gastrointestinal tract.
This supplement can also be used to improve symptoms of a number of different digestive conditions. A clinical study published in Gut Microbes in July 2013 showed Bifidobacterium infantis 35624 reduces systemic immune system pro-inflammatory biomarkers in both gastrointestinal and non-gastrointestinal conditions.
Bifidobacterium infantis 35624 has anti-inflammatory properties and is used reduce visceral pain (pain in the organs) which is a common symptom of IBS. This probiotic also helps the other IBS symptoms of bloating, intestinal gas and bowel movement problems such as diarrhea, constipation and incomplete bowel movements.
Bifidobacterium infantis 35624 helps to restore the normal interleukin ratios in IBS. This helps to lessen the severe inflammation caused by this imbalance. Bifidobacterium infantis 35624 also helps to improve digestive function.
Bifidobacterium Infantis 35624 Effects
Bifidobacterium infantis thrives in the intestinal environment of breast-fed infants as it prefers the prebiotic human milk oligosaccharides (HMO’s) in human breast milk. This probiotic is also able to use glucose, fructose and other carbohydrates found in the whole-foods diet of older children and adults, just as other Bifidobacterium species of probiotic bacteria.
Bifidobacterium infantis produces mainly acetic acid, but it can also produce lactic and formic acid. The lactic and formic acid produced depends on the type of food available for consumption for the probiotic microorganisms.
Bifidobacterium infantis also produces a bacterocin-like inhibitory substance. Bacterocin are proteinaceous toxins produced by bacteria to inhibit the growth of similar or closely related bacterial strain.
This probiotic is able to prevent pathogenic Salmonella typhimurium and E. Coli from thriving and attaching to the cell walls of the intestines. This can further help to support the immune system and inhibit the colonization of pathogenic bacteria.
Bifidobacterium infantis 35624 is also used to prevent and to treat kidney stones by reducing urinary oxalate. Oxalate normally leaves the body through the urine. If the level is too high, it combines with calcium to form kidney stones.
B. Infantis 35624 for Depression
There is growing research interest into the effects of probiotic supplements on mood, cognitive function and brain health. This is believed to be regulated in part by the gut-brain axis.
This axis involves biochemical signaling between the gastrointestinal tract and the nervous system and involves the intestinal microbiota which is associated with healthy brain function as well as digestion. Gut microbiota may also regulate anxiety, cognition, mood and pain sensitivity.
Animal research shows that Bifidobacterium infantis can have a normalizing effect on mood. A clinical animal study of rats with depression that were treated with Bifidobacterium infantis started to exhibit normal behavior with a normal immune responses and normal levels of stress hormone.
Is Bifidobacterium Infantis 35624 Safe?
Probiotic supplements are generally considered safe with low risk of side effects for health adults. In some cases, using a probiotic tablet or yogurt enriched with these friendly microorganisms can cause mild side effects such as bloating, gas or diarrhea.
Bifidobacterium infantis 35624 is used by pregnant women and infants to enhance the immune system and is found in the newborn digestive system. This species of bacteria is naturally occurring in the human body; administration of appropriate doses of B. infantis 35624 in supplement form is unlikely to cause adverse effects.
However, there are some general contraindications against the use of probiotic products for certain groups of individuals who may be more susceptible to negative effects. Probiotics should not be taken by those with impaired immune systems, open surgical wounds or those using a catheter.
People with SBS (Short Bowel Syndrome) should also avoid probiotics due to the risk of bacterial migration. Probiotics can interact with any antibiotic medications and they should be taken a minimum of two hours apart from each other.
Where to Buy Bifidobacterium Infantis 35624
There are a number of different B. infantis probiotic products available on the market today. This supplement is usually sold in a complex form, combined with other species of Bifidobacterium and Lactobacillus probiotics.
Neocare is a powder that contains Bifidobacterium infantis 35624 and is used to help build up the probiotic ratio in newborns. It is administered either by placing it on the nipple or on the bottle teat. Neocare is for administration by health care professionals.
Good clinical result for treating IBS (Irritable Bowel Syndrome), pouchitis, traveler’s diarrhea and ulcerative colitis have been achieved with Bifidobacterium infantis 35624 and its use in combination probiotic formula VSL#3 (combination of 8 strains of live lactic acid bacteria (LAB).
- Groeger D, Bifidobacterium infantis 35624 modulates host inflammatory processes beyond the gut. Gut Microbes 2013 Jul-Aug;4(4):325-39. doi: 10.4161/gmic.25487. Epub 2013 Jun 21.
- Konieczna P, Immunomodulation by Bifidobacterium infantis 35624 in the murine lamina propria requires retinoic acid-dependent and independent mechanisms. PLos One 2013 May 21;8(5):e62617. doi: 10.1371/journal.pone.0062617. Print 2013.
- Scully P, Bifidobacterium infantis suppression of Peyer's patch MIP-1? and MIP-1? secretion during Salmonella infection correlates with increased local CD4+CD25+ T cell numbers. Cell Immunol 2013 Feb;281(2):134-40. doi: 10.1016/j.cellimm.2013.03.008. Epub 2013 Apr 11.
- Johnson AC, Effects of Bifidobacterium infantis 35624 on post-inflammatory visceral hypersensitivity in the rat. Dig Dis Sci 2011 Nov;56(11):3179-86. doi: 10.1007/s10620-011-1730-y. Epub 2011 May 12.
- Whorwell PJ, Efficacy of an encapsulated probiotic Bifidobacterium infantis 35624 in women with irritable bowel syndrome. Am J Gastroenterol 2006 Jul;101(7):1581-90.
- Brenner DM, Bifidobacterium infantis 35624: a novel probiotic for the treatment of irritable bowel syndrome. Rev Gastroenterol Disord 2009 Winter;9(1):7-15.
Article last updated on: April 6th, 2018 by Nootriment