Arcalion is a brand-name nutritional supplement with extensive benefits for brain metabolism, memory and mood.
It contains the active ingredient Sulbutiamine which is a synthetic fat-soluble version of Vitamin B1 (Thiamine) that can more readily cross the blood-brain barrier.
This can result in cognitive function improvements including the abilities to focus, reason, retain information, and work productively for long spans of time. Arcalion is also observed to counteract fatigue without overly-stimulating the user in comparison to stimulant products like amphetamines or caffeine.
You can buy Arcalion in a number of different places and formats, but how you buy it will make a lot of difference in terms of the price you pay per dosage. Some sources of Arcalion for sale are much cheaper than others just based on which name it is sold under.



- Heightened alertness, focus & energy
- Supports memory & mental performance
- Promotes mood through dopaminergic activity
Arcalion Drug Information
Related Topics
- What is Sulbutiamine?
- What is Arcalion?
- User Reviews
- Effects and Benefits
- Why Take Sulbutiamine?
- Sulbutiamine for Energy
- Effects on Dopamine
- Dosage Guidelines
- Sulbutiamine for Anxiety
- Possible Side Effects
- Bulk Sulbutiamine Suppliers
- Buying Sulbutiamine Online
- Arcalion Uses
- How to Take Arcalion
- Is Arcalion Safe?
- Buy Arcalion
Arcalion, or Sulbutiamine (isobutyryl thiamine disulfide), is used in some countries as a drug used to treat asthenia and other forms of fatigue and weakness with neurological causes.
From a structural point of view, it is essentially two modified Thiamine molecules which have been chemically bonded together by sulfur.
This makes Sulbutiamine lipophilic so that it can more readily enter into the brain when it is ingested. It is more bioavailable then traditional Thiamine, and the altered structure also gives slightly different mechanisms of action in the brain.
At this time, the FDA has not approved Sulbutiamine as a drug to prevent or treat any conditions. Arcalion tablets or powder are legally sold in the USA as dietary supplements however, and are frequently used by individuals as powerful concentration aids.
Arcalion reviews say that this supplement helps them to focus for many hours at a time and gives them more mental energy without causing restlessness or an energy-crash. One of the ways in which Arcalion works is by modulating the levels of various neurotransmitters produced within the brain.
An example is Acetylcholine, an important brain chemical which plays a vital role in cognitive and mental processes like memory formation. Acetylcholine is also involved in executive function and attentional control which can enable you to experience intense concentration without becoming distracted.
Arcalion also affects levels of circulating Dopamine in the brain. Not only is Dopamine known to improve mood and motivation, it also has a role to play in attentional control and the ability to focus all of your mental energy on the task at hand.
As a derivative of Thiamine, Arcalion is also known to support energy production in your cells. This vitamin is essential for turning the sugar consumed by the body into energy.
One of the primary effects of Thiamine in the body is to take part in the synthesis of ATP, an energy storage molecule used by your cells. Thiamine deficiency can cause a number of neurological problems such as chronic fatigue, beriberi, and Alzheimer’s.
By using Arcalion pills, even healthy adults can cause an increase in ATP generation in the brain. This supplement also helps to support a healthy nervous system. It encourages the development and growth of myelin sheaths, which cover most of the nerves in the body.
Myelin sheaths are used for protection, but they also help to make neuron communication more efficient. If they become damaged it can lead to pain and other uncomfortable effects as well as impairments in cognitive processing.
Arcalion offers a number of Nootropic benefits such as improving one’s memory and learning capacity. This is likely due to the fact that taking Arcalion can increase the efficiency and responsiveness of synapses in your brain.
Users who take Arcalion supplements say that they experience a faster speed of memory recall and even overall cognition.
It may facilitate more communication between different areas of the brain, causing users to say they feel their thoughts are more fluid. This is interpreted to mean that it requires less conscious mental effort to perform tasks like writing, reading, and problem solving.
Other users have reported improved sensory perceptions, especially those related to sight and sound. In general, taking Arcalion may make your brain more responsive and raise your level of fluid intelligence.
How to Buy Arcalion
If you are planning to buy Arcalion to use on a regular basis, it is important to find the best quality product for the cheapest price. There are many different Arcalion vendors that have popped up recently, a number of which are based overseas and are affiliated with offshore pharmacies.
However, you do not have to buy Arcalion from a pharmacy. In the United States, it is legal to purchase it as a supplement, though here it goes by the generic name Sulbutiamine instead.
Sulbutiamine is almost always more popular than buying Arcalion due to the fact that Arcalion is a more expensive brand name product. You can save yourself significant amounts of money by purchasing the generic Sulbutiamine compound, especially when planning to use it in a nootropic stack.
If you have decided to buy Sulbutiamine instead of Arcalion, the next question is usually which formulation to buy. You will find it sold in capsules, pills, and tablets which can be convenient for taking with you and using during the day. However, these products tend to be much more expensive than if you were to buy your supplements in powder form.
Sulbutiamine powder can be three times less expensive in comparison to the pills. For example, you can buy 50 g of bulk Sulbutiamine for $29.99 which will cost approximately $0.30 per day for a typical dosage.
Another reason to use it in bulk powder format is that it avoids the fairly long process of breaking down the physical pill which can slow down the responsiveness of the supplement. A powdered formulation, in contrast, works a bit differently.
Once ingested, the supplement goes into the bloodstream almost immediately. There is nothing to break down since the main ingredients are already there in free form. With a powder you are also able to control your own dosage much more accurately. You can measure out the dosages with a set of micro measuring spoons or you can decide to get an electric weight scale.
Using Arcalion
Once you have purchased your source of Arcalion or generic Sulbutiamine, determine your proper dosage is important. Proper dosage depends on many different factors, and it is recommended that you speak with your doctor to determine the best dosage for your needs. The below dosage recommendations are general guidelines only, and your dosage may be different.
The recommended dosage range is between 200 and 1,000 mg per day. Most people will use 400 mg per day, especially when stacking Arcalion with other compounds like Aniracetam, Piracetam, Choline or Noopept.
Always start out with the lowest effective dose to observe how it affects you for about a week before increasing your dose. New users are cautioned to not go above about 600 mg per day.
The best way to take this supplement is preferably along with meals. Since it is fat-soluble this helps with absorption and bioavailability factors. Most people take Arcalion powder three times a day, with each meal. However, it could just as easily be used only once or twice. This is a personal decision based upon your reason for taking it in the first place.
Because Arcalion has an energy-boosting effect, you should not be using it too late in the day or it can prevent you from falling asleep as your normal time.
Arcalion is a safe supplement with a high tolerability profile. There may be few side effects, but most are only seen in those taking higher than average doses. Arcalion side effects may include skin rashes similar to those from eczema, possible mood swings, and difficulty sleeping.
It should not be given to a child unless under doctor advice. When taken in high doses, there is also the risk of dependence.
This is likely stemming from the fact that too much Arcalion may shut down the body’s natural production of Dopamine, which can result in a ‘crash,’ similar to being depressed or burned out after drinking a lot of energy drinks. The best way to avoid this problem is to stay within the recommended limits for usage and to cycle the supplement with some frequency.
You can use and buy Arcalion safely, but it is important to follow these precautions to get the most out of the nootropic.
- Kiew KK, Wan Mohamad WB, Ridzuan A, Mafauzy M. Effects of sulbutiamine on diabetic polyneuropathy: an open randomised controlled study in type 2 diabetics. Malays J Med Sci. 2002
- Kwag J, Majid AS, Kang KD. Evidence for neuroprotective effect of sulbutiamine against oxygen-glucose deprivation in rat hippocampal CA1 pyramidal neurons. Biol Pharm Bull. 2011
- Trovero F, Gobbi M, Weil-Fuggaza J, Besson MJ, Brochet D, Pirot S. Evidence for a modulatory effect of sulbutiamine on glutamatergic and dopaminergic cortical transmissions in the rat brain. Neurosci Lett. 2000
- Ahmed MA, Elbeshlawy MM. Potentiometric sensors for the selective determination of sulbutiamine. J Pharm Biomed Anal. 1999
- Kang KD, Majid AS, Kim KA, Kang K, Ahn HR, Nho CW, Jung SH. Sulbutiamine counteracts trophic factor deprivation induced apoptotic cell death in transformed retinal ganglion cells. Neurochem Res. 2010
- Van Reeth O. Pharmacologic and therapeutic features of sulbutiamine. Drugs Today (Barc). 1999
Article last updated on: March 13th, 2018 by Nootriment