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Capsicum cream is used to alleviate pain from arthritis, injuries, chronic back pain, neuropathic disorders (related to nerve dysfunction), gout, shingles and some skin disorders that cause itching.
Capsaicin is a natural phytochemical found in chili peppers from the botanical genus Capsicum. It causes these peppers to have a spicy taste by activating TRPV1 receptors in the body, which are associated with the perception of heat and pain.
Capsaicin is FDA-approved for the treatment of pain of the neuropathic and musculoskeletal origin. Multiple clinical studies have shown that topical application of capsaicin-containing creams can provide temporary relief of chronic pain.
These creams contain between 0.25% and 0.75% capsaicin. They are available in pharmaceutical grade by prescription, and there are some OTC (over the counter) capsicum creams as well. Some other products with capsaicin include muscle rubs and “heat” patches.
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Top Capsaicin Products* ❯Capsicum Cream Uses
The Natural Medicines Comprehensive Database NMCD) states that capsicum creams are used to relieve pain associated with:
- HIV-associated neuropathy;
- Postherpetic neuralgia;
- Trigeminal neuralgia;
- Rheumatoid arthritis;
- Diabetic neuropathy;
- Prurigo nodularis;
- Muscle spasms;
- Osteoarthritis;
- Fibromyalgia
- Psoriasis;
- Shingles;
Capsicum creams with capsaicin extract are also used to help relieve arthritis, muscle strains, back aches, bruising and other conditions that may be determined by a medical professional. [1]
This cream is also used for cyclic vomiting, hair growth, weight loss, hair growth and more.
Capsicum Cream Brands
According to Drugs.com, there are various brands of capsicum creams, including Axsain, Capsicum Oleoresin, Capsin, Capzasin, Castiva Warming and GNP Capsaicin.
Some others include Icy Hot PM Patch, Menthac Arthritis Cream with Capsaicin, Qutenza, Salonpas Pain Patch with Capsaicin, Sloan’s Liniment, Trixaicin, Zostrix. [2]
How do capsicum creams work to relieve pain?
Researchers do not yet understand the precise mechanisms that make capsaicin effective for relieving chronic pain.
It is believed that capsaicin alters the levels of Substance P; a neurotransmitter and neuromodulator that sends pain messages to the brain.
Capsaicin is a selective TRPV1 receptor agonist, which means that it stimulates or turns on this polymodal nociceptor. By stimulating this receptor, it may cause it to develop a tolerance and subsequently down-regulate to become less sensitive to pain triggers.
More specifically, topical application of capsicum cream is thought to relieve pain by:
- Binding to the skin’s nociceptors and thermoreceptors;
- Exciting local neurons; heightening their sensitivity;
- Causing blood vessels in the skin to dilate (cutaneous vasodilation);
Subsequently, there is a refractory period when the neurons become less sensitive. According NMCD, “After repeated applications, persistent desensitization occurs, possibly the result of substance P depletion.” [2] [3]
Capsicum Cream Safety Warnings
Never use a capsicum product that contains ingredients you are allergic to. Read the ingredients carefully in any products you may choose.
You should seek medical advice before using capsaicin-containing products if you:
- Are pregnant, lactating or trying to become pregnant;
- Have known allergies to medicines and/or foods;
- Are taking any prescription medications;
- Regularly use herbal supplements;
Do not apply capsicum creams to open wounds – or skin that is irritated, burnt or otherwise damaged.
These creams have been used in children, but it is recommended to consult with a doctor first before applying the cream.
Using Capsicum Cream
If your doctor prescribed a capsicum cream for topical neuropathic analgesia or any condition you may have, then discuss application instructions with him or her before beginning use.
Read all dosing instructions that are on the label of the cream you are using. Compare that information with what your doctor told you. If there are any discrepancies, discuss them with your doctor.
Use capsicum creams sparingly, according to directions, Apply a small amount on the area to be treated. Massage it into the skin until it is well absorbed.
Unless it is your hands being treated, wash your hands thoroughly after applying a capsicum cream.
Be careful to not get capsaicin-containing products in mucosal tissues – like the eyes, nose, mouth and lips. This can cause irritation, stinging and burning. If you do get capsicum cream on these areas, then flush liberally with water.
After applying a capsicum cream, leave the treated area in open air. It is not recommended to cover the area with a bandage or heating pad. Also, protect the treated area from exposure to direct heat or sunlight, as this may intensify itching and burning.
You should not apply capsicum creams directly after sunbathing, bathing, swimming, use of a hot tub or other activities that expose you to heat. Cool down completely before apply the cream.
Capsicum Cream Side Effects
According to Drugs.com, the following side effects are possible with capsaicin-containing products including topical capsicum creams, topical films, topical gels, topical liquids, topical lotions and topical sticks.
The most common reported side effect of using capsaicin products is a condition called erythema. This is marked by temporary and superficial redness on the skin at the application site. This occurs in roughly 63% of users.
About 42% of users report pain at application sites, but this almost always subsides quickly, most likely due to the depletion of Substance P. [3]
Other common side effects associated with capsicum cream usage include application site pruritus (severe itching), edema, swelling and/or dryness.
Less common side effects of capsicum creams include hypertension (high blood pressure), AV (atrioventricular) block, heart palpitations and/or tachycardia (rapid heart rate).
Other possible side effects include dermatological conditions like abnormal skin odor and second degree burns.
Respiratory side effects may include bronchitis, sinusitis and/or swollen nasal passages (nasopharyngitis). Throat irritation and coughing are also possible.
Other possible side effects of capsicum creams include sneezing, lacrimation (tearing), rhinorrhea (runny nose), dyspnea (labored breathing), wheezing and exacerbation of asthma.
Nausea, vomiting, headache, dizziness and faintness have also been reported by capsicum cream users.
Article last updated on: July 23rd, 2018 by Nootriment