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Buy Now on Amazon *CarnoSyn is a proprietary beta alanine supplement manufactured by Natural Alternatives International (NAI). It is formulated for increased bioavailability to increase levels of the dipeptide carnosine in muscle tissues.
According to the manufacturers of CarnoSyn, this supplement has been shown to result “in greater physical working capacity, enhanced endurance and delayed fatigue.”
The active ingredient in CarnoSyn is Beta alanine (BA), an amino acid which is mainly used inside the body to manufacture carnosine. Elevating intramuscular carnosine levels is associated with enhanced proton buffering.
This subsequently leads to decreased muscle fatigue, and improvements in certain other markers of physical performance. Beta alanine supplementation is popular amongst athletes including bodybuilders, cyclists, runners, sprinters, rowers and HIIT (high intensity interval training) enthusiasts.
In addition to the standard form of CarnoSyn, there is also a Sustained Release version that gets absorbed by the body at a slower rate. This product reduces one of the adverse effects of taking beta-alanine, which is a tingling sensation in the extremities.
CarnoSyn can be found as the active ingredient in a number of different bodybuilding and energy supplements. It can also be purchased in a single-ingredient formulation from Amazon and other health product retailers online.
Body- building
Pre- Workout
Stamina- Supports muscle growth & workout performance
- Improves athletic stamina & power output
- Increases muscle carnosine levels
Effects of CarnoSyn
Related Topics
CarnoSyn beta alanine has also been shown effective for helping elderly persons to function better physically. By decreasing time to muscular fatigue and exhaustion, BA may help to reduce falls and otherwise add to the quality of life.
Routine supplementation may help to prolong the ability to live independently in elderly individuals.
According to its manufacturer (Natural Alternatives International (NAI), CarnoSyn beta alanine is clinically proven to:
- Elevate muscle carnosine levels over prolonged time periods;
- Increase the buffering capacities of muscles;
- Facilitate recovery from workouts;
- Decrease muscular acidosis;
- Increase muscular strength;
- Delay muscular fatigue;
- Increase endurance;
NAI also produces a Sustained Release (SR) CarnoSyn supplement that provides a higher dosage with a lower risk of side effects. This formulation can also extend the period of increased carnosine synthesis in the body, reducing in greater muscle retention of this compound.
CarnoSyn Beta Alanine for Athletes
Research on CarnoSyn beta alanine shows that it can increase muscle carnosine concentrations rapidly and significantly. In one 10-week study, intramuscular carnosine levels increased by more than 80% with daily usage.
In a 4-week study, CarnoSyn beta alanine apparently caused a 16.9% increase in work capacity in male subjects. Female subjects experienced a 12% increase in the same metric. In an 8-week study, trained endurance cyclists experienced an 11.4% increase in peak power output.
In a 7-week study, highly trained professional rowers improved rowing times. In 2000-meter rows, times were decreased on average by 4.3 seconds. In a 6-week trial, HIIT participants significantly delayed fatigue thresholds.
CarnoSyn Beta Alanine for the Elderly
A 2012 study investigated the effects of CarnoSyn beta alanine administration on muscle carnosine content and physical performance capacities. All eighteen subjects were between 60 and 80 years of age. All subjects were healthy and randomly assigned into either a treatment or placebo group.
12 subjects received two 800 mg CarnoSyn beta alanine sustained-released tablets twice daily for 12 weeks. That is a total of 3.2 grams daily. The remaining 6 subjects received a placebo agent instead.
Baseline and 12-week assessments were made concerning the following:
- Anaerobic exercise capacities;
- Muscle carnosine content;
- Physical activity levels;
- Food intake levels;
- Muscle function;
- Quality of life;
The group receiving CarnoSyn beta alanine showed an 85.4% increase in intramuscular carnosine relative to the placebo group (+7.2%).
Constant-load submaximal time-to-exhaustion test scores significantly improved in treatment group members (+36,5%), but not in the placebo group (+8.6%).
Time-to-exhaustion measurements in incremental tests also improved strongly in the treatment group (12.2%) compared to the placebo group (+0.1%).
Results from this study showed that CarnoSyn beta alanine increases muscle carnosine concentrations in elderly individuals. These increases are associated with enhanced physical performance capacities.
Using CarnoSyn Supplements
CarnoSyn beta alanine supplements are available in powders, capsules, tablets, lozenges, liquids and other forms. Powder forms are most demanded and are odorless, free-flowing and slightly hygroscopic (absorbs moisture).
The taste of CarnoSyn is neutral and said to blend well in various liquids. It is stable in powder form in temperatures up to 210 degrees Celsius. CarnoSyn has a 2-year shelf life when stored in original containers.
CarnoSyn supplements are typically used in a daily dosage of 3.2 – 6.4 grams. This dosage may be split into 1 – 4 doses per day with a maximum of 1.6 grams per dose to prevent side effects.
The supplement should be taken for a “Loading Period” of at least four weeks to notice significant increases in muscle carnosine levels.
CarnoSyn Beta Alanine Side Effects
Multiple studies show the general safety and tolerability of CarnoSyn brand beta alanine. There are no major side effects associated with its routine usage.
Temporary paresthesia (skin tingling) is experienced in some users. This effect goes away naturally within an hour or so. The temporary type of paresthesia caused by beta alanine is harmless. Reduce the dosage or use the SR CarnoSyn supplement to avoid this adverse reaction.
Minor possibilities also exist for irritation to the digestive tract, respiratory tract, skin and/or eyes. These effects are very uncommon.
CarnoSyn beta alanine is rated as possibly safe for appropriate oral usage in the short term. Young adults have used CarnoSyn without side effects for 10 consecutive weeks at daily doses up to 6.4 grams. In adults 55 years of age and older, CarnoSyn has been used safely in 2.4-gram daily doses for 3 months.
To ensure optimal effect of CarnoSyn beta alanine, it is best to engage a loading phase of supplementation. NAI recommends loading with 3.2 grams daily for a period of at least 4 weeks.
NAI recommends dividing daily dosages into 1.6-gram doses to be taken several times daily. This helps to avoid paresthesia symptoms and optimize BA availability. Notably, research shows that some users of CarnoSyn enjoy the paresthesia as it makes them feel that the substance is working actively inside their bodies.
There is not enough information about CarnoSyn beta alanine effects on lactation and pregnancy to establish its safety. Usage is not recommended without medical advice and monitoring in pregnant or nursing women.
- del Favero S1, Roschel H, Solis MY, Hayashi AP, Artioli GG, Otaduy MC, Benatti FB, Harris RC, Wise JA, Leite CC,Pereira RM, de Sá-Pinto AL, Lancha-Junior AH, Gualano B. Beta-alanine (Carnosyn™) supplementation in elderly subjects (60-80 years): effects on muscle carnosine content and physical capacity. Amino Acids. 2012 Jul;43(1):49-56. doi: 10.1007/s00726-011-1190-x. Epub 2011 Dec 6.
- Marina Yazigi Solis,#1 Simon Cooper,#2 Ruth M Hobson,2 Guilherme G. Artioli,1 Maria C. Otaduy,3 Hamilton Roschel,1 Jacques Robertson,2 Daniel Martin,2 Vitor S. Painelli,1Roger C. Harris,4 Bruno Gualano,1,* and Craig Sale#2,* Effects of Beta-Alanine Supplementation on Brain Homocarnosine/Carnosine Signal and Cognitive Function: An Exploratory Study PLoS One. 2015; 10(4): e0123857. Published online 2015 Apr 14. doi: 10.1371/journal.pone.0123857
- Trexler ET1, Smith-Ryan AE1, Stout JR2, Hoffman JR2, Wilborn CD3, Sale C4, Kreider RB5, Jäger R6, Earnest CP7,Bannock L8, Campbell B9, Kalman D10, Ziegenfuss TN11, Antonio J12. International society of sports nutrition position stand: Beta-Alanine. J Int Soc Sports Nutr. 2015 Jul 15;12:30. doi: 10.1186/s12970-015-0090-y. eCollection 2015.
- Julie Y. Culbertson,1,* Richard B. Kreider,1 Mike Greenwood,2 and Matthew Cooke3 Effects of Beta-Alanine on Muscle Carnosine and Exercise Performance:A Review of the Current Literature Nutrients. 2010 Jan; 2(1): 75–98. Published online 2010 Jan 25. doi: 10.3390/nu2010075
- Lancha Junior AH1, de Salles Painelli V2, Saunders B2, Artioli GG2. Nutritional Strategies to Modulate Intracellular and Extracellular Buffering Capacity During High-Intensity Exercise. Sports Med. 2015 Nov;45 Suppl 1:71-81. doi: 10.1007/s40279-015-0397-5.
- Stegen S1, Stegen B1, Aldini G2, Altomare A2, Cannizzaro L2, Orioli M2, Gerlo S3, Deldicque L4, Ramaekers M4, Hespel P4, Derave W1. Plasma carnosine, but not muscle carnosine, attenuates high-fat diet-induced metabolic stress. Appl Physiol Nutr Metab. 2015 Sep;40(9):868-76. doi: 10.1139/apnm-2015-0042.
- Liu T1, Peng YF, Jia C, Yang BH, Tao X, Li J, Fang X. Ginsenoside Rg3 improves erectile function in streptozotocin-induced diabetic rats. J Sex Med. 2015 Mar;12(3):611-20. doi: 10.1111/jsm.12779. Epub 2014 Dec 1.
- Jordan T1, Lukaszuk J, Misic M, Umoren J. Effect of beta-alanine supplementation on the onset of blood lactate accumulation (OBLA) during treadmill running: Pre/post 2 treatment experimental design. J Int Soc Sports Nutr. 2010 May 19;7:20. doi: 10.1186/1550-2783-7-20.
- Gottesmann C1. GABA mechanisms and sleep. Neuroscience. 2002;111(2):231-9.
- Kern BD1, Robinson TL. Effects of ?-alanine supplementation on performance and body composition in collegiate wrestlers and football players. J Strength Cond Res. 2011 Jul;25(7):1804-15. doi: 10.1519/JSC.0b013e3181e741cf.
- Ulrich P1, Cerami A. Protein glycation, diabetes, and aging. Recent Prog Horm Res. 2001;56:1-21.
- Close GL1, Hamilton L2, Philp A3, Burke L4, Morton JP5. Close GL1, Hamilton L2, Philp A3, Burke L4, Morton JP 5. Free Radic Biol Med. 2016 Feb 4. pii: S0891-5849(16)00030-7. doi: 10.1016/j.freeradbiomed.2016.01.016. [Epub ahead of print]
- Suzuki Y1, Ito O, Mukai N, Takahashi H, Takamatsu K. High level of skeletal muscle carnosine contributes to the latter half of exercise performance during 30-s maximal cycle ergometer sprinting. Jpn J Physiol. 2002 Apr;52(2):199-205.
- Solis MY1, Cooper S2, Hobson RM2, Artioli GG1, Otaduy MC3, Roschel H1, Robertson J2, Martin D2, S Painelli V1, Harris RC4, Gualano B1, Sale C2. Effects of beta-alanine supplementation on brain homocarnosine/carnosine signal and cognitive function: an exploratory study. PLoS One. 2015 Apr 14;10(4):e0123857. doi: 10.1371/journal.pone.0123857. eCollection 2015.
Article last updated on: April 5th, 2018 by Nootriment