Celastrus Paniculatus is a deciduous vine plant which grows natively throughout the Indian subcontinent. It has been used in various Indian cultural and medical traditions, such as Ayurveda and Indian Unani.
The plant, which is widely known as the “intellect tree,” is used to both sharpen mental focus and relax the nerves. It is considered by some to be a more effective memory supplement than the ginkgo biloba herb.
These effects are at least partly achieved through the inhibition of reuptake of various important neurotransmitters relating to cognitive performance. Celastrus Paniculatus is also connected to vivid and lucid dream states.
The following is a summary of how the Celastrus plant works, as well as the best ways to take it for optimum cognitive benefits.

- Focus longer, clear brain fog & feel more motivated
- Boost energy, alertnes & memory
- Contains 12 safe and natural nootropic ingredients
Celastrus Paniculatus Effects
Related Topics
- Best Brain Supplements
- What are Nootropics?
- Nootropics List
- How Do Nootropics Work?
- Natural Brain Boosters
- Brain Vitamins
- Increase your IQ
- How to Improve Concentration
- How to Improve Memory
- Focus Supplements
- Best ADHD Supplements
- Mood Enhancers
- Supplements for Anxiety
- Nootropics for Depression
- Best Brain Foods
- Does Brain Training Work?
- Brain Hacking
- Smart Drugs
- Cognitive Enhancement
The majority of the effects caused by Celastrus Paniculatus appear to be related to the neurochemicals dopamine, serotonin, and norepinephrine.
The plant delays the reuptake of these natural substances, meaning amounts of the chemicals stay high in the brain.
Dopamine is the neurotransmitter which generates feelings of intense mental focus, drive, and passion. It is most closely tied with the perception of mental energy, as well as physical pleasure.
5-HTP is the chemical per-cursor to serotonin, the chemical which generates feelings of contentedness and peaceful satisfaction.
Norepinephrine (noradrenaline) is a part of the body’s “fight or flight” mechanism, which elevates metabolism in nerve cells in order to make quick decision-making possible in times of stress.
Celastrus Paniculatus has also been observed to boost the amount of acetylcholinesterase enzyme in rat test subjects. This enzyme is closely tied to memory functions in the brain.
Celastrus Paniculatus Benefits
Celastrus Paniculatus has been described by users online as a “brain tonic.” It produces a light, refreshing burst of mental energy within a short while of consumption. It creates the feeling of fluid, alert thoughts, and heightened concentration. It can be taken as a potent and effective stimulant which makes schoolwork or other detail oriented tasks easier to focus upon and complete.
Some describe the effects as more intense and dramatic boosts to cognitive functions, on par with strong nootropic supplements like oxiracetam. Oxiracetam is considered one of the strongest and most efficient of all “smart drugs,” famous for producing intense concentration and memory effects.
One unique benefit of C. Paniculatus is its effect upon dreams. Almost all users report an immediate increase in the vividness of dreams, as well as the sporadic ability to exert conscious control over dreams, a technique known as lucid dreaming. The plant is sometimes marketed expressly for this purpose.
In general, it is suggested for use as a memory enhancing simulant with strong mood-lifting qualities. It is even used as an effective aphrodisiac. Some head shops sell the seeds as male libido enhancers.
Celastrus Paniculatus Dosage
The onset of the effects of Celastrus Paniculatus is rapid following ingestion, and does not take weeks of dosing to achieve optimum effects.
The same has often been said of the serotonin boosting supplement 5-htp when it is taken on its own. A strong single dose will create effects within an hour or two at most.
The majority of Celastrus sold online comes in the form of individual seeds. The traditional method for consuming the plant is to chew upon and/or swallow the seeds. A dosage between 7 – 20 seeds can produce noticeable benefits for most people.
C. Paniculatus is also sold as an extracted oil. The oil is generally sold in 100 mg increments. A starting dose could be as low as 5 – 10 mg daily.
As the supplement is considered strong by most users, it is best to start with a much lower dosage than the maximums recommended. After noting effects, dosage can be raised on subsequent days.
Celastrus Paniculatus Side Effects
The Celastrus Paniculatus plant extract is non-toxic. Tests with rats found the plant to be stable and non-toxic even up to doses of 5 grams, which is dozens of times higher than an effective human dose. Prolonged use in the same tests indicated that the plant may cause impairment to the liver, intestines, and testes over time.
It is unclear if moderate human use will have these effects, but anecdotal evidence from centuries of use in Ayurveda do not indicate any additional side effects.
Celastrus Paniculatus Review
Celastrus Paniculatus is an organic plant that has been used safely in Ayurveda and other Indian medicinal traditions for many centuries. It boosts amounts of serotonin, dopamine, and noradrenaline in order to create increased mental focus. It also improves memory with the support of the acetylcholinesterase enzyme.
The plant, which is consumed in seed form, can be very strong for some people, and is on par with established nootropic cognitive enhancers such as oxiracetam. Oxiracetam and 5-htp supplements will produce very similar effects and can be substituted for Celastrus Paniculatus, which is somewhat rare online.
Article last updated on: April 28th, 2018 by Nootriment
5 Comments
Existem relatos de experiências negativas com a celastrus? Consumi cerca de 8 sementes à noite e, no dia seguinte, passei muito mal, com sintomas de pressão alta (dor de cabeça, tontura) e febre interna. O único medicamento que tomo diariamente é a Venlafaxina 215mg, um antidepressivo. Fora isso, não fiz nem consumi nada que saísse do meu habitual, apenas as sementes.
Francine, alguns antidepressivos atuam justamente na recaptação do neurotransmissor serotonina, se estiver correto (não achei fonte confiável) o que está aqui escrito sobre as sementes Celastrus atuarem também na recaptação de neurotransmissores, podem ter havido SIM alguma interação. No seu caso, evitaria o uso enquanto não acho estudos científicos atestando sua forma de ação, tomaria mais cuidado futuro (avisando o profissional que auxilia e estudando) e caso me bem certificasse antes veria como uma possível saída mais saudável. Bjs de luz
I thought the idea was to inhibit acetylcholinesterase release in the brain. What good is it if it instead boosts this neurotransmitter in the brain. I think you should get your facts straight if you want to impress your readers.
Hi Memma,
Acetylcholinesterase is an enzyme and not a neurotransmitter. There are certain models in which diminished acetylcholinesterase activity is a marker for memory impairment. In one study, Celastrus Paniculatus was administered to rats induced to have Alzheimer’s. CP prevented the onset of aluminum induced neural insult, which was in part measured by preventing a predicted decrease in acetylcholinesterase concentrations.
Here’s a link to the relevant study: https://www.ncbi.nlm.nih.gov/pubmed/22629092
*drops the mic*