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Cerebrolysin is a neurotrophic drug developed by the Austrian pharmaceutical company Ebewe and used in Europe for treatment of head traumas, stroke and Alzheimer’s disease.
It is currently undergoing clinical trials in various countries as a treatment for slowing the progression of Alzheimer’s as well as other forms of cognitive impairment.
Cerebrolysin is designed to prevent some of the neurological damage linked to the development of senile dementia and Alzheimer’s by supporting the maintenance and growth functions of neurons.
It also has a positive effect on synaptic response sensitivity in the hippocampus which is the part of the brain where memories are stores. Due to its potential for improving brain function in healthy adults, many individuals have begun taking it off-label by purchasing this nootropic online.
What is the proper way to use this drug and what is considered a safe and effective Cerebrolysin dosage?
Brain Health
Cognitive Function
Memory- May decrease beta amyloid in the brain
- Promotes neuron health & plasticity
- May improve short-term memory
Cerebrolysin Review
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Cerebrolysin is a type of natural neuropeptide produced using purified porcine brain proteins and amino acids. These are small, biologically active brain proteins or peptides used by neurons to help them communicate with each other.
When Cerebrolysin reaches your brain, it has a neurotrophic effect and supports the many functions of your neurons, including stimulating the growth of new neurons in the dorsal root ganglia. It also aids in the maintenance of neurons that are part of the serotonin, choline and norepinephrine systems.
What makes Cerebrolysin so exceptional is that it is able to slow down the neuron damage that may be the root cause of Alzheimer’s. If administered when the disease is first detected, it could prevent the onset of further symptoms whereas most other drugs like Donepezil and Memantine only alleviate symptoms but cannot stop the progression of the disease.
So far, Cerebrolysin has been clinically tested on over 5,000 patients with Alzheimer’s in more than 80 trials around the world. Studies have found significant improvements in memory performance and cognitive function in as little as 4 weeks with results staying consistent even after 6 months of not using this drug.
It is already legal in several foreign countries, but has not yet been recognized and approved by the US government. For this reason, many people worried about age-related memory loss and cognitive decline have sought out buying Cerebrolysin vials from online pharmacies.
The product also appeals to nootropic users who are interested in cognitive enhancement and reviews say this drug is effective even in individuals who are healthy and do not show signs of brain impairment. It may contribute to better memory capacity and improved fluid intelligence among health adults.
Cerebrolysin for Vascular Dementia:
The main use of this drug right now is in the treatment of a condition known as vascular dementia.
Vascular dementia is wide-ranging classification of brain disorders that are often caused by inflammation or damage to the network of blood vessels which supply the brain.
People who suffer from this type of dementia (which can include Alzheimer’s disease) often experience difficulty in thinking quickly, concentrating, communicating, severe confusion, and may also have seizures.
There is no cure for vascular dementia, but we may be able to stem the development of this condition by taking preventative measures when signs are first detected or as an on-going life extension and anti-aging program.
Compared with standard care and medication, Cerebrolysin has been shown to dramatically improve symptoms related to this type of dementia. Research has indicated that it can boost brain function significantly, especially in the hippocampal region of the brain responsible for storing and retrieving memories.
Cerebrolysin patients have been observed to perform better on short-term recall, arithmetic, and other types of cognitive testing. Evidence also shows it may improve the overall mood of patients and contribute to better mental energy levels as well as ability to focus.
Current Cerebrolysin research looks at patients who have been involved in trials ranging from a few weeks to as much as three years, although there are a few long-term tests in the works as we speak. A recognized sign of Alzheimer’s disease is the build-up of a form of plaque in brain tissue. This plaque is known as amyloid-beta and it is present in large amounts when autopsies of individuals with Alzheimer’s are conducted.
Cerebrolysin is able to decrease the rate at which amyloid-beta is produced in the brain. By reducing the levels of this damaging substance, it is possible to prevent damage to brain cells that can impair memory and reasoning capacities.
Cerebrolysin injections may also slow down the natural rate of cell apoptosis or programmed cell death in the brain, enabling better memory storage and increased synaptic plasticity as you age.
Cerebrolysin Dosage & Use:
If you are looking at using Cerebrolysin, it is best to first speak to your doctor to determine whether this drug is appropriate for your needs. Even though Cerebrolysin is not currently sold in the USA, you may be able to find a local clinical trial that you can participate in or get your doctor to prescribe it on an off-label basis.
For those people taking Cerebrolysin for cognitive enhancement purposes as opposed to treating Alzheimer’s or other forms of memory loss, it is still important to check with your doctor and get advice on how to properly use this drug.
At present, you cannot take Cerebrolysin in pill or capsule format. It must be administered by injection which can make it more difficult to use than other nootropics or cognitive enhancement supplements.
The preferred administration method is on a 10 to 20 day course of therapy, with dosages of 5 to 30 mL per day. The doses are split into 5 mL ampules that you can take at several dosings per day.
Most nootropic users will only take a 5 mL Cerebrolysin dosage per day and see positive results even at this low level. Larger dosages are typically reserved for individuals with some recognized form of neurodegenerative disease or head trauma.
It can be safely administered in amounts up to 50 mL when used in an IV infusion, but this is strongly not recommended without medical supervision. In children, amounts of 1 – 2 mL are recommended, but you should not give it to a child without seeking advice from your physician.
It is also important to cycle your Cerebrolysin dosages according to a pre-set therapy schedule. Most people will take it for between 10 – 20 days, followed by a break of equal time length. Patients with Alzheimer’s may repeat this process several times.
Most studies use this over a period of four weeks and the have their subjects take a two month layoff, during which time the results are evaluated. Individuals interested in using Cerebrolysin as a cognitive enhancer will typically use it for 5 days straight, take two weeks off and then use it every two to three days for a week with two weeks off.
It is important to ensure the quality of this drug before administering it. Only use vials that have a clear, amber color and remove the solution from the packaging right before you inject it.
Cerebrolysin Side Effects & Safety:
Whenever taking an experimental drug, it is important to consider safety first and foremost. Cerebrolysin has received a clean bill of health so far. Over numerous studies, the researchers have been quick to point out that side effects are quite rare and mild when they do occur.
These can include headaches, nausea, dizziness, increased sweating and heat sensations. Side effects may be a reaction to the injection as opposed to a reaction to the effects of the drug. There have been more serious Cerebrolysin side effects reported, but most of these occur in rare cases and only when using higher dosages.
It has low risk of toxicity or contraindications and is well-tolerated in all types of users. Practicing caution with your Cerebrolysin dosages is the best way to prevent side effects and ensure that you can use this drug safely.
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- Zhang L, Chopp M, Meier DH, Winter S, Wang L, Szalad A, Lu M, Wei M, Cui Y, Zhang ZG. Sonic hedgehog signaling pathway mediates cerebrolysin-improved neurological function after stroke. Stroke. 2013
- Hartwig K, Fackler V, Jaksch-Bogensperger H, Winter S, Furtner T, Couillard-Despres S, Meier D, Moessler H, Aigner L. Cerebrolysin protects PC12 cells from CoCl2-induced hypoxia employing GSK3β signaling. Int J Dev Neurosci. 2014
- Muresanu DF, Ciurea AV, Gorgan RM, Gheorghita E, Florian SI, Stan H, Blaga A, Ianovici N, Iencean SM, Turliuc D, Davidescu HB, Mihalache C, Brehar FM, Mihaescu AS, Mardare DC, Anghelescu A, Chiparus C, Lapadat M, Pruna V, Mohan D, Costea C, Costea D, et al. A retrospective, multi-center cohort study evaluating the severity- related effects of cerebrolysin treatment on clinical outcomes in traumatic brain injury. CNS Neurol Disord Drug Targets. 2015
- Zhang Y, Chopp M, Meng Y, Zhang ZG, Doppler E, Winter S, Schallert T, Mahmood A, Xiong Y. Cerebrolysin improves cognitive performance in rats after mild traumatic brain injury. J Neurosurg. 2015
- Gauthier S, Proaño JV, Jia J, Froelich L, Vester JC, Doppler E. Cerebrolysin in mild-to-moderate Alzheimer's disease: a meta-analysis of randomized controlled clinical trials. Dement Geriatr Cogn Disord. 2015
- Ziganshina LE, Abakumova T. Cerebrolysin for acute ischaemic stroke. Cochrane Database Syst Rev. 2015
Article last updated on: March 13th, 2018 by Nootriment
5 Comments
Where can I buy cerebrolysin online? and in pills format, not vials.
you can’t, doesn’t exist in any other form yet
I am having Cerebroclyin for 5 days now 10 ml per day for sciatic nerve problem which effect my left feet and pain all over the leg with no results till know, although I am having a physiotherapy sessions 3 times per week for a period of two weeks.
By the way my doctor is consider one of the expertise worldwide.
Cerebrolysin is amazing. I have done 4 cycles of 5ml per day for 10 days.
I no longer need Mondafinal and using only a very small amount of other Nootropics is now considerably more effective than previous use of things such as Piracetam.
The results where immediate, with transitory effects being a tremendous feeling of well-being, sharper vision, clear mind, focus, mood enhancement.
The results built over each cycle and remain after the cycle ends. However, the transitory boost is only present for a few weeks after each cycle. Yet, this is not not the reason to take it. Even tho Cerebrolysin produces a powerful sense of well-being, its the lasting positive impact on all aspects of cognitive function that is the real motive for taking this amazing substance.
The injections are painless.
Immediate effects – onset within 5 mins build to peak in 3hrs, lasting 48hrs.
Enhanced cognitive function effects where noticed at 3 days. These continue to build with each cycle.
Its amazing to no longer need to take any other Nootropic. Also, when taking other Nootropics, now only a tiny fraction of the usual dose, gives a far greater effect.
If you choose to try this substance, make sure you take a break from ALL nootropics after each cycle to fully asses and appreciate the benefits.
cerebrolysin 1ml. how mush.