Anyone interested in using nootropic supplements to enhance their brainpower should consider taking some type of Choline powder.
In fact, adding Choline powder to a Nootropic stack may help make significant and lasting changes for individuals who want to improve their memory and cognitive performance.
This nutrient is important for many of your brain processes, however the average person often gets much less than the amount they actually need. It has been estimated at that much as 90% of humans are at least mildly deficient in choline.
Furthermore, almost every other nootropic works better when used in conjunction with a Choline supplement. There are a few different options available when deciding to buy Choline powder and you should take a look at how each of these versions work.
In this article, we will provide you with more information about the potential benefits of Choline, the risk of side effects, and recommended dosage and usage considerations.



- Supports memory and synaptic plasticity
- Raises acetylcholine levels
- Promotes brain health and focus
What Is Choline Powder?
Related Topics
- What is Choline?
- What is Acetylcholine?
- Cholinergic Receptors
- Choline's Role in the Brain
- Using Choline Supplements
- Cholinesterase Inhibitors
- Effects and Benefits
- Recommended Dosages
- Dietary Sources
- Choline Rich Foods
- Risks of Choline Deficiency
- Possible Side Effects
- Buy Choline
- How to Take Choline Powder
- Citicoline Review
- Choline Bitartrate Review
- Phosphatidylcholine Review
- Alpha GPC Choline
Choline is a water-soluble vitamin-like essential nutrient that is similar to the vitamin B family.
It is the main precursor molecule for the prominent neurotransmitter Acetylcholine which is involved in many different functions from memory to muscle control.
This substance must be consumed through the diet in order for the human body to remain healthy. Choline is also used to build the structural components of cell membranes.
Unfortunately, many new food and dietary recommendations have discouraged people from eating foods rich in this vitamin like egg yolks, fatty meats, and organ meats.
Choline powder is also considered to be an essential nutrient. This compound helps to prevent the condition known as fatty liver. In fact, one of the main functions of this nutrient is to allow cell membranes to operate with a high degree of flexibility in transmitting both water and fat soluble molecules.
This simply means that Choline improves the ability of fat-based nutrients to be transported into your cells and waste products to be passed out. Not only can this promote better whole body health, it also improves the membrane fluidity of your neurons which can slow down signs of aging on your brain.
How Does Choline Function in the Body?
Choline is a key component of many different structures in cell membranes. Without adequate supplies of Choline, the flexibility and integrity of cell membranes would either break down or become too rigid to allow essential chemicals and nutrients to flow in and out of the cells.
In addition to building structurally sound cells, Choline also acts as a direct precursor of Acetylcholine. This conversion into Acetylcholine is primarily responsible for most of the cognitive benefits associated with the supplement. Choline also helps to improve communication between nerves and neurons within the brain.
Some high quality choline powder is actually capable of directly crossing the blood-brain barrier. Once this occurs the supplement enters the central nervous system and begins having the desired effects.
At this point, it is also important to understand that Choline plays a role in methyl group metabolism. These methyl groups have a specific chemical structure that make many integral chemical events in the body possible through their transfer. Some examples are switching genes on and off and sending messages back and forth (somewhat similar to neurons).
Choline Powder Benefits
There are many benefits to Choline powder supplementation. Among the Nootropic-like benefits are an overall improvement of memory and learning capacity. Many users also report having a faster speed of recall and even expanded attention span. These benefits are possible due to the higher levels of Acetylcholine in your brain which results in more stimulation of your neurons.
As your neurons are made more active and can communicate to each other at a faster rate, this has the effect of making your thoughts seem like they flow better and experiencing greater access to your stored memories. Another common thread in Choline powder reviews is the experience of more mental power, accompanied by improved focus and greater concentration.
The benefits are not limited to Nootropic effects: choline may also lessen chronic inflammation. This in and of itself is critical since inflammation has been linked to a wide variety of diseases like heart disease, osteoporosis, type 2 diabetes, Alzheimer’s and other cognitive impairments. There is also some evidence that Choline helps to reduce oxidative stress.
Research on supplemental Choline use is promising, but limited, and more large-scale human trials are needed to determine the full effects supplemental Choline may have in the body. At this time, Choline is available in the USA only as a health supplement, and the FDA has not approve Choline as a drug to prevent or treat any conditions.
Choline Dosage
Proper dosage of a supplement depends on many factors including age, weight, and personal sensitivities.
The below dosage recommendations are general guidelines only and your personal dosage may be different. It is always recommended that you speak with your doctor before beginning any new supplements to help determine the best dosage for your needs.
The adequate daily intake of Choline was set in 1998 at 425 mg per day for woman, and 550 mg per day for men. Of course, many people today who are looking for Nootropic-like effects often take more.
Among Nootropic users, the generally accepted range is anywhere from 500 mg to 3 grams if you are using a Choline powder supplement like Choline Citrate, Choline Bitartrate, or Choline Chloride.
Should you decide to buy one of the more powerful cognitive enhancers such as Citicoline Powder or Alpha GPC powder, you will need much less to see desired effects.
Choline has been rated by the Natural Medicines database as Likely Safe when used orally and appropriately. Choline powder is generally well-tolerated and for most people some experimentation to determine the perfect dosage level will not cause negative effects.
Some side effects have been reported, often when very high dosages (more than 3.5 g per day) are taken, including low blood pressure, nausea, vomiting, diarrhea, constipation, dizziness, excessive sweating, insomnia, and headache.
The best way to use Choline is as the base of your Nootropic supplementation program. In other words, start with the Choline first and then add on other brain boosters with complementary effects.
Some excellent choices for Choline supplements include Alpha GPC, CDP Choline, and Centrophenoxine. From here, you could consider adding one (or more) of the Racetams, depending upon the goal of your overall program.
You may also want to consider Huperzine which is another Nootropic that can increase Acetylcholine levels with a slightly different method of action.
Also bear in mind that if you are taking other Nootropic supplements, a sharp increase or even decrease in your Choline powder dosage might have some unintended effects such as headaches.
The best course of action is to always start with a small dose of Choline powder and then increase gradually as you become more familiar with the actual effects.
- Blake MG, Boccia MM, Krawczyk MC, Delorenzi A, Baratti CM. Choline reverses scopolamine-induced memory impairment by improving memory reconsolidation. Neurobiol Learn Mem. 2012
- Corriveau JA, Glenn MJ. Postnatal choline levels mediate cognitive deficits in a rat model of schizophrenia. Pharmacol Biochem Behav. 2012
- Gonzales MM, Tarumi T, Kaur S, Nualnim N, Fallow BA, Pyron M, Tanaka H, Haley AP. Aerobic fitness and the brain: increased N-acetyl-aspartate and choline concentrations in endurance-trained middle-aged adults. Brain Topogr. 2013
- da Silva RP, Kelly KB, Lewis ED, Leonard KA, Goruk S, Curtis JM, Vine DF, Proctor SD, Field CJ, Jacobs RL. Choline deficiency impairs intestinal lipid metabolism in the lactating rat. J Nutr Biochem. 2015
- Fischer V, Both M, Draguhn A, Egorov AV. Choline-mediated modulation of hippocampal sharp wave-ripple complexes in vitro. J Neurochem. 2014
- Mills JL, Fan R, Brody LC, Liu A, Ueland PM, Wang Y, Kirke PN, Shane B, Molloy AM. Maternal choline concentrations during pregnancy and choline-related genetic variants as risk factors for neural tube defects. Am J Clin Nutr. 2014
- Zeisel SH. Metabolic crosstalk between choline/1-carbon metabolism and energy homeostasis. Clin Chem Lab Med. 2013
- Traini E, Bramanti V, Amenta F. Choline alphoscerate (alpha-glyceryl-phosphoryl-choline) an old choline- containing phospholipid with a still interesting profile as cognition enhancing agent. Curr Alzheimer Res. 2013
Article last updated on: March 13th, 2018 by Nootriment
1 Comment
I’m justt starting out using nootropics.I’m actually still waiting on my order to come in the mail.And I been looking over and reading this site.And I seen an area the offers free samples. Where do I found the form for that.? Or what do I have to do to get said samples? I’m going to keep looking around but, just in case please contact me at [email protected] to info me. Thank You David