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Using Cissus quadrangularis for weight loss and weight management has been demonstrated as effective in some human research trials.
This supplement has been observed to decrease body fat composition, decrease waist circumference, improve blood sugar control, and reduce appetite in humans.
It may also reduce the absorption of fats and carbohydrates, blocking these calories from entering the blood stream through the intestines.
Cissus quadrangularis supplements may further increase lean muscle mass and promote muscle building, helping to support increased metabolism.
Bone Health
Bodybuilding
Weight Loss- Promotes joint health & pain reduction
- Sedative & muscle relaxing properties
- Supports weight loss & workout recovery
Top Cissus Products* ❯What is Cissus Quadrangularis?
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Cissus quadrangularis (CQ) has been utilized by African and Asian cultures for more than one thousand years for bone disorders and to stimulate the metabolism.
CQ affects gene transcription processes which switch on the mechanisms which accommodate the proliferation and differentiation of osteoblasts (cells from which bones develop).
Using Cissus has been found to stimulate bone growth in animal studies, improve bone thickness, and may help to prevent osteoporosis.
As a metabolic enhancer, CQ balances bacterial function in the intestinal tract, leading to overall improvements in digestive efficiency. Research shows that it may block carbohydrates and fats being absorbed from foods that we eat by inhibiting the digestive enzymes amylase and lipase.
This means that CQ may prevent some of the calories you consume from being absorbed into your body. This may make it easier to lose excess weight and maintain a sustainable, healthy weight. CQ may also help to remedy other conditions that begin with digestive imbalances; including hemorrhoids, asthma, peptic ulcers, chronic constipation and more.
Cissus Quadrangularis for Weight Loss
Maintaining healthy digestive tract conditions is integral for reaching and then sustaining weight loss goals. More than one-third of Americans are now classified as obese and/or overweight. Also, more than one-third of Americans are classified as “completely sedentary” by the CDC.
Poor food choices, excess food portion sizes and lacking physical activity levels, are causing record high levels of health problems and diseases, including metabolic syndrome and obesity for instance.
There is no supplement that can correct for these underlying factors of obesity. However, supplements like Cissus Quadrangularis may be able to support weight loss efforts by helping individuals control their appetite and by blocking the absorption of some fats and carbohydrates. CQ may enhance the effects of eating a healthy diet, choosing sensible portion sizes and getting sufficient exercise.
In research trials, administering CQ to obese adults has resulted in statistically significant weight loss. One randomized, double-blind, placebo-controlled study looked at the combination of Cissus quadrangularis with White Kidney Bean Extract for weight loss over a 10 week period.
The study found that administering CQ or a CQ/WKB combination twice a day before meals resulted in noticeable differences in weight loss after four weeks compared to a placebo group. These results continued to increase over the remainder of the trial period, with the combination of Cissus quadrangularis and White Kidney Bean resulting in the greatest total weight loss.
In another study, 123 overweight participants were given CQ for eight weeks. After the eight week treatment period, the groups given CQ saw significant reductions in body weight, fasting blood glucose measurements, cholesterol levels, triglycerides and C-reactive protein.
The researchers concluded that supplement formulations with Cissus Quadrangularis for weight loss can be effective and that this supplement may help control many factors related to metabolic syndrome.
Lipopolysaccharide (LPS) Balancing
Cissus quadrangularis seems to work for weight loss via several different mechanisms of action. Known effects of this supplement include:
- Reducing intestinal inflammation;
- Regulating the balance of gut bacteria;
- Improving antioxidant-based immunological defenses
CQ has been shown in clinical tests to exhibit antibacterial properties. It shows action against the Staphylococcus bacteria family, a group that is commonly found in exaggerated levels in obese individuals. When gut bacteria is not properly balanced, an overproduction of lipopolysaccharides is likely.
Because LPS agents break down the structural membranes that keep bacterium alive, LPS surpluses are toxic and can cause metabolic insufficiencies. When an individual is unable to efficiently deal with the foods he or she ingests, numerous issues related to weight control become possible. CQ is known to inhibit the overproduction of LPSs and thereby reverse digestive issues associated with elevated LPS levels.
Further, C. quadrangularis has been shown to be effective at reducing the synthesis of inflammatory nitric oxide (iNO). It also acts against the successes of NF-kappaB, a primary gene signaling substance that induces generalized inflammation.
Cissus Quadrangularis for Liver Function
To further aid in the weight loss process, CQ supports detoxification via improved liver health and functioning. It has been shown clinically to reduce free radical damage caused by TB drug therapy.
This aids weight loss goals because the liver is often the target for radical oxygen-synthesizing and inflammation-inducing challenges stemming from the adipose tissue (fat) and the digestive tract itself.
When the liver functions better, toxins are better dealt with and eliminated. Bodily systems are then able to perform their duties more effectively, with less energy expenditure. This leads to general health improvements over time; specifically an enhanced ability to break down, assimilate and utilize foods – and then to efficiently expel the wasteful byproducts.
The results of many CQ research studies are very promising, however more human trials still need to be done to fully understand how this compound works in the body, and all of the weight loss effects CQ may have. At this time, Cissus is available in the US as a supplement only, and the FDA has not approved Cissus quadrangularis as a drug to prevent or treat any conditions.
Cissus Quadrangularis for Weight Loss: Conclusion
Research into C. quadrangularis continues to provide promising clinical evidence for weight loss and the management of metabolic syndrome. Despite the effectiveness of Cissus quadrangularis for weight loss, it is not enough by itself.
Maintaining a healthy weight level requires adopting a healthy lifestyle by making the right food choices and exercising regularly. Using a diet pill like CQ may result in short-term weight reduction, but to sustain this result, diet and fitness must play a part. Always consult with a doctor before beginning to use Cissus quadrangularis, or any other type of supplementation.
Article last updated on: May 5th, 2018 by Nootriment