Cognizin Citicoline is one of the best-selling brands of CDP Choline supplements.
Why do people take a brain supplement like Cognizin Citicoline?
This nutritional brain booster is sought out by students who want better grades in school, parents who want to help their kids focus better, and older individuals who want to keep their memory function high.
While the brain only makes up about two percent of your body weight, it consumes over twenty percent of the body’s energy while at rest. The brain demands a lot of nutritional support in order to keep even the average person alert and focused throughout the day.
Not to mention the fact that modern life places a tremendous amount of pressure on our brains due to stress (oxidative and otherwise), lack of exercise, poor diets, etc.
Cognizin Citicoline is designed to provide the brain with the vital nutrients it needs to stay sharp and function properly.
In this review, we will take a closer look at the effects of CDP Choline as well as dosing and proper use of this supplement.



- Supports memory, focus & mental clarity
- Increases levels of acetylcholine neurotransmitter
- Promotes brain cell health & communication
Cognizin Review
Related Topics
- What is Citicoline?
- Cytidine Diphosphate Choline
- CDP Choline Effects
- User Reviews
- Benefits for the Brain
- Comparison to Alpha GPC
- Risk of Adverse Effects
- Safe Dosage Guidelines
- How to Take
- Stacking with Piracetam
- Buy CDP Choline
- Supplement Ratings
- Ceraxon Citicoline
- Cognizin Citicoline
- Neuroaxon Citicoline
- Somazina Citicoline
- Zynapse Citicoline
Cognizin Citicoline is a scientifically proven brain nutrient that helps to improve memory and enhance overall cognitive function.
In addition to the very promising scientific research, there are many positive Cognizin Citicoline reviews that speak to the benefits of this compound.
Citicoline is a natural precursor to one of the most important neurotransmitters in the brain called Acetylcholine. Most people actually have lower Acetylcholine levels that what is ideal for optimal intellect and cognition.
By taking a choline source like Citicoline, you can ensure that your brain is properly supplied with enough Acetylcholine to regulate the many millions of transmissions that occur between your neurons every moment.
Cognizin Citicoline has a reputation for being a high-quality source of Choline, but there are other options to consider as well. In fact, you may find it much cheaper to buy a generic version of Citicoline in powdered formulation rather than spending extra on the brand name.
Cognizin Citicoline Methods Of Action
As you age, your brain naturally produces less energy over time due to many different factors. It is believed that Cognizin Citicoline may slow or reverse this decline by improving some of the basic metrics of neuron health.
Citicoline works to increase the activity of the mitochondria in brain neurons. These mitochondria are the energy producers located within each cell. The supplement also has been shown to increase levels of ATP (which is the essential energy component that is produced by the mitochondria).
With better energy supply, you may experience more clarity of thought, and mental processes involved in memory, learning, and reasoning become more efficient.
Cognizin Citicoline also is effective at increasing the levels of several different neurotransmitters within the brain.
As mentioned previous one of these neurotransmitters is Acetylcholine, a key player in memory formation and storage. Acetylcholine is specifically implicated in synaptic plasticity which is a measure of your brain’s ability to form new connections and increase communication between neurons.
Decreasing levels of this neurotransmitter throughout our lives is thought to be a major reason why older people lose memory function. It is believed that in some severe cases, Alzheimer’s may result from very low levels of Acetylcholine availability.
This supplement has also been shown to increase the levels of Dopamine and Norepinephrine. These are both key neurotransmitters related to mood and mental energy.
Dopamine is thought to help control areas such as mood and movement. Increases in this substance often lead to feelings of well-being and even pleasure. Additionally, it is a key player in helping to cement new memories and learning experiences. Norepinephrine is involved in the fight or flight response associated with the adrenal glands.
Cognizin Citicoline can also enhance the synthesis of phospholipids within your cerebrum. These are key components of cell membranes, especially neurons and other specialized brain cells. This helps to improve brain communications since they also serve as key conductors in the transmission of nerve impulses.
Another benefit of this improvement is the promotion of overall brain metabolism leading to better neural health and possibly even slowing down signs of aging.
Cognizin Citicoline Benefits
Supplementation with Citicoline can lead to a range of benefits for your mental performance.
This includes improved short and long-term memory, attention, perceptual-motor capacity, and even behavioral and emotional control in older adults suffering from cognitive impairment.
Of course, this supplement will also benefit younger and healthier adults. This also includes an increase in memory and even learning capacity.
There are a number of students who actually use Citicoline to help them study and understand what they are learning with greater ease. Many users also experience greater memory consolidation and recall in different areas including auditory, visual and spatial memory storage.
Brain energy may also be increased with Cognizin Citicoline. This effect can sometimes be quite dramatic. It will lead to an enhanced attention span along with greater ability to focus and concentrate.
In a number of cases this can also produce increased sensory perceptions, especially related to better visual acuity (colors become richer, deeper, and more vibrant).
There are a number of clinical uses for this supplement. This includes helping to treat people who are suffering from conditions of low oxygen levels.
A recent Italian study has also shown that the supplement was able to significantly reduce the progress of glaucoma as well as protect the nerves surrounding the eyes.
Citicoline was originally developed for the treatment of stroke. There is evidence that Citicoline taken daily may improve memory and behavior in patients with chronic cerebrovascular disease, such as stroke. Some researchers have even demonstrated a link between lower risk of stroke and Citicoline supplement usage.
It may also help in the treatment of a number of age-related cognitive degeneration issues. The Natural Medicines database has rated Citicoline as Possibly Effective for improving age-related cognitive impairment. One study found that in people aged 50-85 with poor memory, use of 1000-2000 mg of Citicoline daily seemed to improve verbal memory.
Research on Citicoline has been very promising, however more studies, especially large-scale human trials, are still needed to full understand all of the benefits of Citicoline. At this time, Citicoline is available as a health supplement only, and the FDA has not approved Citicoline as a drug to prevent or treat any conditions.
Should you Use Cognizin Citicoline?
Developing a sharper brain is possible at any age. Whether you are currently in school, are in your early adulthood, or are closing in on your senior years, a daily dosage of Citicoline may help you increase your cognitive power.
If you are experiencing more and more ‘senior moments’ it does not have to continue this way. There are numerous reviews and user reports showing that Citicoline has been tremendously beneficial for overall brain health and led to significant improvements in some users.
Many of these people were concerned about the onset of Alzheimer’s disease or even dementia. There have also been studies to support the fact that Cognizin Citicoline is indeed able to improve overall brain energy and improve the speed of many cognitive tasks.
As your brain health improves, you may start to notice improvements across many different areas of your life. Most people report that Citicoline benefits start with increased clarity and mental alertness. It may even seem as if a fog has been lifted from your brain. You may start to feel more motivated and become more productive at your work or business.
If you have never used a brain supplement or a “nootropic” before, it may be surprising that all of this is possible from a natural compound like Citicoline.
You can find Cognizin Citicoline in a number of different health products or you can buy pure Citicoline powder online for the best results at the best value.
- Dávalos A, Secades J. Citicoline preclinical and clinical update 2009-2010. Stroke. 2011
- Gutiérrez-Fernández M, Leciñana MA, RodrÃguez-Frutos B, Ramos-Cejudo J, Roda JM, DÃez-Tejedor E. CDP-choline at high doses is as effective as i.v. thrombolysis in experimental animal stroke. Neurol Res. 2012
- Bagdas D, Sonat FA, Hamurtekin E, Sonal S, Gurun MS. The antihyperalgesic effect of cytidine-5'-diphosphate-choline in neuropathic and inflammatory pain models. Behav Pharmacol. 2011
- Qian K, Gu Y, Zhao Y, Li Z, Sun M. Citicoline protects brain against closed head injury in rats through suppressing oxidative stress and calpain over-activation. Neurochem Res. 2014
- Turkkan A, Alkan T, Goren B, Kocaeli H, Akar E, Korfali E. Citicoline and postconditioning provides neuroprotection in a rat model of ischemic spinal cord injury. Acta Neurochir (Wien). 2010
- Parisi V, Manni G, Colacino G, Bucci MG. Cytidine-5'-diphosphocholine (citicoline) improves retinal and cortical responses in patients with glaucoma. Ophthalmology. 1999
- Killgore WD, Ross AJ, Kamiya T, Kawada Y, Renshaw PF, Yurgelun-Todd DA. Citicoline affects appetite and cortico-limbic responses to images of high-calorie foods. Int J Eat Disord. 2010
- Kaplan T, Kafa IM, Cansev M, Bekar A, Karli N, Taskapilioglu MO, Kanar F. Investigation of the dose-dependency of citicoline effects on nerve regeneration and functional recovery in a rat model of sciatic nerve injury. Turk Neurosurg. 2014
Article last updated on: April 6th, 2018 by Nootriment
2 Comments
Dear sir,
we have need citicoline in bulk amout. can you provide this.and plz share ist spec of your product.and which pharmacopoeia grade..
Hi Kapil,
I would recommend Nootrico if you are looking to purchase Citicoline powder :).