Cordyceps extract is derived from a genus of mushrooms containing over 400 species of fungi.
Various species of cordyceps have been used for thousands of years in traditional medicine systems, particularly in Tibet and China.
Although hundreds of species of the cordyceps are known, two species are most commonly supplemented: Cordyceps sinensis and Cordyceps militaris.
The extracts of these mushrooms are purported to have significant health-boosting properties in Traditional Chinese Medicine and are used today to support the immune system.
Like all species in the genus, both C. sinensis and C. militaris are parasitic, meaning they require a host organism to survive and will damage and eventually kill the host. For example, C. militaris lives on caterpillars and some other arthropods, feeds off the organism, and will eventually kill the organism and release a mushroom or fruiting body.
The end result is a part-fungus, part-arthropod substance that is often ground into powder and used as a routine dietary supplement. Although cordyceps mushroom extract is often consumed for its purported health benefits, there is currently insufficient evidence to support its clinical application.



- Shown to reduce fatigue & stress
- Anti-oxidant that stimulates the immune system
- Increases testosterone secretion & libido
Medicinal Properties of Cordyceps Extract
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The full therapeutic potential of cordyceps continues to be investigated. High-quality cordyceps extracts are being examined to understand their medicinal properties.
No placebo-controlled double-blind human trials have been conducted so far.
In laboratory and animal tests, components of cordyceps have been observed to:
- Exhibit antitumor, antimetastatic, antiproliferative, antileukemic and chemopreventive effects;
- Act as an antioxidant, anti-inflammatory and anti-aging agent;
- Function as a vasodialator, decreasing blood pressure;
- Exhibit hepatoprotective, neuroprotective, renoprotective and pneumoprotective effects;
- Act as an treatment for lethargy;
- Act as an antimalarial, antibacterial, antifungal, antimicrobial, antiprotozoal and antiviral compound;
- Support the immune system;
- Help modulate blood sugar levels
The medicinal properties of Cordyceps sinensis or Cordyceps militaris have yet to be studied in a clinical setting. Further research is necessary before any conclusions can be drawn about the therapeutic effects. However, the long history of traditional use by natural health practitioners is a testament to the purported effectiveness.
Benefits of Cordyceps Extract
One area of continued interest for researchers and consumers alike is the anti-cancer effects of Cordyceps mushrooms.
Cordyceps extracts have been observed to have the following effects on cancer cells in laboratory experiments:
- Increase the synthesis of cytokines, including: interleukin, growth factors and interferon;
- Improve tumor cell cycle arrest and cell death;
- Reduce tumor size, inhibit tumor progression and extend survival times;
- Improve immune system response to radiation treatments and chemotherapy;
- Lessen the damage sustained from chemotherapy and radiation;
- Increase superoxide dismutase (antioxidant) levels in plasma;
With regards to cardiovascular health, Cordyceps extracts have been observed to:
- Reduce triglycerides and LDL cholesterol levels in the blood;
- Restore proper cardiac functioning in arrhythmia subjects;
- Decrease cardiac oxygen consumption;
- Induce vasorelaxation to the endothelium of the heart muscle and blood vessels;
There are also benefits reported for the management of Diabetes Mellitus and for reduction of diabetes risk factors.
Cordyceps extracts have been observed to: increase the utilization of glucose, decrease the amount of free glucose in the blood, and increase leptin and insulin sensitivity. By helping to manage blood glucose levels, Cordyceps may also support weight loss.
Cordyceps are also being investigated for other therapeutic effects, including: improving sexual performance in the elderly; protecting and enhancing liver function; and increasing the phagocytosis of macrophages. Effects are said to be improved when used in conjunction with reishi mushroom extract.
How to Use Cordyceps Extract
The best dose of cordyceps extract will depend on several factors. Current daily doses range between 3 and 8 grams. Variables like current health, targeted benefits, diet and activity level are all relevant. Follow the instructions of the manufacturer of the supplement you are using.
Cordyceps has played a role in many long-established medicinal systems and are not generally associated with severe side effects. Cordyceps mushrooms are generally well tolerated by humans.
In mouse tests, as much as 80 grams per kilogram of bodyweight have been administered without inducing death. In humans, certain mild and often quickly passing side effects have been reported, including diarrhea, dry mouth and stomach upset.
Certain groups should avoid supplementation. For instance, pregnant women and new nursing mothers should not use cordyceps mushrooms because there is insufficient evidence to determine if it is safe for the fetus. Also, patients scheduled for surgery within two weeks time should discontinue cordyceps supplementation.
Cordyceps capsules may impact blood sugar levels and should be used with caution by anyone with prediabetes or diabetes mellitus type II. Cordyceps has been observed to have immunomodulating properties and should also be used with caution by anyone with a disease related to the immune system.
C. militaris is known to adversely interact with prescription medications for kidney disease, liver disease and immune system disorders. The immunomodulating effects of cordyceps can cause ineffectiveness, or hyper-effectiveness of such drugs.
Always consult with a physician is you are considering cordyceps extract supplementation. Be sure to ask direct questions about possible interactions between C. militaris and any prescription and/or over-the-counter drugs you may be taking.
- Panda, Ashok Kumar, and Kailash Chandra Swain. "Traditional Uses and Medicinal Potential of Cordyceps Sinensis of Sikkim." Journal of Ayurveda and Integrative Medicine 2.1 (2011): 9–13. PMC. Web. 22 June 2015.
- Yue K1, Ye M, Lin X, Zhou Z. The artificial cultivation of medicinal Caterpillar Fungus, Ophiocordycepssinensis (Ascomycetes): a review. Int J Med Mushrooms. 2013;15(5):425-34.
- Paterson RR. Cordyceps: a traditional Chinese medicine and another fungal therapeutic biofactory? Phytochemistry. 2008 May;69(7):1469-95.
Article last updated on: May 4th, 2018 by Nootriment