Cylert Review: Effects, Side Effects and Dosages for ADHD

Cylert is also known as Pemoline and used under the brand names Betanamin, Tradon, and Ceractiv.

It is considered to be a stimulant and classified as an oxazoline (compounds which contain a single atom of nitrogen and oxygen together to preserve carboxylic acids).

This substance was first synthesized in 1913 although its activity or action was not uncovered until the 1930’s. This drug has also been primarily used within the United States as a treatment for ADHD and narcolepsy.

At the moment it falls under the definition of a psychotropic and as such is a Schedule IV drug within the US.

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Cylert Effects:

Although the exact mechanisms of action for this drug are not fully understood it is considered to be an effective and powerful central nervous system stimulant.

Its pharmacological activity appears to be similar to that of other known stimulants. However, instead of operating in a dopaminergic fashion, Cylert appears to be dopamimetic in nature, imitating the effects of your natural circulating Dopamine.

This pharmaceutical appears to act as a sort of ‘surrogate’ for the neurotransmitter Dopamine. In other words, it does not affect endogenous intracellular Dopamine levels.

This is also likely why it does not have many sympathomimetic side effects which typically consist of dry mouth, loss of appetite, faster pulse, cardiac stress, higher blood pressure as well as dilated pupils.

Cylert Benefits:

This drug has been primarily used as a treatment for ADHD in children and even narcolepsy.

However, since 2005, the use of this supplement as a treatment for ADHD, especially in children, has been discontinued and the remaining supplies on the market are ‘discouraged’ from being prescribed by physicians for such treatment by the FDA.

On the other hand, Cylert is sometimes still used to help in cases of adult ADHD.

Another potentially interesting benefit of this supplement is as a Nootropic agent. The name Nootropic itself comes from the Greek language and means ‘affecting the mind.’

Noopept effects are generally related to things such as improvements in memory, attention, and other cognitive processes.

There is certainly some evidence here to suggest that Cylert may act as what is called a catalyst conductor in brain centers related to memory.

This helps to raising the efficiency of memory formation and the speed of recall along with assisting the formation of RNA in the brain. It may also serve to improve attention spans and attention-switching tasks along with increased concentration and focus.

Cylert Dosage:

When this drug was still readily available on the market, it came as tablets of 18.75 mg, 37.5 mg, or 75 mg. The most recommended method of administration was once daily, usually in the morning.

It should be emphasized that is not something recommended for self-administration, it should only be purchased under the care and advice of a qualified medical professional.

The recommended starting dose is a single 37.5 mg pill daily. Under careful observation, this dose may be increased as the supervising physician deems appropriate. Normal daily dosage ranges for most people fall between 56.25 and 75 mg. Doses above 112.5 mg are potentially dangerous and not recommended.

This is generally good advice for any new nootropics or other supplements – starting with a lower dose and then only increasing once benefits and effects have presented and it is possible to determine the proper course of action.

Cylert Side Effects:

There have been some side effects associated with Cylert. It is definitely not for everyone. The most commonly reported of these side effects include irritability and insomnia. In some cases, users may experience headaches, nausea, hallucinations, liver irritation, increased heart rate, and the worsening of tics and Tourette’s Syndrome.

It should be noted that among the major concerns of the FDA in 2005 about this supplement was the potential for liver issues. In fact, this was the primary reason stated for their decision to discontinue the drug. People who have or had a history with liver disease or kidney disease, seizures, Tourette’s Syndrome, epilepsy or a history of drug and/or alcohol addiction should not take this be.

There have been known cases of Cylert leading to liver damage which resulted in a transplant and/or death.

If you notice anything such as unusual fatigue, yellow skin or eyes, itching, clay-colored stools, or dark urine these should be reported immediately as this could be early warning signs of liver disease.

Cylert Review:

While Cylert may be a relatively effective treatment for ADHD, it does appear to come along with some significant risks as well.

These side effects should not be taken lightly. For someone who is simply looking for the Nootropic benefits, there are clearly many better options available.

The same thing for both children and adults seeking help with conditions of ADHD or narcolepsy. This is probably a drug with an overall poor risk to reward profile.

What are some of the safer nootropic alternatives that you should consider instead? In order for a supplement to be classified as a nootropic under the official definition, it has to be non-toxic and actually offer neuroprotective benefits to your brain cells.

Many nootropics can boost Dopamine activity without contributing to the negative side effects of Cylert.

Some of the best Dopaminergic nootropics include Aniracetam, Theanine, Tyrosine, Phenylalanine among many others.

These nootropics work to enhance your mood, help you focus and increase overall cognitive abilities in areas such as memory, learning, reasoning, motivation and brain energy metabolism.

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