D-ribose Reviews, User Experiences & Clinical Research

More than 300 D-ribose studies have shown it to be effective for treating and reversing the symptoms of chronic fatigue syndrome (CFS), fibromyalgia syndrome (FMS) and various other conditions.

D-ribose reviews from users also demonstrate the effectiveness of this supplement for boosting energy levels and increasing athletic power output.

This supplement is used by bodybuilders and athletes for better endurance, shorter recover times and to combat fatigue.

It also has a number of cardioprotective properties, preventing oxidative damage and improving the function of the heart muscle in certain patients. In one study, taking D-ribose supplements was found to improve the quality of life for patients experiencing fatigue.

D-Ribose

Energy Supplement

Fatigue

Exercise Capacity

Workout Recovery

How It Works:

• Helps increase ATP production for energy
• Cardioprotective & decreases fatigue
• Improves workout recovery time & output

Dosage:

Between 5 - 20 g per day

Safety:

Rated Likely Safe

Top D-Ribose Products* ❯

View User Ratings* ❯

D-ribose Review

D-ribose is a pentose monosaccharide that occurs naturally and is also synthesized in our bodies within the musculature system.

It is an important component of ATP, which is the primary energy storage molecule found in the human body.

D-ribose binds to nucleic acids to synthesize energy intermediates in the forms of adenosine triphosphate (ATP), flavin adenine dinucleotide (FADH) and nicotinamide adenine dinucleotide (NADH).

It also serves as a structural constituent of RNA and DNA. As such, D-ribose is known to affect energy synthesis and metabolic processes on many levels. It has a number of medicinal uses as well as health-boosting effects when taken as a dietary supplement.

D-ribose reviews suggest that doses between 5 – 15 grams per day are effective. Current scientific research continue on D-ribose supplements to determine its full range of therapeutic effects.

User Experiences with D-ribose Powder

User reviews of D-ribose posted on Amazon are generally positive, with one product receiving a 4.4 out of 5 score, based on 138 reviews. 83% of users gave this supplement a 4 or 5 star review, with only 10% scoring it a 1 or 2.

Reviews describe increased energy levels, improved control of symptoms from fibromyalgia, enhanced mental alertness and improved stamina. Below are some comments from user reviews:

Have chronic fatigue and sometimes this is all that gets me through the day. Tried Now brand, also a good value but this one mixes and tastes better. Both help with energy. Started with 2 scoops/day for 2 months and reduced to 1/day. Have read it dies not work for everyone and that some people don’t need to continue indefinitely as I do. On bad days I increase the dose. – Anonymous

I have fibromyalgia, read about D-Ribose and I’ve been taking it for over 6 months. It truly does help with fatigue and mental hiccups. Buy it in powder form for the best value. I stir it up in my morning orange juice. I take around 20 grams a day, 10 at the very least. The price is usually the same with any mfg, but if you shop around you can get free (amazon prime) shipping and save a bit of money. Basically, it costs around $30 a month for D-Ribose — regardless of where or who you buy the powder from… – TheAssemblagist

I have fibromyalgia with fatigue syndrome and I would have only 2, maybe three days a year that I would feel “normal” and able to function. I feel so much better with D-Ribose and I am able to function. My husband noticed that I have been feeling a lot better and I have been able to do a lot more than usual after just one month’s use. I noticed the difference after one use. I do love it! And there are no side effects. – CRM

I have been using this in my coffee for years. It really helps with the premature muscle fatigue and muscle pain that comes along with fibromyalgia. – J. Thomas

WOW and THANK YOU for giving me my life back. I now have bought this 3 times for myself and 5 times as gifts for other friends and family members that are either sick with chronic fatigue or fibromyalgia or dysautonomia like myself. It’s just amazing the difference in me. I am so happy to finally find something that truly works. – kimcarver

I am 70 years old and still lifting weights five days a week. I added this to my routine about three months ago, and I have noticed a pretty definite improvement in stamina, recovery, and strength. Highly recommend this product. – jbosman

Use it as a supplement for muscle strength after strenuous exercise. Renews my energy after strong workout. I feel totally renewed, – T. K. Zoubul

How Does D-Ribose Work?

D-Ribose works to improve the energy production within your cells, helping to alleviate symptoms of chronic fatigue syndrome and fibromyalgia.

Mitochondria are specialized cell components that generate about 90% of the total energy needed by the body for cellular metabolism. All cells except for erythrocytes (red blood cells) contain mitochondria.

When mitochondria are unable to function properly, numerous diseases can result. This causes less energy to be synthesized within each cell, and this leads to performance issues as cells incur damages and die off.

As this cycle of cellular injury and death repeats chronically, entire organs and body systems may begin to function weakly, or fail altogether. Overall quality of life is greatly affected as mitochondrial dysfunction and disease causes damage to the muscles, kidneys, heart, brain, liver, respiratory system and/or endocrine system.

Some of these conditions may be linked to inadequate supplies of D-Ribose. More specifically, the following effects and conditions may onset:

• Lessened motor control;
• Pain, stiffness, soreness and/or weakness in the muscles via lactic acidosis;
• Digestive disorders and issues with urination/defecation;
• Problems with swallowing;
• Stunted growth and/or poor repair/healing capacities;
• Cardiac failure and/or heart disease;
• Liver and/or kidney disease;
• Diabetes mellitus;
• Complications with respiration;
• Issues with sight and hearing;
• Increased susceptibility to bacterial and/or viral infections;
• Seizures and convulsions.

D-ribose Effects on the Heart

For decades, D-ribose has been studied; addressing its potent effects on improving heart functioning, especially in subjects afflicted with coronary artery disease, congestive heart failure, and a condition of weak heart muscle tissue called cardiomyopathy.

Unhealthy heart muscles, like all unhealthy muscles, result from being starved of energy.

When ATP energy is lacking in the heart muscle, the tissues cannot fully relax between contractions. This occurs because it actually requires more energy for the heart muscle to relax than it does for it to contract. This means the heart cannot fully fill with blood, and less blood is delivered with each beat.

Less blood delivered equals less oxygen, other nutrients, hormones and other vital blood-riding substances delivered throughout the bodily systems. Because it cannot relax, the heart stiffens and becomes less efficient. Hypertrophy (enlargement) of the heart often results and the heart becomes increasingly less able to perform.

Similar to a bodybuilder repetitively forcing his muscles to grow via increased resistance, the heart muscle grows in the same way because of the extra strain put upon it by the inability to relax.

The stiffening and hypertrophy of the heart can be deadly; not desirable like the growth of a bodybuilder’s pectoral muscles. Lethargy, apathy, pain, fatigue, brain fog, demotivation and/or depression may result.

To prevent and treat these possible symptoms, adequate ATP synthesis must be accommodated. D-Ribose is able to improve ATP synthesis and is a key component in the pathways used to generate this form of stored energy.

With ATP available in the heart muscle, it is able to fully relax between beats and thereby deliver increased amounts of blood throughout the circulatory system. In order for the heart muscle to remain subtle and elastic, and thereby accommodate adequate blood flow, enhanced energy synthesis is necessitated.

D-ribose Research

In addition to positive user reviews, D-ribose has been the subject of extensive clinical trials demonstrating positive effects. In one recent German study, 10 grams of D-ribose supplement given daily for three weeks induced significant improvements in all aspects of diastolic heart performance.

Increased ATP availability lead to increased energy levels and allowed the heart muscle to relax in between beats, fill fully with blood and pump more efficiently. Also, increased tolerance to exercise, decreased oxygen used by the heart, increased endurance and increased quality of life resulted in more than 66% of the tested subjects.

Various other D-ribose reviews show similar results concerning enhancements of heart muscle performance. D-ribose supplementation is known to free of serious or long-lasting side effects. Headaches, nausea, diarrhea and other mild side effects may result.

There are also some prescription drugs which contraindicate with D-ribose. Please talk with a doctor before starting D-ribose supplementation.

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