DAA Pure Supplement Review, Effects and Results

DAA Pure is the name of a D-aspartic acid (DAA) supplement sold by Performance Edge.

DAA Pure is promoted as “an innovative breakthrough in cutting-edge performance nutrition” and is targeted to bodybuilder and athletes who want to improve muscle growth and promote athletic performance.

DAA supplements are often used to increase testosterone levels in men. DAA is a non-essential amino acid naturally produced by the body. DAA has been associated with the biochemical pathway that leads to the production of testosterone.

Individuals often supplement with D-Aspartic Acid to increase testosterone production. However, preliminary research results indicates that DAA does not increase testosterone levels in already healthy and active males.

It may cause short-term increases in free testosterone for athletes, but the majority of benefits are observed in individuals with already low testosterone levels. However, DAA Pure and other supplements with this ingredient continue to be used by men for sexual health and increased muscle mass and strength.

D-Aspartic Acid

Amino Acid

Testo -sterone

Libido

Athletics

How It Works:

• Shown to increase testosterone production
• Supports athletic performance, fat loss & strength
• Boosts sexual health & libido

Dosage:

Between 4 - 8 g per day

Safety:

Generally Well Tolerated

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DAA Pure Supplements

DAA Pure provides 750 mg of D-Aspartic Acid per capsule, with a recommended dosage of 4 capsules.

This is equivalent to a recommended daily dosage of 3 grams. This is the dosage that is most often used in research trials on DAA.

According to the manufacturers, this supplement is involved in increasing cyclic AMP (cAMP) levels in the brain. It is involved in the neuroendocrine axis, which includes the hypothalamus and pituitary gland.

DAA enhances the release of GnRH, which is a hormone used by the body to regulate testosterone levels. When levels of GnRH are low, the body synthesizes and releases more testosterone. DAA is also reportedly involved in the production of the hormones oxytocin and vasopressin.

Uses of DAA Supplements

Most of the scientific information on D-Aspartic Acid and supplements like DAA Pure comes from investigation into its natural actions in the body. The amino acid was only released as a supplement in the mid-1990s.

Although most of the research into DAA does not speak to the effects of supplementation, some studies have specifically investigated the effect of taking oral DAA capsules or powder.

Despite the lack of clear scientific evidence, DAA supplementation is growing in popularity and is often used in the hopes of increasing testosterone levels to improve sexual and athletic performance.

Adherents also believe that because DAA is produced ‘naturally’ that it is safe and largely without side effects. In the available studies, but there is insufficient evidence to understand the effects of long-term supplementation.

Additionally, the lack of clinical data on DAA supplementation means there are no precise dosing standards available. Doses between two and three grams per day have been associated with increased testosterone and improved fertility profiles in particular groups of men.

Boosting Testosterone with DAA Pure

The popularity of testosterone replacement therapy (TRT) has grown in recent years. Men produce less testosterone as they age and low testosterone levels can lead to a variety of negative symptoms, including fatigue, low libido and decreases in muscle mass.

The consequences of low testosterone have led many men to seek ways to increase testosterone in the body, and one of the most common ways is to undergo TRT.

However, the increase in TRT treatments has led to growing concern by regulators about the cardiovascular risks associated with the treatment. This has some looking for alternative, “natural” testosterone options, which brings many to DAA.

DAA does not directly produce testosterone. Instead, it is an integral component of a cascade or pathway that eventually leads to testosterone production. Because it is not a direct precursor to testosterone, the connection between DAA and the hormone is less direct than commonly claimed.

Effects of D-Aspartic Acid in the Body

DAA plays an important role in testosterone production by encouraging the synthesis of a number of compounds that play an active role in testosterone synthesis.

First, it increases synthesis of StAR (steroidogenic acute regulatory protein) mRNA.

StAR is a transport protein that modulates the transfer of cholesterol into the mitochondria – or energy center – of the cell. StAR is also known to regulate Leydig cell activity – the cells contained in the testes that produce testosterone.

DAA supplementation may help trigger an increase in the amount of N-methyl- D-aspartic acid (NMDA) present in the anterior pituitary gland. When a sufficient accumulation is detected, growth hormone release hormone (GHRH), prolactin release factors (PRF) and gonadotropin release hormone (GnRH) production rates are increased.

Subsequently, human growth hormone (hGH), follicle stimulating hormone (FSH) and luteinizing hormone (LH) synthesis are all increased. LH and FSH then travel via the hypothalamic-pituitary-testicular pathway and arrive in the testicles. Inside the testicles, the Leydig cells use LH and FSH to synthesize testosterone.

Clinical studies on DAA supplementation have indicated that free serum testosterone levels are increased with routine supplementation. In one study, a 42 percent increase in testosterone was observed after 12 days of supplementation (daily dose was 2.66 grams).

In healthy, athletic participants, testosterone levels were observed to quickly return to baseline levels. In studies of non-athletic men with infertility issues, the testosterone increases were observed to last much longer after discontinuing supplementation.

Additional Benefits of DAA Pure

DAA Pure and other Da-Aspartic Acid supplements may have a positive effect on memory and cognitive function. This is an area that requires further research to understand the implications.

In one animal (rat) study, sodium-DAA was administered for 12 days. Overall neuronal function and memory were improved, based on results from Morris Maze testing. Rats that received no DAA took between 20 and 30 seconds to find a hidden platform. Rats in the treatment group found the platform in five seconds (plus or minus two seconds).

The dosage in this study was based on roughly 0.19 milligrams of sodium-DAA per one kilogram of bodyweight. No negative side effects were noted.

There is some evidence that DAA is effective in improving the symptoms of male infertility. In one study, men with infertility exhibited a 26 percent conception rate within 90 days of DAA supplementation. These men and their partners were unable to conceive prior to the study.

Clinical study of DAA supplementation indicates general improvements in spermatogenesis. Sperm motility was observed to increase between 50 and 100 percent in men with infertility. Also, sperm count increased between 50 and 100 percent over baseline levels.

The quality of sperm also seemed to improve significantly, but additional tests with a proper comparison or placebo group are required to substantiate these findings.

DAA Pure Review

DAA Pure supplements may be effective for increasing testosterone in infertile men or sedentary men. In athletes, it is only associated with a modest short-term increase in testosterone levels.

The long-term effects of DAA supplementation remain ill-defined. Be sure to speak with your doctor before supplementing with DAA Pure or any other supplement to make sure it is safe for you to use.

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