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Draganon is one of the brand names for Aniracetam, a nootropic drug developed by the Hoffman-La Roche company in the 1970’s.
It is dually classified as a Racetam and an Ampakine, supporting stimulation of both acetylcholine and glutamate neural receptors.
Draganon has been used clinically to treat neuropsychological deficits in patients with dementia and Alzheimer’s disease, progressive cognitive decline, depressive personality, and brain function deterioration linked to cerebrovascular disease and stroke.
Draganon is also used off-label as a nootropic supplement or smart drug. It has been observed in research studies to facilitate learning, focus, social behavior and increased memory capacity.
This cognitive enhancer is also taken as a mood booster and concentration aid, purported to promote mental energy, feelings of relaxation and higher levels of motivation.
In this Draganon review, we will look at some of the benefits of this Nootropic, how it works, the risk of side effects as well as tell you where you can buy it online. Buy Aniracetam online at this link.
Motivation
Memory
Mood- Heightens focus & motivation
- Supports memory formation & recall
- Shown to enhance mood & reduce anxiety
What is Draganon
Related Topics
- What is Aniracetam?
- User Reviews
- Effects and Benefits
- Aniracetam for Anxiety
- Dosage Suggestions
- Using Aniracetam Powder
- Best Way to Take
- Side Effects
- Aniracetam for Sale
- Buyer's Guide
- Is Aniracetam Legal?
- Stacking with Piracetam
- Stacking with Choline
- Comparison to Piracetam
- Comparison to Oxiracetam
- Comparison to Pramiracetam
- Comparison to Noopept
Draganon is a fat soluble compound that has a Racetamic chemical structure with a 2-pyrrolidinone nucleus.
It is a derivative of Piracetam, which was the first nootropic drug ever identified. It has a chemical structure of N-anisoyl-2-pyrrolidinone.
Due to the modifications in its molecular structure, it is considered to be five times more potent than its cousin Piracetam.
It has better bioavailability and crosses the blood-brain barrier much faster than its predecessor.
Key purported benefits of Draganon include: the formation of new connections between neurons (synapses); increasing the plasticity of the brain; and preventing damage in brain cells caused by aging and other environmental factors.
Draganon is also sold under other names including generic Aniracetam, Ampamet, Conectol, Referan and Memodrin.
This drug is approved in Europe where it is used to treat the cognitive and behavioral symptoms associated with Senile dementia of Alzheimer’s type (SDAT).
Research Review
Draganon (Aniracetam) has been studied for its effects on patients with Alzheimer’s disease as well as in elderly persons showing signs of Age-Related Cognitive Decline.
In one study, Aniracetam was found to improve mental performance in elderly individuals diagnosed with mild to moderate cognitive impairment.
Dosages of 1500 mg per day of this nootropic drug were given for four or six months and were found to be more effective than a placebo for improving cognitive function.
Over the 6-month trial, study participants were examined across a battery of 18 tests designed to measure their brain function, memory, reasoning and ability to manipulate data.
At the conclusion of the trial, those given daily dosages of Aniracetam saw the greatest improvement in their performance and showed gains on 17 of the 18 tests administered.
This study found that Aniracetam was more effective than a 2400 mg per day dosage of Piracetam in 8 of the 18 tests administered. Results also showed that Aniracetam was well-tolerated with no serious side effects and no increase in hepatic liver enzyme levels. [1]
In a recent study published in 2011, use of generic Aniracetam was studied in patients with cognitive impairment, compared to those given a cholinesterase inhibitor (ChEI) drug.
Cholinesterase inhibitors – like Galantamine (Reminyl ER) or Huperzine A – are often used in the treatment of Alzheimer’s disease and other conditions affecting memory function.
They work by preventing the breakdown of the acetylcholine neurotransmitter once it has been released from a neuron. This results in increased activation of cholinergic receptors which are involved in memory and general cognition.
In this prospective, open label study, 276 patients diagnosed with cognitive disorders with a mean age of 71 years were enrolled. Patients were given either a placebo, aniracetam therapy on its own, cholinesterase inhibitor therapy on its own, or a combination of Aniracetam and ChEIs.
Patients were given validated neuropsychological tests at the start of the trial, and after three, six and twelve months of treatment.
The results of this study showed that the group given Aniracetam exhibited significantly better mental performance after 6 months of therapy and improve functionality after 3 months. This group also experienced improved measures of emotional state.
The researchers stated that Aniracetam preserved results across all neuropsychological parameters for the 12 months during the study treatment period and exerted a beneficial effect on mood.
They concluded, “Aniracetam (a nootropic compound with glutamatergic activity and neuroprotective potential) is a promising option for patients with cognitive deficit of mild severity.”
While Draganon is still used in some European countries to address dementia, Parkinson’s disease and Alzheimer’s disease, it has not been approved as a therapeutic agent in the United States.
More research is needed to understand the potential nootropic effects of this compound on healthy adults not suffering from some form of cognitive impairment.
Draganon Effects and Benefits
If you have not been diagnosed with dementia or cognitive decline, what are the purported benefits of taking Draganon 750mg tablets?
This has not been well-researched in clinical studies and most of the information we have available on its purported benefits come from user reviews.
When taking Draganon, individuals have reported that they find it easier to remember small details and learn new information.
Draganon increases the sensitivity of acetylcholine synaptic receptors in the hippocampus related to the formation of new memories. It also enhances glutamate receptor activity in the cerebral cortex.
AMPA glutamate receptors mediate fast synaptic transmission in the Central Nervous System. They are also involved in neuroplasticity and synaptic transmission, as well as long-term potentiation.
Long-term potentiation (LTP) is considered to be the primary cellular mechanisms that facilitates learning and memory. To the extent that Aniracetam can promote LTP, it may improve memory formation.
For many users, the typical Draganon experience consist of not having to work as hard when studying or learning new skills on the job. You may also find that you have been access to previously learned information and get more use out of it in your daily activities.
For example, you may be able to recall very specific facts during conversations with clients or with your boss and you may find that your general speed of cognition increases.
Draganon also has positive implications for psychological energy levels and mood. Not only does this nootropic agent reduce anxiety – particularly shyness or social anxiety – it can also lessen the negative feelings that come with depression.
It has been used in the treatment of post-operative anxiety and depression for individuals who have experienced a cerebral ischemia (stroke). It exerts a notable anxiolytic effect in many users, which means it calms them down and helps prevent over-stimulation.
Draganon powder is associated with greater release of serotonin and dopamine which are two of the neurotransmitters involved in positive emotions. They are also part of the reward or pleasure system of the brain which may be connected with the experience of greater ambition and confidence when taking Dragaon.
Connected with these benefits is an increased degree of concentration so that you can focus more intently on reaching your goals.
- Improves memory and learning
- Heightens focus and motivation
- Enhances mood and reduces anxiety & stress
How Racetam Nootropics Work
If you are not familiar with how nootropics work, a short introduction to neuroscience is a good place to start.
Inside your brain, you have an estimated 86 billion neurons. These neurons communicate with each other and form neural networks via synapses which are the physical connections between neurons.
A single neuron may be connected to over 10,000 others by way of a complex map of neurites.
At the synapses of these neurons, one side will store and possess neurotransmitters and the other side will posses a number of receptors that are typically sensitive to only one type of neurotransmitter.
By releasing neurotransmitters, your neurons are therefore able to communicate with each other. Two of the most important excitatory neurotransmitters in the brain are glutamate and acetylcholine.
The receptors for these neurotransmitters are intimately involved with functions related to learning and memory. Acetylcholine receptors are believed to be involved in short-term memory, attention and focus. Glutamate receptors play a role in long-term memory formation and recall.
They are specifically involved in the idea of neuroplasticity which takes into account how adaptable your brain is and how easily it is able to form new connections between neurons.
By boosting the activity of these neurotransmitters, you can actually cause memories to be formed and recalled more easily and improve the speed of cognition and reasoning. This is the principle upon which Draganon and other nootropics work.
Racetams are observed to pass through the blood-brain barrier and facilitate or amplify the signals sent and received by cholinergic and glutamatergic neurons. They also potentiate other forms of neurotransmission in the brain.
By turning up the volume on these signals, the result is generally enhanced cognitive function, especially in individuals who have been diagnosed with some form of impairment.
While this is an oversimplification of how the nootropic effects of Aniracetam work, the fundamental idea that these compounds facilitate greater neuronal communication is accurate.
More research is needed to understand how this compound affects short and long-term memory in healthy individuals. While students claim that it helps them to study better, this has never been examined in a double-blind placebo controlled research trial.
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Draganon Dosage
You will typically see Draganon sold in 750 mg tablets, but most user reviews suggest taking at least twice this amount for full effects.
The dosage range typically taken is 750 mg to 3000mg, split into three doses per day to combat the short half-life of this compound.
It is recommend that you use Draganon on a full stomach or after eating foods with fatty acids. These fatty acids are necessary for Draganon to be absorbed from your gut so that it can reach your brain.
Some people also recommend cycling Draganon to prevent your receptors from developing a tolerance to the effects of this nootropic drug.
It is generally used with a choline source like Alpha GPC choline supplements or Phosphatidylcholine. Some people say that this combination improves the efficacy of this nootropic supplement and reduces the occurrence of headaches.
However, others experience more side effects when taking Aniracetam powder with choline sources. Alpha GPC, CDP Choline, Centrophenoxine, DMAE and other supplements have their own adverse effects that need to be considered as well.
Buy Draganon
It is difficult to find brand-name Draganon tablets or granule sachets online. Instead, you should look for generic Aniracetam which is the active chemical component of Draganon.
Aniracetam is sold in either tablet form or in powdered form with the latter being a much cheaper option. As of 2014, Aniracetam is legal in the United States without a prescription and in most other countries around the world.
You can currently buy bulk Aniracetam powder or purchase it in capsule form. This is one of the most affordable nootropic agents available in comparison to Pramiracetam, Phenylpiracetam or even Noopept.
Side Effects Reported
In research trials, this nootropic has demonstrated a good safety record and it is typically well tolerated by study participants.
The class of racetams as a whole are believed to be safe with no toxic effects and no serious side effects reported.
Some people have reported negative reactions to the drug. These are generally mild and pass quickly when you discontinue use.
Some of the side effects reported include headaches, nausea, dizziness, increased sweating, appetite suppression, skin rash, confusion, irritability, agitation and excessive movement (jitters).
Before you decide to buy Draganon pills online, consult with a doctor to determine whether this product is appropriate for you or whether it may interact with any other drugs or supplements you are using.
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- Lee CR, Benfield P. Aniracetam. An overview of its pharmacodynamic and pharmacokinetic properties, and a review of its therapeutic potential in senile cognitive disorders. Drugs Aging. 1994 Mar;4(3):257-73.
- Yamada K, Inoue T, Tanaka M, Furukawa T. Prolongation of latencies for passive avoidance responses in rats treated with aniracetam or piracetam. Pharmacol Biochem Behav. 1985
- Elston TW, Pandian A, Smith GD, Holley AJ, Gao N, Lugo JN. Aniracetam does not alter cognitive and affective behavior in adult C57BL/6J mice. PLoS One. 2014
- Toide K. Effects of aniracetam on one-trial passive avoidance tests and cholinergic neurons in discrete brain regions of rats. Arch Int Pharmacodyn Ther. 1989
- Cumin R, Bandle EF, Gamzu E, Haefely WE. Effects of the novel compound aniracetam (Ro 13-5057) upon impaired learning and memory in rodents. Psychopharmacology (Berl). 1982
- Wijayawardhane N, Shonesy BC, Vaglenova J, Vaithianathan T, Carpenter M, Breese CR, Dityatev A, Suppiramaniam V. Postnatal aniracetam treatment improves prenatal ethanol induced attenuation of AMPA receptor-mediated synaptic transmission. Neurobiol Dis. 2007
- Fallarino F, Genazzani AA, Silla S, L'Episcopo MR, Camici O, Corazzi L, Nicoletti F, Fioretti MC. [3H]aniracetam binds to specific recognition sites in brain membranes. J Neurochem. 1995
- Himori N, Mishima K. Amelioration by aniracetam of abnormalities as revealed in choice reaction performance and shuttle behavior. Pharmacol Biochem Behav. 1994
- Kimura M, Okano S, Inoué S. Effects of aniracetam on impaired sleep patterns in stroke-prone spontaneously hypertensive rats. Psychiatry Clin Neurosci. 2000
Article last updated on: March 13th, 2018 by Nootriment