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What Galantamine dosage should you be using in order to achieve the best results with this memory-boosting supplement?
Galantamine is also marketed under a number of different brand names including Nivalin, Razadyne, Reminyl (ER), and Lycoremine.
As a supplement it is current being used in the treatment of Alzheimer’s disease and other memory impairments, particularly those having a vascular origin.
This supplement is an alkaloid that may be obtained synthetically or from the bulbs and flowers of several different types of plants, such as Galanthus caucasicus (Caucasian snowdrop) and related genera.
The use of this supplement first began in the Soviet Union back in the 1950’s. They discovered that it had a significant effect upon a key brain chemical and neurotransmitter system.
Since then, it has been used throughout Russia and Eastern Europe to treat conditions like myasthenia, myopathy, and sensory or motor dysfunctional conditions.
It is also well-known for its Nootropic properties, leading to improved brainpower and focus. In the United States, it is currently one of the drugs that has been approved for use in the treatment of mild to moderate cases of Alzheimer’s disease.
Memory
Mental Function
Neuro- protective- Inhibits acetylcholinesterase enzyme in the brain
- Improves memory & mental performance
- Boosts concentration & brain cell health
Effects of taking a Galantamine Dosage
Related Topics
Within the United States, the main clinical use of this supplement is for the treatment of Alzheimer’s disease.
This is most often used as an adjunct treatment, since it can only lessen the severity of symptoms and cannot cure or reverse the disease.
However, it is known to help slow down the progression of the disease and it produces improved cognitive function in patients.
Many healthy people have begun turning to Galantamine capsules for their reported Nootropic benefits. This supplement can improve memory formation and recall, enhance learning capacity, increase attention span and even improve mood. Galantamine may be used on its own or combined with choline supplements for increased effects.
Top Galantamine Supplements
Additional benefits of this supplement relate to how it may improve or influence sleep patterns. Taking a Galantamine dose later in the day is proven to help an individual in falling asleep more quickly and improving sleep quality.
Galantamine has also been found to increase dreaming activity which can have a positive effect on memory retention. Other people use this supplement to promote a state of lucid dreaming. In this state, a person will be aware that they are dream and have the ability to control the dream while they are experiencing it.
Sometimes, this situation can also lead to an out-of-body experience and it is effective for positive visualization techniques.
How Does Galantamine Influence the Brain?
The primary effect of Galantamine in the brain is to increase levels of the acetylcholine neurotransmitter. It does this by inhibiting the effects of a specific enzyme called acetylcholinesterase (AchE).
When this enzyme is inhibited, or prevented from working as it normally does, this causes levels of Acetylcholine in the brain to rise, since the enzyme is normally responsible for the breakdown of this key brain chemical.
When the levels of Acetylcholine in the brain are increased, this can enhance brain function in several different areas. This vital chemical partakes in a number of cognitive processes like memory formation, the ability to sustain attention, and our ability to think and learn.
In this respect, Galantamine is very similar to supplements like Huperzine A which is also an acetylcholinesterase inhibitor.
- Inhibits acetylcholinesterase enzyme
- Increases acetylcholine levels to support memory
- Enhances mental clarity and attention span
Galantamine Dosage
Galantamine is a very powerful supplement and you only need a very small effective dosage in order to see results. Most Galantamine hydrobromide supplements come in either 4mg or 8mg denominations and generally it is the lesser of the two that is used for nootropic purposes. A dosage of one to two capsules may be taken up to two or three times a day.
In clinical trials for Alzheimer’s patients, the most effective Galantamine dosage was between 16-32 mg per day. Our recommendation is to begin with a 4 mg dosage once a day to determine your own lowest effective dosage level. Only increase from this amount after you have safely used it for several days without any side effects present.
If you are planning to use Galantamine as a lucid dreaming aid, it is common to take 4 to 8 mg after 5 to 6 hours of deep sleep. You should then fall back to sleep and your acetylcholine levels will be highest during the period of the night when dreaming activity is highest and most likely to produce a lucid state.
Is Galantamine Safe?
In the vast majority of cases, taking a recommended Galantamine dosage is safe and well-tolerated in healthy results. There have been a few rare allergic reactions, so be very careful, especially if you are allergic to daffodils.
Other side effects can include loss of appetite, nausea, tiredness, dizziness, and headaches. Do not take this with other acetylcholinesterase inhibitors like Huperzine A, however you can safely stack Galantamine with other cholinergic supplements like Alpha GPC or Citicoline for added benefits.
- Li Q, Wu D, Zhang L, Zhang Y. Effects of galantamine on β-amyloid release and beta-site cleaving enzyme 1 expression in differentiated human neuroblastoma SH-SY5Y cells. Exp Gerontol. 2010
- Ago Y, Koda K, Takuma K, Matsuda T. Pharmacological aspects of the acetylcholinesterase inhibitor galantamine. J Pharmacol Sci. 2011
- Caramelli P, Laks J, Palmini AL, Nitrini R, Chaves ML, Forlenza OV, Vale Fde A, Barbosa MT, Bottino CM, Machado JC, Charchat-Fichman H, Lawson FL. Effects of galantamine and galantamine combined with nimodipine on cognitive speed and quality of life in mixed dementia: a 24-week, randomized, placebo-controlled exploratory trial (the REMIX study). Arq Neuropsiquiatr. 2014
- Freund-Levi Y, Jedenius E, Tysen-Bäckström AC, Lärksäter M, Wahlund LO, Eriksdotter M. Galantamine versus risperidone treatment of neuropsychiatric symptoms in patients with probable dementia: an open randomized trial. Am J Geriatr Psychiatry. 2014
- Ghaemi SN, Gilmer WS, Dunn RT, Hanlon RE, Kemp DE, Bauer AD, Chriki L, Filkowski MM, Harvey PD. A double-blind, placebo-controlled pilot study of galantamine to improve cognitive dysfunction in minimally symptomatic bipolar disorder. J Clin Psychopharmacol. 2009
- Elgamal SA, Marriott M, Macqueen GM. Electroencephalographic effects of galantamine in major depressive disorder. J Clin Neurophysiol. 2009
- Dev H, Agius M, Zaman R. The dramatic effects of Galantamine in a patient with early-onset Alzheimer’s disease. Psychiatr Danub. 2010
