Galantamine is a nootropic from the acetylcholinesterase inhibitor class of substances.
This natural plant extract has been found to increase levels of the acetylcholine neurotransmitter in the brain by preventing its breakdown, similarly to Huperzine A.
The benefits of this herbal supplement can include improved memory, focus and alertness.
In some countries, Galantamine is sold as a prescription drug under the name Reminyl ER to treat Alzheimer’s, Dementia and other forms of cognitive impairment. In the USA, this ingredient can be purchased without a prescription as a dietary supplement.
It is commonly taken in nootropic stacks along with a choline source, or used recreationally to promote lucid dreaming. What is the typical experience when using Galantamine?
The following is a guest post review from Stephen of SmartDrugsForCollege regarding his experiences with Galantamine supplements.
Disclaimer: Information contained in this review is the opinion of the respective author and are not the views of Nootriment.com. The website SmartDrugsForCollege is a retailer of Galantamine supplements.



- Inhibits acetylcholinesterase enzyme in the brain
- Improves memory & mental performance
- Boosts concentration & brain cell health
Galantamine User Review
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“Galantamine, a hugely popular nootropic drug with significant benefits on focus, memory, mood and energy levels, has been widely raved about for its abilities to invoke lucid dreaming, and vivid dreaming, in its users-something I can firmly attest to from my own personal experiences with taking the smart drug.
“Used for centuries as a Chinese herbal medicine that can take one to the deepest realms of the subconscious mind, I had to give this amazing nootropic drug a shot, and see just how vivid and powerful a dream, under the influence of a powerful nootropic, could truly be.
“This blog post will outline exactly what you’ll feel and what to expect if you take a Galantamine, leaving the science of what exactly it does to the brain alone, in favor of a layman’s perspective of your experience in lucid dreaming under the nootropic influence.
“The first time I took a galantamine, within an hour of it hitting me I noticed better fluidity of sentences, clarity of thought, an improved sense of vision and special awareness, and overall felt like I was in a much more crisp, clear, euphoric state of being. It wasn’t like taking an Adderall or even a Modafinil where you get an energy rush and feel jittery, instead I felt just like myself, only with better focus and memory.
“My brain felt “turned on” and “cleaned out” in a sense of the word. What I really looked towards galantamine for however, was in the way of its improved perspective on dreaming.
“Reports online and in medical journals stated that it improved ones dreaming much the same way a high dosage of nicotine does, by making you moderately tired, and letting you get into deeper patterns of REM sleep. In this area especially, it paid off with great results.
“The dreams were so vivid and lucid that I could control most aspects of the dream, and that it felt entirely real. It can get a little scary at times if you get up to the higher dosages of galantamine (16-24mg and higher) so staying with 8mg before you’re experienced with the nootropic is a must (standard one capsule dosage from all nootropics retailers.)
Review of Side Effects
“Galantamine has very little noticeable side effects, and the only thing you may run across when taking this nootropic regularly is a slight headache (it uses choline for its main mechanism of action..among other neurotransmitters unique to most nootropics), take a CDP Choline and any side effects from this phenomenon will quickly subside.
Cognitive Benefits
“When taking Galantamine you’ll notice much improved clarity of thought, more energy and mental endurance, and when exercising, greater stamina. Galantamine is great for long term use also, it displays cumulative effects, and when taken for up to six weeks on a continuous basis.
“Galantamine is a great nootropic supplement for anyone needing to perform rigorous mental activities, or wanting to explore the limits of what dreaming can truly do.”
- Tsvetkova D, Obreshkova D, Zheleva-Dimitrova D, Saso L. Antioxidant activity of galantamine and some of its derivatives. Curr Med Chem. 2013
- Kavanagh S, Van Baelen B, Schäuble B. Long-term effects of galantamine on cognitive function in Alzheimer's disease: a large-scale international retrospective study. J Alzheimers Dis. 2011
- Penner J, Rupsingh R, Smith M, Wells JL, Borrie MJ, Bartha R. Increased glutamate in the hippocampus after galantamine treatment for Alzheimer disease. Prog Neuropsychopharmacol Biol Psychiatry. 2010
- Walsh R, Rockwood K, Martin E, Darvesh S. Synergistic inhibition of butyrylcholinesterase by galantamine and citalopram. Biochim Biophys Acta. 2011
- Guo S, Hernandez L, Wasiak R, Gaudig M. Modelling the clinical and economic implications of galantamine in the treatment of mild-to-moderate Alzheimer's disease in Germany. J Med Econ. 2010
- Li Q, Fang J, Yang M, Wu D, Zhang L, Zhang Y. Galantamine inhibits calpain-calcineurin signaling activated by beta-amyloid in human neuroblastoma SH-SY5Y cells. Neurosci Lett. 2010
- Li Q, Wu D, Zhang L, Zhang Y. Effects of galantamine on β-amyloid release and beta-site cleaving enzyme 1 expression in differentiated human neuroblastoma SH-SY5Y cells. Exp Gerontol. 2010
Article last updated on: May 10th, 2018 by Nootriment