GPC Choline is a supplement that is used for improving memory recall, critical analysis skills, reaction time, and mood.
Some research has even been done on using GPC Choline for Alzheimer’s disease, dementia, or even suffering age-related cognitive decline.
The safe and well-tolerated GPC Choline supplement is a naturally enhanced version of the essential nutrient Choline. GPC Choline has a number of different Nootropic benefits aimed at improving cognitive function, boosting neuron health, and counteracting the development of mental impairments in the future.
GPC Choline is also known as Choline Alfoscerate or Alpha GPC Choline, which stands for L-Alpha glycerylphosphorylcholine. What is GPC Choline and can it help with brain functioning?



- Choline source to support memory function
- Increases attention, focus & energy
- Neuroprotective for brain cell health
What Is Choline?
Related Topics
- Alpha Glycerylphosphorylcholine
- What is Choline?
- Alpha GPC Choline Content
- Health Benefits
- Dosages to Take
- User Reviews
- Side Effects
- Uses for Memory
- Effects on the Brain
- Increasing Growth Hormone
- Using Alpha GPC Powder
- Where to Buy Online
- Best Supplement Sources
- Comparison to CDP Choline
- Choline Alfoscerate
- Stacking with Piracetam
Choline is an essential vitamin-like nutrient that is similar to the B vitamin family. It is a water soluble compound and a phospholipid found within the cell membranes of our neurons.
This nutrient is necessary for cognitive abilities like memory, learning, logical reasoning, creative thought and problem solving. It also has an important role in preserving whole-body health by preventing the accumulation of fat deposits in the liver.
It is produced by the liver, by not in sufficient quantities to satisfy our normal daily requirements.
There are a number of food sources for Choline like eggs, liver, fish, beans, and wheat germ. However, most of us do not get enough Choline to support maximal brain potential with as many as 9 out of every 10 adults considered to be deficient in this nutrient.
GPC – A Better Choline Source
While some people will use Choline Bitartrate supplements to help them boost their brainpower and improve their memory, neuroscientists have discovered another natural form of Choline that is much more effective at influencing changes in your brain.
GPC Choline is the best version of this nutrient because it is better at crossing the blood-brain barrier and delivering Choline directly to the central nervous system.
This has to do with the fact that Alpha GPC is a good source of phospholipids while Bitartrate is a salt and not a lipid compound. As such, Choline Bitartrate has to combine with a fatty acid into the brain while GPC Choline already has this included.
Once the Alpha GPC Choline reaches your brain, it is used to build new neurons, cell membranes, and also leads to the synthesis of Acetylcholine.
Of all of the different types of Choline supplements available, GPC Choline has the highest conversion into the Acetylcholine neurotransmitter in your neurons.
If you know anything about cognitive enhancers and nootropics, you will know that raising levels of Acetylcholine can go a long way to improving your memory, mental flexibility, and information processing.
This neurotransmitter is involved in many of the basic brain communication that creates our stream of conscious perceptions and thoughts. GPC Choline is often used with more powerful nootropics such as Piracetam or Aniracetam because it supports their mechanisms of action.
It has even been known to help fight certain side effects commonly associated with Racetams like headaches.
GPC Choline & Brain Functioning
There are several actions within the brain that GPC Choline participates in which make it an essential component of brain functioning.
First, it fuels tissue renewal and builds Acetylcholine. In fact, Choline is so vital to nerve functioning that without this nutrient we would not be able to move, think, or remember anything.
GPC Choline also is used to synthesize a chemical called phosphatidylcholine. This is a component of every cell membrane and it also acts as a Choline reserve for building more Acetylcholine whenever it is needed.
How GPC Choline Works
GPC Choline has a slightly different method of action than other Choline sources.
First off, because of its highly bioavailable formula, it becomes active in your nervous system much faster with effects being seen in as little as 20 minutes.
GPC Choline is a direct precursor to Acetylcholine with this compound naturally breaking down into this neurotransmitter and being stored in your neurons.
It results in greater choline uptake than any other source of Choline or acetylcholine supplement.
At this point, it also contributes to the phosphatidylcholine reserves in your cells and worn out cell membranes in the neurons are repaired and made more fluid. This ensures that your neurons are able to communicate efficiently and may have the effect of making your thoughts seem faster.
GPC Choline Dosage & Usage
The following dosage recommendations are general guidelines only, and your personal dosage may be different. Proper dosage is dependent on many different factors including age, personal sensitivities, and physiology. It is recommended that you speak with your doctor before beginning any new supplements to help determine the best dosage for your needs.
As far as the recommended usage is concerned, it is important to remember that this supplement can be a bit stimulating. Many users report feeling more alert, energized and better able to concentrate after taking a GPC Choline dosage.
Therefore, many people begin at the lower end of the 400 to 1200 mg suggested daily range. Also, try to avoid taking it after dinnertime as it may make it difficult for you to sleep when dosed late in the day.
Choline supplements are often well tolerated and considered safe, and can have a powerful range of benefits for your brain. You can look for GPC Choline for sale on its own or buy a stack supplement product like Alpha Brain which includes Alpha GPC Choline in its ingredients.
While research on GPC Choline for neurological improvements has been very promising so far, more research is still needed, especially large-scale human trials. At this time, GPC Choline is available as a health supplement only, and the FDA has not approved Choline as a drug to prevent or treat any conditions.
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Article last updated on: March 13th, 2018 by Nootriment
1 Comment
Hello,
I have started taking alpha GPC 1200 mg to offset the effect of some damage to my natural memory over last 22 years’ stressful life. Can you please tell me how long I should take it to reverse the damage?
Thanks