Idebenone powder is an anti-oxidant brain supplement that shows benefits for memory, treating cognitive impairments, heart disease, nerve conditions and slowing signs of aging.
Not only can it boost brain health and mental function it can also prevent wrinkles and oxidative damage throughout the body.
If you are familiar with the supplement Co-Enzyme Q10, it will help your understanding to think of Idebenone as a synthetic analog of this compound.
Idebenone powder is viewed as much more effective than CoQ10 because it does not break down as quickly n the body. This difference comes from the fact that it is a shorter chain quinone which makes it more available and active within the body.



- Potent anti-oxidant for anti-aging benefits
- Supports ATP production & enegry levels
- Promotes cognitive function & memory
Why Use Idebenone Powder?
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Not unlike CoQ10, Idebenone works like an anti-oxidant.
It eliminates free radicals within the brain and throughout the body, helping to prevent oxidative damage from occurring in cells.
This can promote better functioning in a number of different organs including the brain, heart and skin by reducing the potential for damage. A regular supplementation program with Idebenone may even be instrumental in lowering the risk of cancer.
Additionally, this supplement increases something known as nerve growth factor (NGF) in brain tissue. This protein is involved in the development, growth and protection of neurons and nerve cells within the brain.
Researchers think that higher levels of NGF can lead to the formation of new neurons and synapses, leading to a more plastic and adaptable brain. If brain cells are better able to form new connections, this can lead to wide ranging improvements in overall brain function.
Specifically, Idebenone powder may be able to positively affect memory performance as well as acuity and intelligence scores.
Anti-Aging Effects of Idebenone
In addition to the protective qualities it exhibits as an anti-oxidant, Idebenone can also slow down signs of aging and promote life extension benefits. It does this by targeting sources of potential damage within your cellular mitochondria.
These are the components of our cells throughout the body that are responsible for generating energy. As we age, mitochondrial reserves tend to become depleted.
Idebenone is able to zero in on these mitochondria cells within the brain, heart, and skeletal muscles and quench free radicals that would otherwise impair cell function over time. Free radicals are high-energy oxygen particles that have lost one electron.
In this state, these oxygen particles are capable of causing serious damage to cell structures as well as premature cell aging and death. Idebenone capsules work even under conditions of low oxygen levels to reverse this damage and helps to keep energy production high.
Furthermore, Idebenone acts as an organ protector when oxygen levels are insufficient. As we age, the blood flow to our organs is diminished. This reduces the amount of available oxygen circulating to our cells. The result is a decline in cellular energy production which is necessary to conduct normal functions but also repair and maintain organ structure.
If this is allowed to continue, a crucial threshold is reached where too many cells within the organ are damaged. At this point, organ function will be significant impaired or the organ may fail entirely. According to research studies, Idebenone is capable of protecting our organs from low oxygen and poor blood flow, maintaining proper organ energy production and good overall function.
Mental Benefits of Idebenone
Taking Idebenone powder can also support healthier levels of neurochemicals in the brain. This supplement will enhance serotonin production, even if you are eating a very low tryptophan diet (which is the precursor to serotonin).
Tryptophan deficiency is often pointed to as a potential cause for anxiety and high stress levels. Idebenone may be able to reduce anxiety symptoms by restoring serotonin levels so that a positive, calm state of mind can be preserved.
Idebenone also increases the production of Dopamine, Adrenaline, and Noradrenaline by enhancing the cellular uptake of the amino acid tyrosine. L-tyrosine is the precursor for these catecholamine neuro-hormones which play a major role in regulating your mood, energy and focus.
When you stabilize levels of dopamine, adrenaline and noradrenaline, it leads to increased memory performance, longer attention span, greater concentration and drive as well as proper glucose utilization and ATP energy production in the brain.
Idebenone vs. CoQ10 Powder:
If you are deciding between Idebenone supplements and CoQ10, you may be wondering whether the advantages warrant spending more to buy Idebenone rather than the readily available Co-enzyme Q10.
In our opinion, the increased potency more than justifies any additional cost. As an anti-oxidant, some studies have shown Idebenone to be as much as 100 times more effective.
It is also better than Coq10 at lessening the free radical induced damage to the mitochondrial DNA. It is this damage, more than anything else that is thought to accelerate the negative effects of aging upon the body.
Studies have also shown that Idebenone is more effective at preserving liver tissue under conditions needed for transplantation. Furthermore, Idebenone promises cognitive benefits that are not visible when taking CoQ10 pills.
It is well-established that CoQ10 cannot cross the blood-brain barrier and is therefore incapable of acting as an anti-oxidant in brain tissue. Using this supplement does not result in improvements to memory, mental energy, concentration or mood either.
Some individuals do see positive results when stacking Idebenone tablets with CoQ10 and this is an option you could consider if you have seen good results with this enzyme supplement in the past.
How to Take Idebenone Powder
Most users will consume between 45 mg to 225 mg per day of Idebenone. If you purchase a powdered version of this supplement, it is easy to mix the ingredient into a shake or some other kind of liquid. Idebenone powder is reported to have a very bitter taste by most users so you may want to combine it with a juice or flavoring compound to mask the taste.
Since this is a fat soluble compound, it is best to to take it with food in order to ensure proper absorption. Side effects are minimal when it is used properly, but you should always consult a doctor before you decide to add a new supplement to your diet.
Idebenone offers significant potential benefits for a large number of people. Anyone who is interested in cognitive enhancement or increasing their memory or mental energy should consider this supplement.
It may also be useful for patients who have been diagnosed with depression. Stroke victims may see faster recovery when using Idebenone powder, especially in addressing memory, emotional, and/or speech disturbances. Additional research shows that this compound may be helpful for individuals with Alzheimer’s and specific types of cerebrovascular dementia.
Ultimately, anyone interested in improving their brain power, mood, physical health and longevity of life could see benefits from taking an Idebenone supplement.
- Jaber S, Polster BM. Idebenone and neuroprotection: antioxidant, pro-oxidant, or electron carrier? J Bioenerg Biomembr. 2015
- Houchi H, Azuma M, Oka M, Morita K. Idebenone inhibits catecholamine secretion through its blocking action on Ca2+ channels in cultured adrenal chromaffin cells. Jpn J Pharmacol. 1991
- Gueven N, Woolley K, Smith J. Border between natural product and drug: comparison of the related benzoquinones idebenone and coenzyme Q10. Redox Biol. 2015
- Leonardi A, Crasci' L, Panico A, Pignatello R. Antioxidant activity of idebenone-loaded neutral and cationic solid-lipid nanoparticles. Pharm Dev Technol. 2014
- Brandsema JF, Stephens D, Hartley J, Yoon G. Intermediate-dose idebenone and quality of life in Friedreich ataxia. Pediatr Neurol. 2010
- Latini S, Pedata F, Pepeu G. Effect of idebenone on adenosine outflow and adenine nucleotide level in hippocampal slices under ischemia-like conditions. Eur J Pharmacol. 1993
Article last updated on: April 17th, 2018 by Nootriment
2 Comments
Sounds great… But is there anywhere online that sells idebenone? Please advise.
Supplies are drying up for this prime-of-life-extending wonder drug, possibly related to price increases from China labs. Minimum order stands at 1 KG for about $1,300 U.S. You would think there would be a big enough demand to replenish stocks at the higher prices. Big Medicine patients are cash poor and health-stupid. Big pharma has come out with a couple of branded versions that sell in minimal dose capsules that are 25X bulk powder prices commonly available online before 2017 – about $100/mo. Swann’s has the only affordable but even at 45mg a capsule – the tiny amount of bright orange in a sea of white look more like 10mg in those capsules.