Idebenone is a lesser-known supplement that many experts are recognizing is significantly stronger compared to CoQ10 and offers a wider range of benefits.
Idebenone is a synthetic, shorter chain derivative of CoQ10 which means it is more bioavailable and does not break down as quickly in the body.
This newer formulation can also boost brain health and slow down cognitive aging whereas CoQ10 supplements are not able to cross over into the brain.
What do Idebenone reviews say about how this supplement works? Does it really live up to the claims that it is one of the strongest anti-aging supplements available today?



- Potent anti-oxidant for anti-aging benefits
- Supports ATP production & enegry levels
- Promotes cognitive function & memory
Idebenone Review
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One of the main benefits of CoQ10 is that it is a tremendously powerful anti-oxidant. The same goes for Idebenone.
By targeting free radicals within the brain and the body, this supplement helps to remove poisons and toxins from the body.
It reduces the potential damage that free radicals and oxidation can have on your organs, thereby slowing down the aging process. Idebenone protects organs like the brain, heart, and lungs and may reduce the risk of cancer.
Idebenone Benefits for the Brain
One of the most important benefits of Idebenone is that of enhanced brain health. Idebenone is a nootropic supplement capable of maintaining healthy neurons and nerve function in your cerebral cortex.
This supplement is thought to increase the production of a substance known as nerve growth factor (NGF). This protein within the brain helps to generate, grow, and protect nerves and neuron cells in the brain. Researchers believe that higher levels of NGF can lead to new brain connections, the formation of new synapses, and better overall communication. It boosts plasticity and helps to keep your memory function strong as you age.
Idebenone also leads to increased levels of certain neurotransmitters in the brain. This supplement will enhance Serotonin production, known to help improve mood and feelings of general well-being. Many Idebenone reviews cite the anti-anxiety and mood enhancing benefits of this supplement. This is true, even for individuals who do not get enough tryptophan in their diet which is the main precursor to serotonin.
It also stimulates increased production of Dopamine, Adrenaline, and Noradrenaline – the catecholamine neurotransmitters that regulate mood, energy and arousal. Idebenone accomplishes this by increases the rate of cellular uptake of tyrosine (an amino acid which acts as a precursor for these neurotransmitters).
The effects of higher levels of all these chemicals include increased focus, memory formation and consolidation, improved glucose utilization, and enhanced ATP energy production. It may even help to improve communication between both hemispheres of the brain.
Anti-Aging Results
As is clear from Idebenone reviews posted online, there are also a number of anti-aging benefits associated with this supplement.
This is because Idebenone is able to target oxidative damage in the mitochondria within your brain, heart, and skeletal muscle cells.
This is where the body’s energy production occurs, but this also makes them a major target of free radical damage.
Many researchers think that as mitochondrial reserves become depleted, the effects of aging begin to accelerate. By targeting and scavenging the free radicals here, even under conditions of low oxygen levels, aging may be slowed down and possibly even reversed to some extent.
It is also thought to help improve the blood flow to our various organs, increasing energy production and helping to maintain overall organ function and efficiency.
Idebenone User Reviews:
Many users have reported that they are taking this supplement to help protect their brain and other organs from the effects of aging. Typical benefits include being less tired and feeling like they have more energy. Others report being feeling more motivated, confident and being more productive when using this supplement.
Additional user reviews of Idebenone make mention of having more restful sleep, and reduced feelings of stress, anxiety, and depression. This is likely because of the influence of Idebenone on numerous neurotransmitters. Many of these powerful brain chemicals are known to affect mood and balance out feelings of stress and anxiety.
There have also been reviews indicating improved memory, expanded learning capacity, and improved overall attention and focus. Some individuals have begun using Idebenone in a nootropic stack to help control ADHD and ADD symptoms.
How to Use Idebenone Supplements
According to most reviews, the best dosage range for Idebenone is between 45 and 225 mg per day. This supplement should be taken orally with food, since it is fat soluble. While you could split the daily dose into several administrations, this does not seem to have any improvement in the overall effects.
Always start with the smallest effective dosage to determine how this supplement will affect you before taking larger quantities. If you have used this anti-aging compound, please share your Idebenone review below!
- Brandsema JF, Stephens D, Hartley J, Yoon G. Intermediate-dose idebenone and quality of life in Friedreich ataxia. Pediatr Neurol. 2010
- Zhai H, Cordoba-Diaz M, Wa C, Hui X, Maibach HI. Determination of the antioxidative capacity of an antioxidant complex and idebenone: an in vitro rapid and sensitive method. J Cosmet Dermatol. 2008
- Haginoya K, Miyabayashi S, Kikuchi M, Kojima A, Yamamoto K, Omura K, Uematsu M, Hino-Fukuyo N, Tanaka S, Tsuchiya S. Efficacy of idebenone for respiratory failure in a patient with Leigh syndrome: a long-term follow-up study. J Neurol Sci. 2009
- Parkinson MH, Schulz JB, Giunti P. Co-enzyme Q10 and idebenone use in Friedreich's ataxia. J Neurochem. 2013
- Gueven N, Woolley K, Smith J. Border between natural product and drug: comparison of the related benzoquinones idebenone and coenzyme Q10. Redox Biol. 2015
Article last updated on: April 16th, 2018 by Nootriment
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Is Idebenone available in Australia?