Idebenone supplement were initially developed for the treatment of Alzheimer’s disease and other cognitive defects.
Although this use has met with limited success, it is also currently being investigated for the treatment of neuro-muscular diseases and disorders.
There are many researchers who believe that Idebenone may still prove effective at preventing the onset of Alzheimer’s even if it cannot reverse the damage once it has been done.
From a chemical perspective, this nootropic is an organic compound belonging to the quinone family and a synthetic analog of coenzyme Q10. The major difference between Idebenone supplements and CoQ10 (which you may be more familiar with) is due to their structure.
CoQ10 is considered a long chained compound whereas Idebenone is a short chained compound. This also leads to the fact that Idebenone has a much higher level of bioavailability and that it does not break down nearly as fast due to a lack of oxygen.
Some people describe this compound as CoQ10 on steroids with an even greater range of anti-aging and cognitive enhancement benefits.



- Potent anti-oxidant for anti-aging benefits
- Supports ATP production & enegry levels
- Promotes cognitive function & memory
Idebenone Effects:
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There are two primary mechanisms of action for this supplement. The first of these is by helping to increase something known as nerve growth factor (NGF) within the brain.
Although researchers still do not understand exactly how this chemical works, it is connected with growth, generation, and health of both nerves and neurons.
With higher levels of NGF, this may promote the repair of damaged brain cells as well as stimulate the formation of new connections between neurons and different brain systems.
The transfer of Choline and its associated activity within the brain are also improved while taking Idebenone supplements.
The second primary method by which Idebenone works is as an anti-oxidant. This means that it targets free radicals roaming throughout the brain and body. These are tiny molecules which have become damaged due to exposure to oxygen and could actually target other cells, causing damage to additional cells within the body.
This supplement flushes these free radicals, along with other poisons and toxins, out of the system. In this way, many different organs are protected and Idebenone is described as having a neuroprotective power.
Idebenone Benefits:
One of the best overall health benefits of Idebenone is that of acting as a powerful anti-oxidant.
This means that free radicals and other toxins are removed from the body. This helps to keep the brain healthy and working efficiently.
Incidentally, this does the same things for a number of other organs, which is one of the reasons why anti-oxidants in general are so important to overall health.
The supplement acts as an effective neuro-protectant, guarding against future free radical and other toxin-related damage.
This supplement also has a number of cognitive benefits, mostly related to processes around the brain chemicals Choline and Acetylcholine. These include increased memory and learning/studying capacity. There are also some users who experience a faster speed of memory recall and even greater clarity of thought in general.
Most people will find themselves with a heightened sense of focus, concentration, and possibly even a lengthened attention span. Anyone looking to reduce ‘brain fog’ and experience the ability to think and focus better should consider this supplement.
Another interesting benefit of Idebenone is that of helping to raise Dopamine levels within the brain. This means that many people will experience an overall improved mood and feelings of general well-being. This is understandable since Dopamine is thought to influence processes surrounding mood and movement.
Additionally, Idebenone may help to improve Serotonin turnover, leading to better sleep patterns. It also helps to improve overall brain communication between both hemispheres since it aids information transfer across the corpus callosum area.
Idebenone Dosage:
Most experts will recommend Idebenone supplement users to start at about 500 mg per day.
This dose seems reasonable, although someone who is brand new to Nootropic supplements might want to begin with an even lower dose, at least until they have become familiar with the particular effects upon their body chemistry. The upper end of this daily dosage range would be approximately 1,000 mg.
As with all new supplements, let your own body be the guide and judge accordingly given the specific effects.
Idebenone Side Effects:
Although this supplement has a very safe user profile and it is generally very well-tolerated, there are some common side effects reported.
These include nausea, stomach aches (and other intestinal issues), anxiety, insomnia, loss of appetite, headaches, and possible flu-like symptoms. Additional side effects include possible allergic reactions like facial swelling, itching, or hives. Any of these reactions should lead to medical attention or discontinuation of use.
People who have liver disease, heart problems, or hypoglycemic difficulties (low blood sugar issues) should use this supplement with extreme caution. Rare side effects of Idebenone include lower blood sugar and pressure levels. Users also could see an increase in specific liver enzymes.
Idebenone Review:
Idebenone supplements are one of the best places for a beginner to the world of nootropics to start.
As a highly safe and neuroprotective compound, this nootropic can actually contribute to better brain health for the long term. There are also a number of general health and anti-aging benefits related to the supplement working as a strong anti-oxidant.
It can be stacked, or used together, with your choice of a number of different Choline supplements like Centrophenoxine, CDP Choline, or Citicoline. For an even more powerful boost to memory and focus, consider using Idebenone with one of the Racetams such as Piracetam or Aniracetam.
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Article last updated on: March 13th, 2018 by Nootriment
3 Comments
Hi l need a ldebenon in iran
What can?
Seems IDEBENONE can only be found in a cream or skin application form. Is there a way to purchase this supplement on its own for ingestion?
Whatever you do – don’t try to order it from SmartPowders – total zombie site. Had to resort to disputing the charge with the bank. Zero response after they took my money.
– and pay with PayPal only, so you will have some real recourse.