Using Irvingia gabonensis for weight loss can help to reduce appetite by improving leptin resistance.
Irvingia gabonensis is clinically proven to promote weight loss, reduce weight gain and improve various other adverse health conditions.
It is believed to improve leptin sensitivity, which is sometimes referred to as the “satiety hormone”. This hormone dictates how full you feel after eating a meal, but individuals who are obese tend to be resistant to its effect. This may lead to over-eating as some obese individuals do not feel satisfied after eating a normally portioned meal.
Taking Irvingia gabonensis can reverse the symptoms associated with leptin resistance. Leptin resistance is a primary precursor to Syndrome X (pre-diabetes, metabolic syndrome) and may increase the risks for preventable disease including stroke, hypertension, heart disease, cancer, diabetes mellitus and many others.
Clinical experimentation continues on Irvingia gabonensis as a weight loss aid and natural appetite suppressant. This supplement seems to be particularly effective as a diet pill when combined with Cissus Quadrangularis.



- Helps control the appetite
- Increases leptin sensitivity & adiponectin
- Improves blood sugar & cholesterol
Irvingia Gabonensis for Weight Loss
Irvingia Gabonensis has been demonstrated in several studies to contribute to improved weight management and to support weight loss in obese individuals.
In research trials, using African Mango Extract is associated with improved appetite control, making it easier to achieve a daily caloric deficit which is necessary for weight loss.
In order to lose weight, one must consume fewer calories than one expends during the day in exercise and other activities. Many additional factors can come into play, but if you are eating more calories than you can burn in a day, the additional energy will be stored on the body as fat.
Conversely, if you eat fewer calories than you burn in a day, your body will need to start tapping into its stored fat cells to burn for energy.
Rather than following a fad diet for fast weight loss results, the key to losing weight and keeping it off is adopting lifestyle habits that include eating sensible portions, choosing the right foods and exercising.
However, research shows that individuals who are obese often find it difficult to make the necessary dietary changes because they simply do not feel full after eating reduced calorie meals.
This is a result of hormonal changes that occur when you are obese, specifically affecting the hormone leptin. Irvingia Gabonensis weight loss supplements may be able to combat this overeating by restoring hormone balance so that users feel full after smaller meals and appetite is better controlled.
How Irvingia Helps to Control Appetite
Leptin is an appetite-regulating hormone that is secreted by fat cells (adipocytes) throughout the body. Leptin is released from adipose cells in direct relation to the amount of fat stored by those cells. It is our body’s way of determining exactly how much fat we are carrying so that we can modulate our food needs appropriately.
In normal circumstances, when leptin levels are low, our brain is signalled telling us that we need to find food to meet our energy needs. When levels are high, it tells our brain that we are satiated for the moment and that we do not need to seek out more food immediately. When leptin binds to receptors in the hypothalamus of the brain, hunger signaling is ceased and appetite falls.
However, in some obese individuals, leptin resistance can occur whereby the hypothalamus no longer responds to the presence of this hormone in the same way. Adipocytes are fat storage cells that keep free-circulating fatty acids and hold them to prevent the possibility of starvation in the future.
As an individual continues ingesting more food than what they are burning over time, his or her adipocytes increase in quantity and size.
As leptin is synthesized inside adipocytes, increasing amounts of leptin are produced in relation with increases in adipocyte numbers and sizes.
The adipocytes continue to produce more and more leptin in order to tell the hypothalamus that satiation has been achieved. However, the increased levels of this hormone result in the hypothalamus becoming desensitized to its effects.
The result is leptin resistance, wherein individuals never experience the feeling of satiety or fullness after eating. This can prompt more over-eating and further exacerbate the problem. Irvingia Gabonensis supplements may be able to help by reversing this desensitization process so that normal leptin response is restored.
Results of Irvingia Gabonensis Diet Pills
When taking Irvingia Gabonensis extract for weight loss, research shows that the expression of leptin is downregulated.
Furthermore, studies have shown that it can improve leptin sensitivity and increase levels of adiponectin, which is involved in fatty acid breakdown. By restoring normal leptin functioning, Irvingia Gabonensis can improve the ability of the user to control their appetite.
In one research trial, this was linked to an average 389 calorie deficit per day. In other words, giving subjects I. Gabonensis supplements caused them to naturally eat 389 calories fewer per day compared to the amount of calories that they burned. This study found that using 150 mg dosages every day for 10 weeks resulted in a 6.3% decrease in body fat mass.
Trial participants also experienced an 87% improvement in their ability to control their appetites and saw their waist circumferences drop.
In another study, taking three daily dosages of 1.05 g seed extract from Irvingia Gabonensis over four weeks resulted in 4 kg of weight loss. Participants in this trial were placed on a low fat, low calorie diet that provided 1800 calories per day. While the group that received the Irvingia Gabonensis diet pill lost 4 kg, a placebo group on the same diet plan did not lose weight.
Another study found that test subjects given 150 mg of African Mango extract twice a day for 10 weeks resulted in 12.8 kg of weight loss compared to only 0.7 kg in a placebo group. More research is needed to confirm these results as these studies were conducted by a manufacturer of the product and not by an impartial third party.
There are additional reported benefits from taking Irvingia Gabonensis for metabolism, cardiovascular health and diabetes management. In some studies, this extract was observed to decrease fasting glucose levels, which can help to improve insulin sensitivity and inhibit the storage of fat.
Research has also shown it can improve cholesterol and triglyceride levels and improve parameters related to lipid disregulation in obese individuals.
Irvingia Gabonensis Side Effects and Safety
Irvingia supplements have been deemed as “Possibly Safe”. When side effects are experienced, they are mild and temporary. Flatulence, headaches and sleep disturbances may result from extended or excessive use.
Like all natural dietary supplements, Irvingia gabonensis may not be suitable for use by everyone equally. Pregnant women, nursing mothers, diabetics and surgery candidates should not use this supplement for weight loss without the consent of their doctors.
Concerning dosage, quantities of between 150 mg and 1.03 grams three times daily have been experimented with. These doses were for a standardized I. gabonensis seed extract and geared mainly at weight reduction and improving fatty acid profiling in the body. Due to differences in the strength of extracts sold by different manufacturers, it is important to follow instructions provided on the label of the specific product you purchase.
Always talk with your doctor before beginning any programs for supplementation. Also, healthy levels of exercise, proper nutrition, adequate hydration and effective stress coping all contribute to weight loss and ongoing weight maintenance.
While using Irvingia gabonensis may be effective, best results will always be achieved when paired with appropriate physical activity and dietary interventions.
Article last updated on: May 4th, 2018 by Nootriment