Is Yohimbine HCL Safe Or Dangerous to Take?

Are Yohimbine supplements dangerous? While some research suggests that Yohimbine HCL can be used safely for short periods of time, long-term use could cause serious side effects.

Yohimbine is a chemical that can be isolated from the bark of the Pausinystalia yohimbe tree, a tall evergreen found in Africa.

Yohimbine hydrochloride is a standardized version of this herbal extract that is often consumed as a dietary supplement in order to treat a variety of different conditions.

It is used widely as a dietary supplement for libido and weight loss. However, high doses can result in dangerous adverse effects and Yohimbine HCL is not safe for everyone to take.

Yohimbine

Herbal Supplement

Weight Loss

Energy

Libido

How It Works:

• Helps promote fat loss
• Increases energy & suppresses appetite
• Promotes sex drive & performance

Dosage:

Between 5-50 mg per day

Safety:

Rated Possibly Unsafe

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What Does Yohimbine Hydrochloride Treat?

Yohimbine hydrochloride may be consumed to treat anxiety, depression, dry mouth, erectile dysfunction, orthostatic hypotension and sexual dysfunction.

Some people also take yohimbine to enhance their exercise performance or increase fat loss.

The effectiveness of yohimbine hydrochloride for each of these purposes has been studied by researchers. The results of these studies have been mixed.

For example, while evidence shows that yohimbine hydrochloride is effective in the treatment of sexual dysfunction associated with SSRIs, researchers have not yet been able to find evidence that yohimbine can improve exercise performance.

How it Works

It is important to note that yohimbe and yohimbine are related, but not identical. The term “yohimbe” is used when referring to the tree or its bark.

“Yohimbine,” on the other hand, is a specific alkaloid constituent of yohimbe. According to studies, yohimbe bark contains 6 percent alkaloids, and up to 15 percent of these alkaloids are yohimbine.

Yohimbine HCL is an alpha-2 adrenoceptor antagonist. Alpha-2 adrenoceptors can be found in a variety of locations throughout the central and peripheral nervous system, thus allowing this supplement to affect the body in a number of ways.

Yohimbine HCL increases noradrenaline release, inhibits platelet coagulation, works as an anti-diuretic, increases the release of norepinephrine, dilates the blood vessels in the genitals and increases reflex excitability in the sacral region of the spinal cord.

Is Yohimbine Hydrochloride Safe to Take?

Yohimbine HCL carries some potentially severe side effects when consumed orally.

Yohimbine hydrochloride is regulated as a prescription drug in North America. Research shows that this drug can be used safely for up to 10 weeks under close medical supervision.

Potential side effects of this drug include seizure, myocardial infarction, agitation and cardiac arrhythmia.

Yohimbine HCL may interact with several prescription medications. Major reactions may occur among patients taking this chemical in combination with naloxone.

Moderate reactions may occur among patients taking yohimbine in combination with tricyclic antidepressants, stimulants, phenothiazines, monoamine oxidase inhibitors and guanabenz.

It may also interact with other herbs and supplements, including ephedra, supplements that contain caffeine, berberine or anticoagulant supplements.

Yohimbine Dangers

The side effects of yohimbe and yohimbine HCL may be more pronounced in children. For this reason, children should not consume either of these products.

Yohimbine is also considered unsafe during pregnancy and breastfeeding. These chemicals may cause fetal toxicity and/or have a relaxant effect on the uterus.

How to Counteract Yohimbine Side Effects

Animal studies have shown that the dangerlous side effects of yohimbine HCL may be dose-dependent. Thus, to prevent severe side effects, users should take the minimum effective dosage at all times.

These supplements should be used only while the individual is under the close supervision of a medical professional, and they should not be consumed for any more than 10 weeks at one time.

If a user experiences any potentially severe side effects of yohimbe or yohimbine HCL, he or she should seek medical attention immediately.

Is it safer to consume yohimbe instead of yohimbine? All yohimbe bark extracts contain some amount this alkaloids, so many of the health risks may be the same.

However, because the concentration of yohimbine HCL in these products is often lower, the risk is not as likely to be severe. Nonetheless, users should exercise caution when consuming any yohimbe product.

How to Use Yohimbine HCL Safely

Yohimbine HCL is typically consumed orally. Patients should take this supplement as directed by their doctors and in the smallest effective dosage possible.

While taking this supplement, patients should avoid consumption of foods containing vasopressors, such as chocolate, cola, tea, coffee and overripe fava beans.

Patients should also limit their consumption of foods that contain tyramine, including red wine, fermented meat and aged cheese.

Yohimbine HCL may be dangerous for people who are planning to have surgery or suffer from any of the following conditions:

• Schizophrenia
• Post-traumatic stress disorder
• Liver disease
• Kidney disease
• Hypotension
• Hypertension
• Diabetes
• Depression
• Bleeding conditions
• Benign prostatic hyperplasia
• Anxiety
• Angina
• Heart disease

Safe Dosages of Yohimbine HCL

The best way to prevent dangerous effects from using Yohimbine is to follow dosage guidelines closely. In most cases, severe adverse effects are associated with excess use of this supplement or with combining it with other compounds that result in interactions.

The recommended dosage of yohimbine HCL depends on the patient’s intended usage.

• Sexual dysfunction – 15 to 18 mg of yohimbine HCL daily.
• Orthostatic hypotension – 5.4 mg of yohimbine HCL daily.
• Orgasm improvement – 20 to 50 mg of yohimbine HCL daily in divided doses.
• Erectile dysfunction – 5 to 100 mg of yohimbine HCL daily in up to 4 divided doses.
• Depression – 5 to 30 mg of yohimbine HCL daily.
• Athletic performance – 20 mg of yohimbine HCL twice daily.
• Anxiety – 10 mg of yohimbine HCL once weekly. Often used in conjunction with therapy.

Consult with a doctor before using this herbal extract. Your doctor can help you decide whether Yohimbine HCL is safe or dangerous for you.

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