Using L-arginine for blood pressure treatment may present some strong benefits.
Modern research on L-arginine is addressing its potential to act as a general vasodilator.
This means it can improve circulation while maintaining or even reducing blood pressure.
It has also shown the ability to reduce risk factors for heart attacks and cardiovascular disease. With more than 85 million Americans already having at least one cardiovascular health issue, L-arginine’s capacity to open and relax blood vessels is of paramount interest to scientists.
L-arginine is also beneficial for the following purposes:
- Increasing the volume of blood within vessels without raising blood pressure;
- Healing wounds via increased nutrient, oxygen, protein and hormone delivery;
- Helping the kidneys to eliminate toxic waste products;
- Enhancing hormonal and immune system functioning;
- Relieving angina pain;
- Alleviating symptoms of erectile dysfunction;



- Boosts nitric oxide production for workouts
- Reduces fatigue & promotes muscle growth
- Supports immune function & sexual health
Supplementing with L-Arginine
Related Topics
- L-Arginine
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- Effects on Blood Pressure
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- Arginine Ornithine and Lysine
- Suggested Dosages
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- Best Supplement
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L-arginine is classified as a conditionally essential amino acid.
It is conditional because preterm fetuses are incapable of manufacturing it.
After being born, the human body begins synthesizing all that it needs for its many important biological purposes.
Foods containing appreciable L-arginine supplies include wheat germ, seeds and nuts, red meat, seafood and poultry to name several. Because of its ready availability, and the fact that we make our own, L-arginine deficiencies are not common at all.
However, research shows that in some cases supplementing with therapeutic dosages can result in health benefits.
L-arginine is used to synthesize nitric oxide in the body. NO2 is a neurotransmitter that accommodates the relaxation of blood vessels. When they are relaxed, they open in diameter and allow more blood to pass through without any increased blood pressure.
Some clinical evidence shows that treating patients with L-arginine may cause an increase in blood flow to the heart muscle itself, alleviating symptoms associated with conditions including coronary artery disease, atherosclerosis and more.
L-arginine for Blood Pressure
Although there has not been enough clinical testing conducted for the FDA to approve L-arginine as a treatment for high blood pressure, there are very promising statistics. When there are conditions that cause elevated blood pressure, the internal pressure keeps building and stretching the walls of the vessel.
If not alleviated in time, the vessel can burst outward from the internal pressure buildup. This is the worst case scenario for those afflicted with hypertension. Internal bleeding, hypovolemic shock and death may result.
L-arginine causes the blood vessels to dilate, naturally increasing the rate of flow. It does this without raising blood pressure and may actually be able to lower it to a degree.
L-arginine has also shown clinical promise for its capacity to treat intermittent claudication, a periodic condition of cramping legs with associated weakness.
Besides hypertension, L-arginine is also being investigated as a treatment for certain symptoms and complications associated with type II diabetes mellitus.
L-arginine Food and Drug Interactions
It is possible to experience some food and drug interactions when using an L-arginine supplement.
You should not supplement with L-arginine if you use medications to treat erectile dysfunction or high blood pressure. Do not stack L-arginine with nitroglycerine.
Also, never use L-arginine with medications prescribed to treat the symptoms of herpes. Because this amino acid is an essential constituent of messenger ribonucleic acid (mRNA), it is believed to be able to replicate the herpes virus, and possible others that are already present in the body.
Blood Pressure Control with L-arginine
The actual clinical studies that have been conducted concerning L-arginine for blood pressure regulation have not proven conclusive to the point to recommend it as a standard treatment option.
However, more than enough clinical evidence has been compiled to warrant further, larger-scaled studies.
It is important to remember that even the most effective supplement or pharmaceutical medication is never enough on its own to improve cardiovascular health.
Proper food intake choices, adequate daily physical activity, constant hydration and strong stress coping strategies are all very important too. Making healthy lifestyle modifications is always an integral key toward generating long-lasting good health.
High blood pressure (hypertension) is called the “silent killer”. That’s because, in most cases, the symptoms are so subtle that they go unrecognized until the condition has done irreparable damage.
When you have high blood pressure, it is due to variables that cause constriction within blood vessels and an inability to deliver nutrients, oxygen and other vital constituents successfully to cellular structures.
Calcium, Magnesium and L-arginine
Clinical studies have long proven that adequate levels of magnesium and calcium are integral for keeping blood pressure in check. However, supplementation of these minerals alone has proven basically ineffective at regulating systolic and diastolic blood pressures successfully.
Recent clinical studies are showing promising results for combating hypertension with a conjunction therapy of calcium, magnesium and L-arginine. Again, more studies are necessary, and warranted, to deduce any standardized recommendations concerning the benefits of L-arginine supplementation for hypertension treatment.
For those considering using L-arginine for blood pressure regulation, always consult with your primary physician or alternative healthcare provider before implementation.
- Yeo TW, Lampah DA, Rooslamiati I, Gitawati R, Tjitra E, Kenangalem E, Price RN, Duffull SB, Anstey NM. A randomized pilot study of L-arginine infusion in severe falciparum malaria: preliminary safety, efficacy and pharmacokinetics. PLoS One. 2013
- Suliburska J, Bogdanski P, Szulinska M, Pupek-Musialik D, Jablecka A. Changes in mineral status are associated with improvements in insulin sensitivity in obese patients following L-arginine supplementation. Eur J Nutr. 2014
- El-Hattab AW, Emrick LT, Chanprasert S, Craigen WJ, Scaglia F. Mitochondria: role of citrulline and arginine supplementation in MELAS syndrome. Int J Biochem Cell Biol. 2014
- Lei X, Feng C, Liu C, Wu G, Meininger CJ, Wang F, Li D, Wang J. Regulation of protein expression by L-arginine in endothelial cells. Front Biosci (Schol Ed). 2011
- Mariotti F, Petzke KJ, Bonnet D, Szezepanski I, Bos C, Huneau JF, Fouillet H. Kinetics of the utilization of dietary arginine for nitric oxide and urea synthesis: insight into the arginine-nitric oxide metabolic system in humans. Am J Clin Nutr. 2013
- Popolo A, Adesso S, Pinto A, Autore G, Marzocco S. L-Arginine and its metabolites in kidney and cardiovascular disease. Amino Acids. 2014
- Abd El Dayem SM, Battah AA, El-Shehaby A, El Bohy Ael M. Asymmetric dimethyl L-arginine, nitric oxide and cardiovascular disease in adolescent type 1 diabetics. J Pediatr Endocrinol Metab. 2014
- Tang JE, Lysecki PJ, Manolakos JJ, MacDonald MJ, Tarnopolsky MA, Phillips SM. Bolus arginine supplementation affects neither muscle blood flow nor muscle protein synthesis in young men at rest or after resistance exercise. J Nutr. 2011
- Polycarpou E, Zachaki S, Tsolia M, Papaevangelou V, Polycarpou N, Briana DD, Gavrili S, Kostalos C, Kafetzis D. Enteral L-arginine supplementation for prevention of necrotizing enterocolitis in very low birth weight neonates: a double-blind randomized pilot study of efficacy and safety. JPEN J Parenter Enteral Nutr. 2013
Article last updated on: May 13th, 2018 by Nootriment
1 Comment
how can I get a copy of this report for my doctor? thanks