Lactobacillus Paracasei Probiotic Benefits for Weight Loss & More

Lactobacillus Paracasei is a strain of probiotic bacteria that is said to improve fatigue and dental health. This lactic acid-fermenting bacteria (LAB) is a natural component of the microflora of the gut.

Research shows that the average adult human has over 100 trillion bacterial microroganisms living in the intestinal tract, colon, urogenital tract, mouth and on the skin.

Probiotic bacteria have a positive effect on our health and prevent the proliferation of pathogenic bacteria, which can spread disease.

The L. paracasei strain of probiotic is one of the 400 different species that exist naturally in the body. This strain is involved in digestive function, supporting the immune system and in fighting the growth of bacteria in the mouth.

It has also been used to improve energy and for symptoms of Chronic Fatigue Syndrome (CFS).

This probiotic supplement also have a chemoprophylactic effect and is said to help fight infections. Two substrains of Lactobacillus paracasei have been found to inhibit the growth of Salmonella enterica and Heliobacter pylori in the gastrointestinal tract.

Probiotics

Digestive Supplement

Gut Health

Digestion

Immune Function

How It Works:

• Supports a healthy immune system & microflora
• Promotes digestion & nutrient absoprtion
• Combats pathogenic bacteria; Improves metabolism

Dosage:

Between 1 - 10 Billion CFUs per day

Safety:

Rated Likely Safe

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What is Lactobacillus Paracasei?

Lactobacillus paracasei is used in fermented milks and cheese and is also found in fermented vegetables and meat. Lactobacillus paracasei occurs naturally in the human intestinal tract.

This probiotic strain is closely related to Lactobacillus casei. The name Lactobacillus casei refers specifically to two strains that are denoted by the identifiers ATCC 393 and NCFB 173. Other Lactobacillus caseistrains are classified as Lactobacillus paracasei subsp. paracasei.

Lactobacillus paracasei inhibits enteric pathogens and improves the immune system. This probiotic strain also inhibits tooth decay. Lactobacillus paracasei has anti-obesity applications and helps respiratory infections and reduces allergic responses.

Lactobacillus paracasei benefits

L. paracasei is a probiotic that is primarily found in the mouth and gastrointestinal tract. Eight strains of this species have been identified in the microbiome of the gut.

This probiotic has good survivability in stomach acid following oral ingestion. This is important as some strains of probiotic bacteria can be heavily broken down when they reach the acids in the stomach. After passing into the intestines, this probiotic bacteria can confer its purported beneficial effects.

Lactobacillus paracasei has an 80-90% survival in hydrochloric acid and pepsin at pH 3 for 1h at 37ºC. The Bile salt (small intestines) tolerance resistance is less than 60% survival and the Pancreatin survival rate is more than 60 percent.

L. paracasei is listed in the Inventory of Microorganisms With Documented History of Use in Human Food. This probiotic strain is also on the Qualified Presumption of Safety list with the European Food Safety Authority.

Effects of Lactobacillus Paracasei

One of the effects demonstrated by this probiotic bacteria is a chemoprophylactic effect.

This means that it helps to prevent disease or infection by supporting the immune system function. L. paracasei does this by inhibiting the spread of pathogenic (bad) bacteria.

In laboratory studies, Lactobacillus paracasei has been shown to inhibit the enteric pathogens Salmonella typhimurium, Staphylococcus aureus, Escherichia coli (E. Coli) (E. Coli) and Listeria monocytogenes. These bacteria are associated with infections and foodborne diseases.

L. paracasei Lpc-37 has been shown in laboratory studies to provide good adhesion to the human epithelial intestinal wall. This ability gives this probiotic strain a better chance to modulate the immune response. It may also protect against enteric pathogens by limiting their ability to colonize the intestine.

A clinical study published in The American Journal of Clinical Nutrition in June 2015 showed probiotics can modulate the immune system and may reduce symptoms related to respiratory infections.

The subjects in the study were randomly assigned to receive an acidified milk drink containing 10 million colony-forming units of L. casei 431 or placebo for 42 days. After 21 days, subjects received the seasonal influenza vaccination.

Daily consumption of L. casei 431 (Lactobacillus paracasei subsp. Paracasei) resulted in no observable effect on the components of the immune response to influenza vaccination. But there was a reduction the duration of upper respiratory symptoms.

Additional Uses for Lactobacillus Paracasei

This species of Lactic-Acid producing bacteria has also been recommended for dental health and is sometimes used to fight cavities.

In animal clinical studies with rats Lactobacillus paracasei subsp. paracasei NTU 101 showed it may help to protect against cavities. It works by reducing oral levels of Streptococcus mutans, which is one of the main bacteria associated with tooth decay.

The supplement has also been recommended for supporting weight loss diets. The substrain Lactobacillus paracasei F19 was studied by researchers associated with the Karolinska Institutet in Sweden. They studied mice for 10 weeks on a diet of 20% fat; half of the mice were given Lactobacillus paracasei F19 and the other half were given a control.

The group given the probiotic gained less weight and had significantly lower total body fat than the control group. The researchers also found four times more FIAF hormone (Fasting Induced Adipose Factor) in the blood of the mice that had been given the probiotic.

FIAF inhibits the enzyme LPL (Lipoprotein lipase) which fat cells use to absorb fatty acids in the blood. To achieve weight loss results cooled products as opposed to heat killed Lactobacillus paracasei F19 products need to be used.

The amount of VLDL (Very low-density lipoprotein) triglycerides in the blood does rise as a result of taking Lactobacillus paracasei F19 but the overall cholesterol did not increase.

A clinical study in Frontier of Microbiology in September 2015 showed Lactobacillus paracasei LPC-S01 (DSM 26760) was suitable for treating conditions such as BV (Bacterial vaginosis).

This probiotic was effects in the form of a vaginal suppository. This study also showed that this probiotic could be taken orally as an effective gastrointestinal probiotic.

Other studies have showed supplementing with probiotics can protect against the development of food allergies by modulating the host immune response.

One clinical study investigated the allergy-reducing effects of regulatory dendritic cells (regDCs) (antigen cells of the immune system) induced by Lactobacillus paracasei L9 (L9) in beta-lactoglobulin (BLG)- sensitized mice.

The clinical study data concluded that Lactobacillus paracasei L9 (L9) reduced the BLG allergic sensitization. It is thought this is because this supplement activated suppression of the regDCs.

Is Lactobacillus Paracasei Safe?

Lactobacillus Paracasei is naturally found in foods that we eat and exists naturally in the human body. It is safe to supplement with for most individuals, but there are some who should not use probiotics.

Probiotic supplements should be avoided by those with impaired immune systems such as organ donors and those using a catheter. People with open surgical wounds should also avoid using probiotics.

Immuno suppressant medications such as cyclosporine (Neoral, Sandimmune), tacrolimus (Prograf), azathioprine (Imuran), and cancer chemotherapeutic agents like cyclophosphamide (Cytoxan) and cisplatin (Platinol-AQ) should also not be taken with probiotics.

Antibiotics do interact with probiotics and should be taken at least two hours apart from each other. People with milk allergies or lactose intolerance should also avoid milk based probiotics.

Taking probiotics during pregnancy or breast feeding should only be done under medical advice from a health care professional.

Lactobacillus paracasei has applications for oral health, the treatment of BV and infections, reducing intestinal inflammation, treating respiratory conditions and improving immunity as well as a role in weight loss.

It is safe for most individuals, but speak to your doctor before using this or any supplement to make sure it is appropriate for you.

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