Lecithin Side Effects, Safety Review & Drug Interactions

What are the possible negative side effects that can occur when using Lecithin supplements or granules? Lecithin is a phospholipid found in many natural foods and in the form of an oral, intravenous or topical supplement.

According to the Natural Medicines Database, lecithin supplements may be taken for a number of purposes, ranging from supporting cognitive function to improving acne.

Although this supplement has been well tolerated in past research studies and is considered to be likely safe when taken appropriately, it may still cause side effects for some people. In addition, lecithin supplements may interact with other medications, and they are contraindicated in certain populations.

Below is some basic information about lecithin as a supplement, its uses and effects, lecithin side effects and taking lecithin safely.

Lecithin

Nutrient Supplement

Brain Health

Memory Function

Metabolism

How It Works:

• Natural source of Phosphatidyl Choline
• Provides nervous system support
• Promotes memory function & brain cell health

Dosage:

Between 1 - 35 g per day

Safety:

Rated Likely Safe

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How Does Lecithin Affect the Body?

Research has shown that lecithin may affect the body in a range of ways. Some of the possible effects of lecithin include:

• Respiratory effects – Research has shown that lecithin may improve asthma symptoms.
• Antitumor effects – Lecithin may have a cytotoxic effect on certain types of cancer cells.
• Effects on the liver – Lecithin may protect the liver from certain types of damage.
• Cognitive effects – Some studies have shown that lecithin has a positive effect on memory and brain function.

Lecithin may also affect the growth and quality of skin and hair, the absorption of cholesterol and the release of certain stress hormones.

What is Lecithin Used for?

According to the Natural Medicines Database, lecithin is used for a range of purposes, including cognitive disorders, skin issues, gallbladder disease and various psychiatric conditions.

Although research has shown that lecithin supplements may be effective for some of these purposes, the FDA has not approved this natural product as a medicine for the treatment of any health conditions.

Is Lecithin Safe?

Oral lecithin supplements are considered likely safe when they are used appropriately. Likewise, intravenous, subcutaneous and topical preparations of lecithin are believed to pose a low risk of side effects.

As a food ingredient, this product has achieved “Generally Recognized as Safe” status in the United States. This means that the US Food and Drug Administration believes that Lecithin is well tolerated by the majority of users and is not likely to cause serious negative effects.

However, these supplements may still cause adverse reactions in some consumers, so it is important to exercise caution if you decide to take lecithin.

Lecithin Side Effects

Some people may experience temporary side effects while taking lecithin dietary supplements.

The most common side effects are gastrointestinal in nature and tend to be mild. However, some people may also experience other, more severe side effects.

Lecithin Adverse Effects on the Thyroid

Certain types of this phospholipid, including lecithin derived from soy, may have an affect on the thyroid gland.

Studies have shown that unfermented soy may contain plant estrogens and toxins capable of damaging the thyroid.

According to the website Natural News, unfermented soy may even contribute to the development of hypothyroidism and/or thyroid cancer. Soy may also inhibit the uptake of iodine, an essential element.

Allergic Reactions

Some consumers may have an allergic reaction while taking lecithin granules or powder. For example, if you are allergic to soy, you may have a reaction to soy-based lecithin supplements.

Before taking this supplement, read the packaging to determine whether you might be allergic to any of the supplement’s sources or ingredients.

If you experience the symptoms of an allergic reaction, such as hives or difficulty breathing, stop taking the supplement and seek medical treatment.

Lecithin Interactions and Contraindications

Lecithin is unlikely to interact with prescription medications or other supplements, with the exception of diclofenac. Other undiscovered interactions may still exist, however.

At this time, it has not been found to exacerbate any existing diseases or conditions. However, because of a lack of available information, women who are pregnant or breastfeeding should avoid using lecithin supplements.

How to Take Lecithin Safely

In order to avoid any potential negative effects of lecithin, it is important to take the supplement according to manufacturer guidelines or as directed by your physician.

Standardized dosing guidelines for lecithin are not available. However, a range of dosages has been used in research studies with little to no adverse effects. These dosages include:

• Dementia – Up to 1,600 mg daily for three months.
• Enhanced athletic performance – 2.2 grams daily.
• Alzheimer’s disease – 10 to 25 grams daily for up to six months.
• Total parenteral nutrition – 40 grams daily for six weeks.
• Tardive dyskinesia – 20 to 50 grams daily for up to eight weeks.
• Stress – 400 mg of soy lecithin phosphatidic acid and phosphatidylserine complex three times daily for two months.
• Parkinson’s disease – 32 grams daily for nine weeks.
• Mania – 10 grams three times daily.
• Lipid lowering – 550 mg of lecithin three times daily.

Lecithin supplements are available in several different forms, including powders, capsules, granules and topical preparations. The form you choose may affect the concentration of the active ingredient and, thus, the proper dosage. If you aren’t sure how much lecithin you should take, consult your doctor.

Even though most people have taken lecithin without serious side effects, adverse reactions are still possible. If you experience severe or bothersome negative effects, stop taking the supplement and talk to your doctor.

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