Nefiracetam holds a special place among the Racetam category of nootropics, known for increasing the uptake of the nutrient choline into neurons.
This enhanced neuronal choline utilization leads to improvements in cognitive ability and brain power.
While Nefiracetam is not as popularized as supplements like Piracetam or Aniracetam, it has garnered a lot of attention for possible implications in treating Alzheimer’s and cognitive decline.
Nootropic users are starting to seek out Nefiracetam to use in their smart drug stacks and are reaping significant rewards. What do reviews say about this supplement and what are some of the typical facets of the Nefiracetam experience?



- Promotes brain health & communication
- Supports memory, reasoning & cognition
- Boosts focus, mental clarity & attention
Nefiracetam Review
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Nefiracetam is a derivative of the first Nootropic, Piracetam, but is considered to have more in common structurally with Aniracetam.
As a fat soluble supplement, Nefiracetam has excellent transportation across the blood-brain barrier and is reasonably fast acting.
Once it begins to interact with your neurons, it increases the efficiency of mental processing and memory formation.
First, blood flow to the brain is enhanced. This tends to increase mental energy as more oxygen and glucose are delivered to your neurons.
Nefiracetam is also the only known nootropic to increase the rate at which Choline is taken up by your neurons. This nutrient is closely related to the B Vitamin family and is necessary for your brain to make the neurotransmitter acetylcholine.
Considered to be one of the most important excitatory neurochemicals, this signaler facilitates memory encoding, consolidation and retrieval as well as helping the brain focus and block out distracting stimuli.
The more acetylcholine your brain produces, the more plastic your brain is and the better able you are to learn, recall memories, focus, and reason logically.
The rate-limiting factor in how much acetylcholine your neurons produce has to do with how much choline makes it into your neurons. By making it easier for your brain cells to take up this nutrient, Nefiracetam can have a profound impact on acetylcholine activity in the hippocampus and related brain systems.
Another important qualification for a supplement to be considered as a Nootropic is that it should ideally have some ability to help protect the brain. This is indeed the case with Nefiracetam, as it is capable of protecting neurons from damage which can decrease choline update.
It seems to be especially effective at guarding the area of the brain known as the hippocampus, which is a member of the limbic system and plays important roles in both long-term memory formation and spatial navigation.
Nefiracetam is thought to potentially be able to reverse damage caused by excessive alcohol as well as other forms of environmental stress. Furthermore, Nefiracetam can protect neurons from undergoing premature cell death in the presence of other neurotoxins.
This supplement is also reported to be quite effective in treating seizures. It has been used clinically for this very purpose for many years, taken by patients with both convulsive and non-convulsive types of seizures. When used immediately prior to, or during, a stroke it can greatly reduce the number and duration of seizures that may occur after the event.
What To Expect From Nefiracetam:
The Nefiracetam experience is typified by an increase in memory, learning capacity, and speed of cognition. Many users say that taking Nefiracetam results in dramatic improvements to memory retention when studying new information.
You may find that you seem to grasp all details without trying and do not have to review material as much for it to sink it. Some users will experience a faster speed of recall, as if they always have the right answer readily accessible in their mind.
Many report that they experience colors and sounds in an entirely new way, with more depth, clarity, and brilliance
Students find this to be a very helpful study aid. They notice an increased amount of mental energy (most likely due to the increased cerebral blood flow) and ability to focus and concentrate.
Not only that, but mental fluidity is improved. This means that tasks like reading and writing seem to flow more easily and can be accomplished with much less conscious effort.
Nefiracetam reviews also frequently mention that it is much easier to deal with conditions like ADD and ADHD on this supplement. You may find that you are not easily distracted and can block out unhelpful or distracting thoughts.

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How To Take Nefiracetam:
The best way to use Nefiracetam is by splitting up your total daily use into several different equally divided administrations.
Most experts suggest taking your 150 to 450 mg dose in three shots, normally with a meal since it is fat soluble.
The reason for the split doses is due to the fact that this supplement is very fast acting, reaching and affecting the brain within 30 to 60 minutes.
Additionally, due to the half-life, these frequent doses enable the active ingredients to remain in a more or less consistent supply/level throughout the day.
Nefiracetam Toxicity & Safety:
As far as toxicity of this supplement, studies have indicated that humans can safely take up to 900 mg of Nefiracetam on a daily basis. Most experts think that there would still not be any toxicity at even higher dose levels, though rigorous clinical trials have not yet been conducted to establish an upper limit.
There are some mild side effects associated with this supplement. These include headaches (can be relieved by the inclusion of a Choline supplement), nausea, irritability, fatigue, dizziness, and stomach issues.
Most Nefiracetam experience logs do not contain mention of side effects and they are generally the exception rather than the norm.
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Article last updated on: March 13th, 2018 by Nootriment