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Neurocetam is a brand of Piracetam or Nootropil sold by Micro Labs, Brown & Burk Phils Inc. It is sold in the form of 400 mg, 800 mg and 1200 mg tablets as well as 500 mg/mL syrup and a 200 mg injection.
There is also a Neurocetam Plus tablet, which contains 800mg of Piracetam with 500mg of Citicoline (CDP Choline).
Neurocetam use is indicated for the treatment of cognitive dysfunction, memory loss due to Alzheimer’s disease and Dementia, stroke recovery and to slow down brain degeneration caused by aging.
This nootropic drug has been shown to promote memory and learning, increase blood flow to the brain, and support alertness and brain cell health.
In addition to its medical use, Piracetam is also taken as a cognitive enhancer for healthy adults. It is purported to boost mental performance and has a low risk of side effects compared to other widely used smart drugs.
Memory
Attention
Brain Health- Promotes neuron health & synaptic plasticity
- Supports memory recall & learning
- Boosts focus, visual perception & attention
Neurocetam Review
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Neurocetam is manufactured by Micro Labs and is distributed in India, the Philippines and other countries in Asia.
In addition to those uses mentioned above, it is prescribed for the treatment of myoclonus, dyslexia, Down’s syndrome, vertigo, epilepsy, motion sickness, Raynaud’s disease, sickle-cell anemia, alcohol withdrawal, Parkinson’s disease and a number of other conditions.
It is used clinically in the UK, Russia, Europe, South American and parts of Asia. Neurocetam has not been approved for use in Canada, the United States or Australia.
It is also used off-label to enhance brain function, neuron health and memory. It appears to ameliorate cognitive deficits under certain conditions causing impairment.
The active ingredient in Neurocetam is Piracetam, which was the original nootropic agent discovered in 1964 by Dr. Corneliu E. Giurgea. It was given the name “nootropic” in recognition of its ability to promote neurological function without the side effects seen with stimulants or sedatives.
Piracetam (2-oxo-1-pyrrolidine-acetamide) is a cyclical derivative of GABA (gamma-aminobutyric acid) and has a pyrrolidine core, like all members of the Racetam family of drugs.
This nootropic agent is described as having neuroprotective properties, which means that it may help to protect brain cells against certain forms of damage and degeneration. In particular, it appears to restore cell membrane fluidity and protect neurons from damage caused by hypoxia (insufficient oxygen).
Studies have also shown Piracetam to improve neuroplasticity through its effects on cholinergic and glutamatergic neurotransmission. Neuroplasticity refers to the ability of neurons in the brain to adapt, grow and form new connections.
Use of Neurocetam is believed to be effective for slowing down some forms of brain function degeneration as we age. It is also used in healthy adults to promote learning, attention, intellectual processing, reasoning, stable mood and mental alertness.
- Promotes neuron health & synaptic plasticity
- Supports memory recall & learning
- Boosts focus, visual perception & attention
Effects & Benefits
How piracetam works is not completely understood. Scientific study has identified several mechanisms of action.
It appears to increase the function of the neurotransmitter acetylcholine by facilitating activation of muscarinic cholinergic (ACh) receptors. It is also believed to increase glutamate receptor activation, thereby promoting memory function and long-term potentiation.
Additional mechanisms include increasing oxygen consumption and circulation to neurons as well as increasing membrane fluidity changes in EEG activity. Piracetam can also increase levels of monoamine neurotransmitter release and turnover and has been shown in animal studies to affect dopamine, serotonin and norepinephrine activity.
Preliminary findings suggest that the effects of Neurocetam on brain function are steroid-dependant. Studies have shown that long-term administration of this nootropic drug can cause small increases in plasma corticosterone levels and that the effects of Piracetam on memory are blocked by corticosteroid receptor antagonists.
As the first nootropic ever discovered, it is the most widely researched of the racetam compounds. However, it also has the lowest potency and requires a large dosage to experience beneficial effects.
Other nootropic drugs in clinical use today are 10 – 100 times more potent than Neurocetam. This nootropic is well-regarded for tolerance and safety.
How to Use
Follow the directions of the doctor who prescribed Neurocetam to you for information on dosing and how to take.
Neurocetam is available in an oral tablet, liquid syrup or as an injection. The injectable form is typically only used in a medical setting for the treatment of ischemic stroke patients.
The tablets provide either 400mg, 800mg or 1200mg of the active ingredient Piracetam per pill. They can be taken with or without food.
The standard therapeutic dosage is between 1,200 – 9,600mg per day. The correct dosage will depend on the reason this medication is being taken as well as whether any other medications are being used concurrently.
Some individuals experience a headache when taking Piracetam as a nootropic supplement. Your doctor may recommend the use of a choline supplement like CDP Choline or Alpha GPC to be taken alongside your dosage.
Toxicology data from animal studies shows a low risk of overdose. However, it is important to not take more than the recommended dosing to reduce the likelihood of side effects.
Neurocetam Plus Review
Neurocetam Plus is another form of this smart drug sold by Micro Labs in India. It combines 800mg of Piracetam with a 500mg dosage of Citicoline (CDP Choline).
Citicoline is a phospholipid-bound form of the dietary nutrient choline, which is the precursor to the neurotransmitter acetylcholine.
Your brain needs sufficient stores of choline in order to make this neurotransmitter. Furthermore, this molecule can also be incorporated into neuron membranes as a phospholipid.
Neurocetam is believed to cause more acetylcholine to be released from your neurons. Depletion of this neurotransmitter may reduce the efficacy of this drug and is theorized to result in headaches.
Taking Piracetam with a form of choline supplement may have synergistic benefits, resulting in greater cholinergic activity and a lower frequency of headaches.
Citicoline is also used independently as a drug for the treatment of neurological symptoms in patients following an ischemic stroke. It has also been prescribed for treatment of head trauma, cognitive disorder, Parkinson’s disease, non-progressive neuromotor dysfunction and age-related memory decline.
Citicoline has a number of nootropic benefits on its own and is purported to enhance memory, focus, attentional control, brain health and act as a neuroprotective agent.
Consult with your doctor about whether the single-ingredient Neurocetam capsules or the Neurocetam Plus tablets are a better choice for your needs.
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Side Effect
Neurocetam is generally regarded as well-tolerated and is safe when taken under the supervision of a medical professional. This cognitive enhancer is non-toxic and has not been reported to cause any dangerous side effects.
Some users can experience side effects, particularly when they first start taking this medicine. The most commonly reported adverse effects are headache, nervousness, abdominal pain and anxiety.
Other rare side effects reported include skin rash, nausea, confusion, depression, diarrhea, hallucination, muscle spasm or uncontrollable movements, insomnia and sleep disturbances, sleepiness, vertigo, vomiting, muscle weakness, instability while walking and weight gain.
In extremely rare cases, it may cause breathing difficulties or swelling of the face, lips, tongue, eyelids, hands or feet. Discontinue use and contact your doctor immediately if you experience these symptoms.
This drug can affect platelet aggregation and may increase the risk of bleeding and bruising. It should not be used by individuals taking anti-coagulant or anti-platelet medications such as warfarin or aspirin.
Some brands of this drug may contain sodium in the tablets or the syrup. Take this into account if you have been prescribed a low-sodium diet for hypertension or another related condition.
Be cautious if combining this drug with alcohol use. It may cause the intoxicating effects of alcohol consumption to be more potent, resulting in lower tolerance. Exercise caution before driving or operating heavy machinery.
No human studies have been conducted on the use of Piracetam in pregnant or lactating mothers. It is recommended to avoid this nootropic drug out of a lack of sufficient information on its safety.
When taken orally, this drug gets transmitted into breastmilk. Breastfeeding mothers who require this medication may need to bottle-feed their children instead.
Individuals diagnosed with kidney disease should exercise caution when taking this medication. Your doctor may recommended a smaller daily dose, depending on your current kidney function analysis.
Use of Neurocetam tablets in patients with liver disease is not contraindicated. Some research suggests that dose adjustment is not required, but your doctor may decide to give you a smaller dose if you have a history of liver problems.
Do not take any form of Neurocetam or Piracetam if you are allergic to ingredients in this product. Do not use if you have Huntington’s disease, brain hemorrhage, bleeding disorders or are scheduled to undergo surgery in the next two weeks.
Neurocetam tablets may worsen symptoms in patients diagnosed with Huntington’s chorea.
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Article last updated on: July 17th, 2018 by Nootriment