1
4.11
5
The Noopept Choline stack combination is common among nootropics users seeking the benefits of cognitive enhancement with low incidence of known side effects.
In this stack, Noopept is used to increase concentration, enhance learning capacity and to hone reasoning skills. For some people, it also offers heightened perceptual awareness.
Choline supplementation is combined with Noopept to potentiate its function in the brain and to reduce onset of headache sometimes brought on through acetylcholine fatigue. Choline has been reported by some to have positive effects on mood.
Noopept and Choline work well together to enhance mental clarity, increase both short- and long-term memory, clear brain fog and give the user an overall cognitive boost.
Mental Energy
Memory
Brain Health- Supports memory, focus & mood
- Boosts mental alertness & energy
- Increases BDNF & promotes brain health
Noopept and Choline Breakdown
Related Topics
- What is Noopept?
- User Reviews
- Reported Benefits
- How it Works
- Negative Side Effects
- Typical Experiences
- Recommended Dosage
- Best Way to Take
- Stacking with Choline
- Recommended Nootropic Stacks
- Purchasing Guide
- Bulk Noopept Powder
- Buy Noopept Capsules
- Is Noopept Legal?
- Comparison to Piracetam
- Comparison to Aniracetam
- Comparison to Oxiracetam
- Comparison to Pramiracetam
Produced and widely prescribed in Russia for certain neurological disorders, the peptide Noopept is in the racetamic family and more than 1,000 times stronger than other racetams.
This allows Noopept to be used in significantly smaller doses with the same degree of effectiveness.
Noopept primarily affects the neurotransmitter Glutamate, while other racetams work primarily on Acetylcholine. A majority of users compare the effect to that of Piracetam or Aniracetam.
Choline is a frequent supplement in many nootropic stacks for good reason. It is an essential nutrient for maintaining the integrity of cell membranes and is an important precursor to Acetylcholine. Acetylcholine is a neurotransmitter mostly involved with, and necessary for, memory function.
Over 85% of people are estimated to be Choline deficient. Choline deficiency can result in an inability to concentrate, mood instability and memory deficits. Choline is often paired with Noopept to improve each of these functions.
Noopept users sometimes experience headaches which are likely associated with increased Acetylcholine activity in the brain. Using a quality source of Choline to provide the brain with the material it requires seems to mitigate this side effect.
Benefits
Combining Noopept with Choline can create a noticeable synergistic boost in brain function. Students report an increase in their learning ability while experiencing greater ease with both long- and short-term memory.
Focus, attention and clarity are frequently enhanced, and many people experience an elevation in mood. This combination has helped users with concentration and enhances memory absorption and recall. Users have also reported Noopept having a slight anti-anxiety effect.
Studies have shown Noopept also acts in a neuroprotective capacity by preventing damage to the brain caused by oxidative stress and apoptosis in human neurons.
In rodent studies, this nootropic showed an effect on nerve growth factor (NGF) and brain-derived neruotrophic factor (BDNF). In rodents, both NGF and BDNF were increased. These are both important players in the role of long-term memory, as well as the growth and protection of new specialized neurons and synapses.
Memory Brain Health
Cognition- Supports memory and synaptic plasticity
- Raises acetylcholine levels
- Promotes brain health and focus
Top Choline Products* ❯Noopept Choline Stack Dosage Ratio
Noopept Dosage: Noopept comes most commonly in powder form. It works best when taken at the recommended dosage of 10-30 mg over two to three intervals throughout the day. Users should start at the lowest dosage and adjust up only if necessary. Do not use a mega-dose unless you have extensive experience taking it as normal administration quantities first.
Many users reap the same benefits with 10 mg as they do with 30 mg. Noopept will build in the system over time and benefits will become more evident. Noopept is fat soluble and seems to work well when taken with a high protein meal. Some users have reported a more immediate and potent effect when taking the powder sublingually. Effects are usually noticed after a 5-7 day usage.
Choline Dosage: It is important to understand the differences between Choline types and to choose one which offers the level of bio-availability desired. Alpha GPC and Citicoline are able to cross the blood-brain barrier in significantly greater quantities and thus are more bio-available for the purpose intended.
Because of this, dosage requirements are often lower than with other Choline sources. Other Choline supplements are Choline Bitartrate (a salt) and PhosphatidylCholine powder.
If you do decide to use a Noopept Alpha GPC stack, it is common to take about 20x more Alpha GPC choline than Noopept. For example, a dosage of 20 mg of Noopept powder might be combined with 400 mg of Alpha GPC. When stacking Noopept and Citicoline (CDP Choline) together, a more common dosage ratio is 1:30.
This means if you were to use 20 mg of Noopept, you would use approximately 600 mg of Citicoline over the course of a day. You may find the need to personalize this ratio depending on your current diet and other factors. Some choline-dominant individuals may see results at much lower dosages for the Noopept Choline stack. You may also want to add other ingredients to this stack such as Piracetam or even Modafinil.
- 1000x more potent than Piracetam
- Supports memory, focus and mood
- Boosts mental alertness and energy
Side Effects
Side effects for this stack are typically low if staying within dosage recommendations. The headache which some people experience due to increased Acetylcholine activity are usually offset when taken in combination with a good Choline source.
There may be some tolerance and decreased effect if Noopept is used over the long-term. It is recommended to cycle this nootropic, for example 3 months on and 1 month off. The half-life of Noopept is not known.
Review
The Noopept Choline stack is a good choice and may be best for those already experienced with racetam use and effect. Users should pay particular attention to dosage and should cycle this stack to reduce the occurrence of tolerance.
There may be long-term positive neural effects but further studies are needed. People taking this stack or any other Noopept supplement stack should be aware that long-term use has not been studied in humans at this time.
The combination of Noopept and Choline in a stack together can be both a cognitive and mood booster.
- Focus longer, clear brain fog & feel more motivated
- Boost energy, alertnes & memory
- Contains 12 safe and natural nootropic ingredients
- Boeke CE, Gillman MW, Hughes MD, Rifas-Shiman SL, Villamor E, Oken E. Choline intake during pregnancy and child cognition at age 7 years. Am J Epidemiol. 2013
- Strain JJ, McSorley EM, van Wijngaarden E, Kobrosly RW, Bonham MP, Mulhern MS, McAfee AJ, Davidson PW, Shamlaye CF, Henderson J, Watson GE, Thurston SW, Wallace JM, Ueland PM, Myers GJ. Choline status and neurodevelopmental outcomes at 5 years of age in the Seychelles Child Development Nutrition Study. Br J Nutr. 2013
- Dong Z, Fu A. Prevention of age-related memory deficit in transgenic mice by human choline acetyltransferase. Eur J Pharmacol. 2012
- Biasi E. The effects of dietary choline. Neurosci Bull. 2011
- da Silva RP, Kelly KB, Lewis ED, Leonard KA, Goruk S, Curtis JM, Vine DF, Proctor SD, Field CJ, Jacobs RL. Choline deficiency impairs intestinal lipid metabolism in the lactating rat. J Nutr Biochem. 2015
- Fischer LM, da Costa KA, Kwock L, Galanko J, Zeisel SH. Dietary choline requirements of women: effects of estrogen and genetic variation. Am J Clin Nutr. 2010
- Lavery AM, Brender JD, Zhao H, Sweeney A, Felkner M, Suarez L, Canfield MA. Dietary intake of choline and neural tube defects in Mexican Americans. Birth Defects Res A Clin Mol Teratol. 2014
- Ostrovskaya RU, Vakhitova YV, Kuzmina USh, Salimgareeva MKh, Zainullina LF, Gudasheva TA, Vakhitov VA, Seredenin SB. Neuroprotective effect of novel cognitive enhancer noopept on AD-related cellular model involves the attenuation of apoptosis and tau hyperphosphorylation. J Biomed Sci. 2014
- Ostrovskaya RU, Romanova GA, Trofimov SS, Gudasheva TA, Voronina TA, Halikas JA, Seredenin SB. The novel substituted acylproline-containing dipeptide, GVS-111, promotes the restoration of learning and memory impaired by bilateral frontal lobectomy in rats. Behav Pharmacol. 1997
- Amelin AV, Iliukhina AIu, Shmonin AA. [Noopept in the treatment of mild cognitive impairment in patients with stroke]. Zh Nevrol Psikhiatr Im S S Korsakova. 2011
- Neznamov GG, Teleshova ES. Comparative studies of Noopept and piracetam in the treatment of patients with mild cognitive disorders in organic brain diseases of vascular and traumatic origin. Neurosci Behav Physiol. 2009
- Romanova GA, Shakova FM, Gudasheva TA, Ostrovskaya RU. Impairment of learning and memory after photothrombosis of the prefrontal cortex in rat brain: effects of Noopept. Bull Exp Biol Med. 2002
- Molodavkin GM, Borlikova GG, Voronina TA, Gudasheva TA, Ostrovskaia RU, Tushmalova NA, Seredenin SB. [Effect of the novel dipeptide nootropic agent noopept and its metabolite cyclo-L-prolylglycine on the transcallosal evoked potential in the rat brain]. Eksp Klin Farmakol. 2002
- Romanova GA, Mirzoev TK, Barskov IV, Victorov IV, Gudasheva TA, Ostrovskaya RU. Antiamnesic effect of acyl-prolyl-containing dipeptide (GVS-111) in compression-induced damage to frontal cortex. Bull Exp Biol Med. 2000
Article last updated on: March 13th, 2018 by Nootriment
1 Comment
I’ve found it essential to take choline with any nootropic i’ve tried so far. each of them can give you a headache, and might have a come-down, but choline prevents that, and cures any after-effect of a headache pretty quickly. I am a pescatarian, choline levels might be fine for meat-eaters, but is not present in a lot of plants and fish, so this could be a reason for it being essential, and have taken to having it more regularly.