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Noopept is a nootropic brain booster that is similar to but substantially stronger than Racetams such as Piracetam and Aniracetam.
Noopept powder affects the brain in similar ways to Piracetam by stimulating certain receptors in the brain that are responsible for producing neurotransmitters.
Noopept is a peptide or amide which means it features a combination of amino acids in its chemical structure.
This distinct molecular structure is what makes Noopept so much more powerful than Racetams because it is highly bioavailable.
Noopept effects are associated with increased overall brain power, better ability to learn new ideas, improved concentration, memory boosting, and even reducing the symptoms of anxiety and depression.
There are also no known negative noopept side effects or dangers to be concerned with at the suggested dose.
What follows is a guide to proper Noopept power usage and dosages as well as a closer look at the many noopept benefits.
Mental Energy
Memory
Brain Health- Supports memory, focus & mood
- Boosts mental alertness & energy
- Increases BDNF & promotes brain health
What is Noopept?
Related Topics
- What is Noopept?
- User Reviews
- Reported Benefits
- How it Works
- Negative Side Effects
- Typical Experiences
- Recommended Dosage
- Best Way to Take
- Stacking with Choline
- Recommended Nootropic Stacks
- Purchasing Guide
- Bulk Noopept Powder
- Buy Noopept Capsules
- Is Noopept Legal?
- Comparison to Piracetam
- Comparison to Aniracetam
- Comparison to Oxiracetam
- Comparison to Pramiracetam
Noopept was first created in the 1970s and was patented in Russia and the USA in 1995.
It is an N-acyl-prolyldipeptide and has been trademarked by its manufacturer JSC LEKKO Pharmaceuticals.
While it is not itself a racetam, its mechanism of action is very similar to that of the nootropic Piracetam.
However, Noopept has been researched to be “1000 times stronger than Piracetam” according to an article in the Russian medical journal Experiments in Clinical Pharmacology.
This is because noopept is metabolized by the body as a much faster rate and is better able to cross the blood-brain divide.
As a result, you can take a substantially smaller dosage of noopept to get the same results of a large dosage of piracetam.
- 1000x more potent than Piracetam
- Supports memory, focus and mood
- Boosts mental alertness and energy
How Does Noopept Work?
Noopept stimulates receptors in the brain related to several different neurotransmitters that improve cognitive ability at once. It’s method of action is similar both to racetams as well as ampakines.
Noopept is an AMPA and NMDA glutamate receptor agonist and it also stimulates Acetylcholine neurotransmitter secretions. Higher levels of these two neurochemicals results in better performance in several different areas of cognitive testing such as improved synapse plasticity which is important for learning and memory.
Noopept also activates dopamine and serotonin receptor sites which explains why this nootropic has mood boosting effects as well. People who take Noopept tend to report that it makes them feel more alert, energetic, and generally better able to concentrate.
Evidence suggests that this compound may also increase reflexes, perceptive ability, and improve critical analysis and logical thinking ability.
This peptide nootropic may also be able to treat certain symptoms related to Alzheimer’s and other forms of memory loss.
In trials conducted on rats, taking noopept resulted in higher levels of Nerve Growth Factor – a protein that helps to maintain and repair damaged cells as well as regrow new brain cells. As far as nootropics go, Noopept is one of the most well-rounded offering benefits in many different areas.
- Focus longer, clear brain fog & feel more motivated
- Boost energy, alertnes & memory
- Contains 12 safe and natural nootropic ingredients
Noopept Dosage
The recommended dosage of noopept powder is between 10 and 40 mg at a time.
Because it is such a powerful nootropic supplement, utmost care is necessary when preparing your noopept dosage.
Noopept side effects are minimal at this dosage level and several studies attest to its safety in human use.
In higher quantities, overdoses are possible and may come with negative side effects. Side effects can range from headaches, insomnia, nausea, fatigue, or other forms of digestive discomfort.
Noopept Stacks
Noopept is a powerful nootropic on its own, but you will also see it stacked with other nootropic supplements in a wide range of Noopept Stack dosages. It is not uncommon to stack Noopept with Racetams such as Aniracetam and Piracetam.
You will also see Noopept stacks with Choline supplements like Alpha GPC GPC and CPD Choline which are two stronger versions of the Choline salt. Noopept effects are even stronger when combined with choline because Noopept increases uptake of the neurotransmitter acetylcholine which requires choline to be produced.
You can also combine Noopept with one of the many natural or herbal nootropics available.
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- Bel'nik AP, Ostrovskaya RU, Poletaeva II. Genotype-dependent characteristics of behavior in mice in cognitive tests. The effects of Noopept. Neurosci Behav Physiol. 2009
- Ostrovskaia RU, Liapina LA, Pastorova VE, Mirzoev TKh, Gudasheva TA, Seredenin SB, Ashmarin IP. [Multicomponent antithrombotic effect of the neuroprotective prolyl dipeptide GVS-111 and its major metabolite cyclo-L-prolylglycine]. Eksp Klin Farmakol. 2002
- Kovalenko LP, Smol'nikova NM, Alekseeva SV, Nemova EP, Sorokina AV, Miramedova MG, Kurapova SP, Sidorina EI, Kulakova AV, Daugel'-Dauge NO. [Preclinical study of noopept toxicity]. Eksp Klin Farmakol. 2002
- Ostrovskaya RU, Zolotov NN, Ozerova IV, Ivanova EA, Kapitsa IG, Taraban KV, Michunskaya AM, Voronina TA, Gudasheva TA, Seredenin SB. Noopept normalizes parameters of the incretin system in rats with experimental diabetes. Bull Exp Biol Med. 2014
- Ostrovskaya RU, Mirsoev TK, Romanova GA, Gudasheva TA, Kravchenko EV, Trofimov CC, Voronina TA, Seredenin SB. Proline-containing dipeptide GVS-111 retains nootropic activity after oral administration. Bull Exp Biol Med. 2001
- Molodavkin GM, Borlikova GG, Voronina TA, Gudasheva TA, Ostrovskaia RU, Tushmalova NA, Seredenin SB. [Effect of the novel dipeptide nootropic agent noopept and its metabolite cyclo-L-prolylglycine on the transcallosal evoked potential in the rat brain]. Eksp Klin Farmakol. 2002
- Romanova GA, Shakova FM, Gudasheva TA, Ostrovskaya RU. Impairment of learning and memory after photothrombosis of the prefrontal cortex in rat brain: effects of Noopept. Bull Exp Biol Med. 2002
- Mordyk AV, Lysov AV, Kondria AV, Gol'dzon MA, Khlebova NV. [Prevention of neuro- and cardiotoxic side effects of tuberculosis chemotherapy with noopept]. Klin Med (Mosk). 2009
Article last updated on: March 13th, 2018 by Nootriment
4 Comments
I have struggled with short and not so short memory loss for the past several years..I am in my early 70..it sounds like this may help….what say you?
What is the best time for taking noopept ? Does it matter if it’s on an empty stomach or ? Also, is it okay to take it in the morning and drink alcohol in the evening ?
Hello, thanks for your question!
I generally take noopept about 4 times a day with 2 – 3 hours in between because it has a short half-life. I use it sublingually, but you can take it orally. Some people might experience stomach discomfort if they take it on an empty stomach, in which case you can consume it with food.
Drinking alcohol with noopept could increase the risk of side effects, especially at higher doses. It’s best to avoid combining them.
If I want to mix noopept powder into a liquid is it better to use water or something else?