Noopept powder is often praised as the best nootropic widely available in modern times.
This cognitive enhancement supplement has been tested to significantly improve results on a number of mental performance metrics and even contribute to better brain health.
Over time, Noopept will increase your learning capacity, your intelligent reasoning skills, your memory, concentration, and even perceptual awareness.
It does this by stimulating the excitatory receptors in the brain, thereby contributing to higher levels of cognition and neural activity. But using Noopept alone will only get you halfway there.
Taking a Noopept stack that combines other “smart drugs” and natural nootropic supplements will not only strengthen the benefits, it can also help you increase your brain power with a wider range of mechanisms at once.



- Supports memory, focus & mood
- Boosts mental alertness & energy
- Increases BDNF & promotes brain health
Noopept Stacks
Related Topics
- What is Noopept?
- User Reviews
- Reported Benefits
- How it Works
- Negative Side Effects
- Typical Experiences
- Recommended Dosage
- Best Way to Take
- Stacking with Choline
- Recommended Nootropic Stacks
- Purchasing Guide
- Bulk Noopept Powder
- Buy Noopept Capsules
- Is Noopept Legal?
- Comparison to Piracetam
- Comparison to Aniracetam
- Comparison to Oxiracetam
- Comparison to Pramiracetam
It is interesting to note that the practice of stacking supplements originated with athletes looking to gain extra advantages by synergizing the pathways of several different compounds.
Stacking, for those who might not be familiar with the term, is the practice of taking two or more supplements together in an effort to gain additional benefits or to intensity specific effects.
This practice has now carried over into the world of Nootropics and cognitive enhancers.
By using Noopept with other nootropics, you can actually see improvements above and beyond what you would see if you were using different compounds independently.
Many users might be wondering exactly what to use in a Noopept stack and how to use these nootropic combinations properly.
In this article we will look at some of the best Noopept stacks used today as well as address concerns about potential side effects and whether it might be a good idea to cycle your stack.
Understanding Noopept:
Noopept is one of the most potent Nootropics that has a concentration thousands of times stronger than Piracetam. For this reason there is not a tremendous amount of information available Noopept stacks.
In other words, this powerful substance is not for everyone. Those who have never taken a Nootropic supplement before should start with using Noopept on its own instead of stacking it with other compounds.
In fact, they should probably start with something like Piracetam and maybe Choline as a great stack of beginners.
Once you have some experience with nootropics, Noopept has a number of noteworthy benefits that most nootropics cannot compare to. This peptide nootropic is particularly adept at being able to enhance memory, both short and long-term.
In addition to increased memory, it also may help to improve learning capacity, mental energy, attention span, concentration, and focus.
This supplement is also known to be neuroprotective which means it may be able to help protect the brain from certain types of cellular damage. This could be anything from reducing the damage caused by an excessive amount of alcohol to smoking to other environmental toxins.
There is even substantial research suggesting that Noopept could help in the treatment of a number of degenerative cognitive disorders like Alzheimer’s, schizophrenia, and dementia.

- 1000x more potent than Piracetam
- Supports memory, focus and mood
- Boosts mental alertness and energy
Potential Noopept Stacks:
The first stack that might be beneficial for a number of people is taking Noopept together with Piracetam and Alpha GPC (or other high quality Choline supplements). The theory behind this is that the Piracetam may help to enhance the effects already obtained through Noopept.
The Alpha GPC helps to make the Piracetam work more effectively and can also help to eliminate headaches.
Since Piracetam works on the neurotransmitter Acetylcholine and Noopept primarily affects the neurotransmitter Glutamate, this combination could result in dramatic improvements in cognition, memory formation and the ability to manipulate concepts and perform computations.
Another interesting Noopept stack is to combine it with Huperzine A and another Choline supplement. This will further enhance the acetylcholine activity of Noopept because Huperzine A is an acetylcholinesterase inhibitor.
Huperzine A comes from the Huperzia plant making it one of the most popular natural nootropics available currently. This herbal supplement helps to prevent the breakdown of extra-cellular acetylcholine in the brain so that it remains active in the synaptic cleft for a longer period of time.
The result is greater cholinergic stimulation as well as enhanced pre-synaptic acetylcholine re-uptake so that your brain is able to communicate even more effectively.
When stacking Noopept and Huperzine, make sure not to take more than 50 mcg of Huperzine as this Cholinesterase Inhibitor is very powerful.
Another way enhance the effects of Noopept is by adding nootropics with a mood elevating or enhancing effect. Noopept itself has some anti-anxiety benefits because it stimulates Glutamate which then breaks down into GABA, but these effects can be made significantly stronger in a stack. Combine Noopept together with Aniracetam, CDP Choline, and Sulbutiamine for a great mood boosting stack.
This will provide a great sensation of “relaxed stimulation” with some excellent cognitive benefits along with a feeling of general well-being. This Noopept stack can even be used as a pre-workout combo with the addition of caffeine or L-Theanine.

- Focus longer, clear brain fog & feel more motivated
- Boost energy, alertnes & memory
- Contains 12 safe and natural nootropic ingredients
Designing Your Own Noopept Stack:
While this list of nootropic stacks is a good starting place, there is really no limit to what you can combine with Noopept.
The idea behind a stack is to personalize your nootropic supplements to get exactly the right mix of effects for your needs.
You first want to sit down and think about what specific goals you are trying to accomplish by taking brain boosting drugs and cognitive enhancers.
With Noopept as the base of your stack there are really two main options. First, try and add other Racetams, Ampakines or herbal nootropics things that will strengthen the cognitive benefits. Second, add in unrelated ingredients to produce a wider array of benefits all at the same time.
The first scenario is what most people opt to do. This could be done by picking basically any of the existing Racetams: Aniracetam, Oxiracetam, Piracetam, Pramiracetam, etc… These all work slightly differently so they should be more or less effective at accomplishing the goal.
The second scenario is more tricky. It involves analyzing the specific mechanisms of action by which the various supplements actually work. This means hoping to combine those which will not get in the way of each other or cause reactions with each other (or with other medications that are being used).
In the end, trial and error is the best way to decide what Noopept stack you should be using based on your goals. It can take some people several months of experimentation to create the perfect stack, but when you get it just right the effects are unbelievable.
To Cycle Or Not To Cycle:
You might see a lot of conflicting advice out there on the question of whether to cycle your Noopept Stack.
Noopept has a mid-level of tolerance build-up which means that after a long period of continuous usage you might start to see the effects diminish. If this happens to you, cycling Noopept with other nootropics is an excellent idea.
The idea is that the human body is a wonderfully adaptive organism, therefore adjustments will occur that make whatever supplements are consumed less effective over time. Simply do not give the body time to adjust.
Use the stack for one week, then take five days off. Maybe then come back on for three days and then two more days off. Keep changing things around. This should keep your Noopept stack producing maximal benefits for a long time to come.
- Alekseeva SV, Kovalenko LP, Tallerova AV, Gudasheva TA, Durnev AD. [An experimental study of the anti-inflammatory action of noopept and its effect on the level of cytokines]. Eksp Klin Farmakol. 2012
- Ostrovskaya RU, Ozerova IV, Gudascheva TA, Kapitsa IG, Ivanova EA, Voronina TA, Seredenin SB. Comparative activity of proline-containing dipeptide noopept and inhibitor of dipeptidyl peptidase-4 sitagliptin in a rat model of developing diabetes. Bull Exp Biol Med. 2014
- Andreeva NA, Stel'mashuk EV, Isaev NK, Ostrovskaya RU, Gudasheva TA, Viktorov IV. Neuroprotective properties of nootropic dipeptide GVS-111 in in vitro oxygen-glucose deprivation, glutamate toxicity and oxidative stress. Bull Exp Biol Med. 2000
- Neznamov GG, Teleshova ES. Comparative studies of Noopept and piracetam in the treatment of patients with mild cognitive disorders in organic brain diseases of vascular and traumatic origin. Neurosci Behav Physiol. 2009
- Voronina TA, Guzevatykh LS, Trofimov SS. [Comparative study of the long-term behavioral effects of noopept and piracetam in adult male rats and female rats in postnatal period]. Eksp Klin Farmakol. 2005
- Vorobyov V, Kaptsov V, Kovalev G, Sengpiel F. Effects of nootropics on the EEG in conscious rats and their modification by glutamatergic inhibitors. Brain Res Bull. 2011
- Kondratenko RV, Derevyagin VI, Skrebitsky VG. Novel nootropic dipeptide Noopept increases inhibitory synaptic transmission in CA1 pyramidal cells. Neurosci Lett. 2010
Article last updated on: March 13th, 2018 by Nootriment
6 Comments
Noopept
Alpha GPC
Huperzine A
L-Theamine
Vinpocetine
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Just about to start with my study stack, preparing for interviews. Any suggestions or things to be careful about ?
How did the stack go?
Any recommendations on the Noopept, Alpha GPC, Huperzine A combo?
Are there any safe stacks to combine with Vyvanse, or possibly cycle with it? Not only is Vyvanse expensive, but I feel I lose its effects within 4-6 hours. I’m looking for something cheaper to either add to its efficacy or cycle with.
What I don’t get is if the body is wonderful and can adapt or build tolerances to things. Why the hell doesn’t it adapt and help us all not feel like crap? Do our bodies hate us that much?
There is a typo on this page. “promots”.
Thanks Del :) I will edit this now – my bad.