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When you first start taking nootropic supplements, you will likely begin with a single compound or smart drug at a time.
You may decide to use a Racetam like Piracetam or Noopept, try a natural nootropic like Ginkgo Biloba, or buy a pre-designed product like Alpha Brain or Doxiderol.
All of these options are great for beginners, but nootropics work best when they are mixed with synergistic substances. A nootropic regimen is simply the practice of taking several different nootropics either simultaneously or according to a regular schedule.
Understanding how to stack nootropics to achieve the best results is an important step in designing a personalized cognitive supplementation regimen.
In this article, we will look at how you can pick nootropics for your regimen that will complement each other and actually intensify your benefits.
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Building a Synergistic Nootropic Regimen
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When you take one supplement at a time – such as Piracetam – you inevitably limit the full scope of effects that you can achieve.
A lot of people start out researching nootropics by looking for the single best drug or product to satisfy all of their needs.
If your primary goal is to increase your memory, you might decide on Noopept or Oxiracetam.
If you want to enhance your mood and curb anxiety, you may pick Aniracetam.
If you want to get motivated and boost concentration, then Pramiracetam or Modafinil are good choices.
This is a good start, but one nootropic may only be able to activate a small number of neural pathways. If you were to combine that chemical with other ingredients, you may then be able to take advantage of other mechanisms of action that will actually enhance your original goal.
Alpha GPC and Huperzine: Memory Enhancing Regimen
A perfect example of synergistic effects is the combination of Alpha GPC and Huperzine A – a pair that are found together in many natural nootropic stacks like Alpha Brain. Alpha GPC causes higher levels of the acetylcholine neurotransmitter in your pre-synaptic neuron vesicles.
This is because Alpha GPC is a direct precursor acetylcholine supplement. When acetylcholine is released by one of your neurons into the synaptic cleft, another enzyme called acetylcholinesterase is then responsible for breaking down any leftover quantities of this neurotransmitter.
However, for a lot of individuals or people with Alzheimer’s, acetylcholinesterase needs to be inhibited so that the acetylcholine can actually be taken up again by your neurons to allow for greater cognitive function.
Huperzine does exactly this – preventing the breakdown of acetylcholine which promotes higher levels of this neurotransmitter. Thus, when you stack Alpha GPC with Huperzine A you effectively increase the maximum amount of acetylcholine that your body will allow to be operational in the brain.
Since acetylcholine is one of the critical neurotransmitters for learning, memory and attention, we see that Alpha GPC and Huperzine have synergistic benefits and are able to potentiate each other.
This is the goal that we wish you replicate in all nootropic regimens: an intensification of the positive effects by combining complementary supplements.
Racetam Choline Regimen: Overall Cognitive Booster
Another paradigm nootropic regimen is the stacking of any of the Racetams – Piracetam, Aniracetam, Pramiracetam, Oxiracetam or Phenylpiracetam – with some form of choline source.
You can pick which Racetam to use based on your specific goals or you can combine two or more at the same time to see improvements in several different areas of cognition and intellect at once.
Racetams work by stimulating the cholinergic system, causing more acetylcholine to be released and causing the formation of new synapses between neurons.
However, Racetams can only be fully effective if there is sufficient acetylcholine to keep up with demand. In fact, in some cases if you do not have enough choline in your diet, you may experience a “Piracetam Headache” in which over-stimulation of cholinergic neurons results in pain in the head.
There are synergistic benefits to using a choline supplement in your Racetam nootropic regimen. Not only does this have the potential to cure headaches, but it can also intensify the intellectual and memory-boosting gains seen with taking a Racetam on its own.
You will have several different choices for which Choline supplement to use in your regimen, but the three best regarded ones are Alpha GPC, CDP Choline and Centrophenoxine.
When using a Racetam Choline Stack, you may notice an even more acute improvement in concentration, mental clarity and comprehension of abstract concepts. You might find that your memory recall is more vivid and that you do not have to work as hard to remember small details from your daily activities or studies.
For the best results, you should be taking some type of Choline additive with every administration of your Racetams.
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Caffeine and Theanine Regimen: Stimulation without Anxiousness
Another excellent supplement regimen that shows cognitive synergies is taking caffeine together with Theanine. Caffeine actually falls into the category of a psychoactive drug and is not a nootropic per se, but convention has resulted in it frequently being lumped in with other “smart pills”.
This combination occurs naturally in Green Tea which is why it is favored by a lot of individuals who prefer to only use herbal supplements.
While caffeine is great for giving you energy and raising alertness, sometimes taking this drug results in restlessness and anxiety. This can actually take away from your mental productivity as energy is diverted to the natural bodily stress reaction.
Theanine can actually limit these negative side effects by producing a sensation of relaxation and calm. Theanine has been found to possess anxiolytic characteristic, capable of inhibiting the stress response that is associated with caffeine. T
he result is that many users find they experience a more focused sense of stimulation when using these nootropics together. While you would need about 10 cups of Green Tea to achieve recommended dosages of these supplements, you can buy these ingredients at reasonable prices online.
Typically a two to one ratio of theanine to caffeine will give you the best results.
What Nootropic Regimen Should You Use?
There are an estimated 150 different supplements out there that have nootropic characteristics, so how exactly are you supposed to decide what should go into your regimen?
The best advice is to start with the basics and add from there once you learn more about the many diverse compounds available.
Some nootropics regimens can include a dozen or more different substances that are either taken together every single day or cycled according to a pre-set schedule.
For example, Noopept and Pramiracetam are two of the strongest nootropics, but you can build up a tolerance to them with too much usage. One option would be to just cycle these substances on days when you know that you need to engage in extended mental exertion.
You may only want to use these compounds every Tuesday and Thursday while taking Piracetam or Aniracetam the rest of the week depending on your personal schedule.
There are some natural nootropics that are widely agreed to be always a worthwhile addition to your stack such as Huperzine, Vinpocetine, Fish Oil, Bacopa, Vitamin B6 and L-Tyrosine.
You can add these to your regimen simply by purchasing one of the several stack products out there. This will save you from hunting down each of these supplements on their own.
Then, the best advice is to experiment and make sure you are recording changes in your experience or using a brain training system to track your progress. It is truly an incredible feeling when you discover just the right combination of nootropics to optimize your brain.
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Article last updated on: February 10th, 2018 by Nootriment