Nootropic supplements can provide serious mood enhancing effects for anyone who needs a boost. Whether you are feeling temporarily low in energy or are experiencing symptoms of depression, nootropics may help.
If these symptoms persist it is a good idea to see your doctor, but in the short term nootropics can address certain chemical imbalances.
Some nootropics can improve imbalances in the brain such as low serotonin or dopamine levels. Other nootropics work by stimulating your central nervous system or by simply increasing blood flow and oxygenation of the brain, leading to increased motivation and energy levels.
Here is a list of the Best Nootropics for Mood Enhancement as well as some information on how these supplements work.



- Promotes brain health & communication
- Supports memory, reasoning & cognition
- oosts focus, mental clarity & attention
The Best Nootropic Mood Boosters:
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- Nootropics List
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- Effects & Benefits
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- Natural Nootropics
- Enhace Intelligence
- Boost Memory
- Improve Concentration
- Reduce Anxiety
- Treat Depression
- Nootropic Side Effects & Dangers
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1. Aniracetam
Aniracetam is one of the classic nootropics that falsl into the Racetam category. Initially designed as a more powerful alternative to Piracetam, it was discovered that Aniracetam is also an effective mood booster.
There are several ways that Aniracetam powder can help you overcome depression, social anxiety and other related afflictions.
Aniracetam stimulates the AMPA receptors in your brain causing increased Glutamate uptake and more mental energy. This is why Aniracetam is often used as a concentration and studying aid, but it can also be used to overcome some of the “ennui” and fatigue associated with depression.
Aniracetam also causes higher levels of acetylcholine in the brain, making it easier for the different areas of your brain to communicate. This can improve verbal processing and communication skills so that you are more at ease when participating in social activities.
Aniracetam also has been documented to increase feelings of general well-being with continued long-term use.
Some Aniracetam reviews report that this supplement helps make them feel relaxed and at ease – an effect which is attributed to increased release of dopamine and serotonin. Taking Aniracetam as an anxiolytic is also associated with very few side effects and is generally regarded as very safe.
2. Noopept
If you have given Aniracetam a try and are looking for something more concentrated, then Noopept is the next option.
Noopept is believed to be over 200 times higher in potency than Aniracetam. Noopept is a peptide Piracetam derivative and operates in similar ways to this nootropic compound.
One benefit of Noopept vs Aniracetam is that the effects are observed for longer periods of time: While Aniracetam can wear off within 2-3 hours, Noopept will last up to 5-6 hours.
Noopept is also known to increase the amount of serotonin and dopamine in the brain – the two most important mood enhancing chemicals. Noopept is considered to be a potent anxiolytic and an excellent nootropic for motivation, focus, attention span and increased energy. Some people will stack Aniracetam and Noopept together to amplify their effectiveness.

- Focus longer, clear brain fog & feel more motivated
- Boost energy, alertnes & memory
- Contains 12 safe and natural nootropic ingredients
3. Sulbitiamine
Sulbutiamine powder is a stronger synthetic form of Vitamin B1 (Thiamine) that improves memory, cognition, energy and mood. It was designed to be more efficient at crossing the blood-brain barrier, resulting in higher levels of Thiamine in the brain.
Like Aniracetam and Noopept, Sulbutiamine influences acetylcholine and glutamine release, but it also can directly influence the amount of dopamine in the brain.
Using Sulbutiamine increases D1 dopamine receptor concentration in the area of your brain known as the prefontal cortex. This is what makes it such an effective nootropic for mood enhancement. Taking Sulbutiamine supplements to relieve stress and anxiety has also become common among recreational users.
4. Inositol
Inositol works similarly to Sulbutiamine and other B vitamin nootropics. (It sometimes even goes by the name Vitamin B8.) Inositol is a naturally derived nootropic that actually was first discovered in human spinal fluid.
Some depression sufferers are found to have lower levels of Inositol in their spinal fluid which is why supplementation may be necessary. It can alleviate symptoms of depression, anxiety, panic attacks, stress and insomnia.
Even if you are not experiencing serious signs of depression, using Inositol can help generally improve your mood and reduce temporary negative thoughts.
5. Adrafinil
Adrafinil is a legal source of Modafinil – one of the best stimulants for nootropic mood enhancement. Modafinil is a prescription drug in the USA that is prescribed for alertness and wakefulness in patients with abnormal fatigue.
Because Modafinil is hard to acquire, many nootropic users have turned to buying Adrafinil powder online which converts into the drug Modafinil in the liver, resulting in very high amounts of energy and motivation.
It is a favorite of businessmen and businesswomen in highly competitive industries who need to make sure they are always at peak performance. However, this compound is much stronger than the other nootropics listed here and can cause negative side effects with excessive usage.
Only use Adrafinil on rare occasions and after seeking advice from a medical practitioner.
Article last updated on: July 3rd, 2018 by Nootriment