Before you start using Nootropics, you might be wondering about exactly what happens when you terminate your usage of one of these brain-boosting supplements, whether it be Piracetam, Noopept, Alpha GPC or otherwise.
While there is no one simple answer for all of the compounds which are considered types of Nootropics, there are some common experiences that hold true most of the time.
Nootropics are considered very safe, non-addictive and in some cases offer long-term benefits to your brain health even after discontinuing use.
The same cannot be said for certain “Smart Drugs” – especially those that use ingredients that are central nervous system stimulants.
When you stop using Nootropic supplements, you might have a sensation of “brain fog” for a few days as you get used to the perceptual differences, but there are no known physical symptoms of withdrawal.



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Nootropics Withdrawal: Will your Cognitive Abilities Decline?
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One question we have asked to us on Twitter and Facebook regularly is variations of “Will I feel dumber after I stop taking my nootropic dosage?”
A lot of people are concerned that nootropics will just give them a short-term boost and subsequently cause them to feel like they have actually declined in their cognitive capacity.
This is a very legitimate concern because you do not want to become reliant on a supplement of any kind, even if it is non-toxic to the body like the best nootropics are.
Consider that for most people who are unfamiliar with nootropics, the best example they have of a “smart pill” is NZT-48 from the movie Limitless.
While the Limitless drug is not real, we see that anyone who stops taking this drug immediately reverts back to their previous state and seems to have diminished mental capabilities without it.
Fortunately, we know that this is not the case with nootropics – especially those in Racetam family. When you start taking nootropics – such as Piracetam – you will feel greater mental clarity, increased energy and in general find yourself experiencing less “brain strain” as a variety of basic cognitive tasks suddenly become easier.
If you then stop using Piracetam powder on a daily basis, you might feel that mental strain come back and start to wonder if it was caused by ceasing to use this substance.
It is true that when you stop taking Piracetam you will also stop experiencing most of the short-term benefits of this nootropic and it may take you a few days to get used to the difference of being “normal” again.
But you should not worry and think that you have somehow regressed backwards from before you started taking nootropics like Piracetam, Aniractam, Oxiracetam or Noopept.

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We know this because using nootropics like the ones listed above does not cause any sort of tolerance or physical addiction to be formed whereby your neurons now rely on the presence of these drugs in order to perform normally.
There are zero physical signs of withdrawal, unlike so many of the substances that we consume these days. However, you can experience was is called a “mental addiction” where you feel like you need to use nootropics in order to get the best results from your brain.
Think of it like the first time you used Red Bull, Monster or some other form of caffeinated energy drink to help you stay up late and study for an exam. The immediate efficacy of these supplements might make you feel like you need to use them to experience peak brain performance.
In the same way, you may start to miss the benefits of cognitive enhancers causing yourself to feel like you need to continue using them.
How to Retain Nootropic Long-Term Benefits
Is there any way to retain the benefits of nootropics for the long term even after you stop taking them? In fact, some nootropics do provide a degree of long term effects and there are ways that you can further enhance these positive effects.
While many nootropics work in the short-term simply by temporarily raising neurotransmitter levels or by non-permanently modulating neuron receptors, there are also less transient effects that are observable. For example, some nootropics like Lion’s Mane, Acetyl L-Carnitine, and Uridine can increase Nerve Growth Factor which controls the development of new neurons and neurites.
Most Racetams also contribute to maintenance of healthy brains cells, preventing them from damage from oxidative stress and numerous toxins. If your brain develops new neurons and protects existing neurons while using Piracetam or some other nootropic, then that benefit will persist even after you stop taking Piracetam.
In other words, those neurons will not suddenly die just because you stop using your supplement. Any increase to brainpower, memory, learning, perception or neuromuscular control will remain beyond your termination of this nootropic regimen.
Another way in which you can deepen the long-term effectiveness of your nootropics is by engaging in challenging and stimulating activities while using these compounds.
When you take Piracetam, you increase your synaptic plasticity and general computational power. If you exercise that power while using a nootropic, you will conceivably grow your cognitive capacity faster than you would without a supplement that improves neuroplasticity.
Nootropics like Noopept, Aniracetam and Oxiracetam actually cause your brain to form new connections between neurons. These connections are called synapses and your brain’s ability to create new synapse sites on neurons is an important measure of intelligence.
If you challenge your brain with new learning and reasoning tasks while taking Nootropics, your brain will need to form even more of these new synapses which will once again continue to function even after you stop taking Nootropics.
Article last updated on: February 10th, 2018 by Nootriment