Stacking Oxiracetam with other nootropics can provide a potent synergistic effect for the user. In a stack, the benefits are amplified as opposed to being simply additive which means you reap greater results often at smaller dosages.
In order to plan out your nootropic stack, it is important to know kind of specific effects one can expect from the various combinations of smart drugs.
The Oxiracetam Choline stack is a good choice for both novice and experienced nootropic users. The combined benefit of these two nootropic substances is optimal for tasks requiring enhanced cognitive function with a slight psycho-stimulant effect. The Oxiracetam Choline stack is a solid foundation stack with a proven record spanning several decades.
Those new to nootropics do best to select a foundation stack consisting of a couple components which work well for them, and then to add, subtract and cycle them with other smart drugs, over time.
By building slowly, you are able to gauge the effectiveness of each individual component as it mixes with your own body chemistry and with the stack components you are already taking. Building a stack slowly allows you to assess the effect or non-effect each smart drug has on your cognitive abilities, allowing you to fine-tune your doses for optimal performance based on your own neurochemistry.



- Heightens focus, alertness & perception
- Promotes analytical thinking & memory
- Boosts energy & reduces mental fatigue
Oxiracetam
Related Topics
- What is Oxiracetam?
- Dosage Guide
- Reviews
- Oxiracetam Effects
- Side Effects & Safety
- Experience Reports
- Where to Purchase
- Is Oxiracetam Legal?
- Best Oxiracetam Stacks
- Using Oxiracetam Capsules
- Oxiracetam Choline Stack
- Oxiracetam Piracetam Stack
- Aniracetam Oxiracetam Stack
- Pramiracetam Comparison
- Noopept Comparison
- Aniracetam Comparison
The racetam family of smart drugs is the most frequently used throughout the world.
There is both formal research and anecdotal research readily available to potential users showing them to be largely non-toxic and safe to use, and also demonstrating the potential benefits a user can expect.
Their popularity has grown since the 1970s and with the advent of global internet connections and online forums through which users can share information, their popularity continues to increase.
Oxiracetam is more potent than Piracetam, which means it offers improved cognitive performance at lower doses than Piracetam.
This doesn’t mean the cognitive benefits are exceedingly greater, but instead, it means that a much lower dose is required in order to gain the desired effect. Oxiracetam has some benefits which Piracetam doesn’t offer, which sets it apart.
Oxiracetam is a pure nootropic drug. This means it works solely on cognitive function and does not work on the brain chemicals serotonin or dopamine. Oxiracetam is considered an ampakine which offers a slight psycho-stimulant effect in most users.
With this racetam, the user can experience increased memory function, particularly in long term memory and recall, learning ability becomes enhanced and skills related to critical and analytical reasoning are noticeably improved. Some people report an increase in motivation which may be due to the subtle stimulant effect of Oxiracetam.



- Supports memory and synaptic plasticity
- Raises acetylcholine levels
- Promotes brain health and focus
Choline
Choline is the precursor to the neurotransmitter, Acetylcholine. This neurotransmitter plays a vital role in memory formation and consolidation.
Most of the Choline our bodies require comes from common food products like eggs, broccoli and soy, however, a surprising number of people are deficient in this essential nutrient. Supplementing Choline can improve cognitive function including memory and mood.
Choline is used so frequently in combination with racetam stacking because it is thought racetams cause the brain to use acetylcholine at a faster rate. This increased acetylcholine activity can result in headaches for people whose diets do not provide them with adequate Choline. Supplementing with a quality form of Choline like Alpha-GPC or Citicoline will often remedy this side effect.
Oxiracetam Choline Stack Dosage
Using Oxiracetam with a choline source is a natural fit: Oxiracetam is known to stimulate Cholinergic activity while choline ensures there is enough of the acetylcholine neurotransmitter to keep up with the faster firing rate of your neurons.
When stacking two or more nootropic substances together, the effects are almost always potentiated by each other. Because of this, you may need a smaller dose of Oxiracetam when combining it with Choline.
We recommend dosing 800mg Oxiracetam combined with 250mg Citicoline twice each day. Note that you can purchase plain Choline Bitartrate supplements, but this is not recommended as these products are 60% tartaric acid and only 40% choline.
Citicoline and Alpha GPC are much higher quality Choline supplements because they imitate two of the natural forms of choline that occur within the human body. They also achieve a higher rate of absorption in the brain tissue and conversion into acetylcholine.
Oxiracetam Centrophenoxine Stack
Centrophenoxine (Lucidril, Meclofenoxate) is an alternative to choline that can be used to achieve similar benefits. It is a nootropic drug derived from DMAE (Dimethylaminoethanol), which is structurally similar to choline, but has one less methyl group in its chemical structure.
Centrophenoxine has been used in the treatment of senile dementia and Alzheimer’s disease. It demonstrates benefits for cognitive function, memory, neuron health and was even found to increase lifespan in aging mice.
In a stack with Oxiracetam, Centrophenoxine can promote greater cholinergic activity by increasing the synthesis of the neurotransmitter acetylcholine. It is a highly bioavailable pro-drug for DMAE that crosses the blood-brain barrier and which the body can then convert into choline.
This cognitive enhancer has also been shown to reduce the build-up of lipofuscin and other waste products in neurons that can contribute to premature aging. It exhibits a neuroprotectant effect and has been shown to enhance cognitive skins in elderly patients when taken for 8 weeks.
If you are interested in using nootropics for their anti-aging properties, this stack may be a good option for you. An Oxiracetam Centrophenoxine Stack is typically used at a dosage of 750 mg Oxiracetam to 250mg Centrophenoxine.
Centrophenoxine is generally well tolerated and does not have a significant risk of serious side effects. However, women who are pregnant or who may become pregnant should not use this nootropic agent as DMAE can cause teratogenic effects (birth defects) in developing fetuses.

- Focus longer, clear brain fog & feel more motivated
- Boost energy, alertnes & memory
- Contains 12 safe and natural nootropic ingredients
Best Way to Take Oxiracetam
Because of Oxiracetam’s psycho-stimulant effect, it is probably best not to take Oxiracetam late in the day unless you intend to work or study into the night. Keep in mind that most users do not experience the effects of most racetams immediately.
It can take 3-6 weeks before you experience the full effects and it is important to allow for this time to elapse before increasing or adjusting your dose.
If you do experience headache, adjust your Citicoline upward by 100mg per dose, but do not exceed a maximum of 500mg. After a period of 6 weeks, Oxiracetam may be adjusted slowly upward in 100mg increases each week. Do not exceed a maximum of 1500mg per dose.
Some users report this stack is especially useful for tasks requiring linear thinking ability, like math. Logical reasoning ability is often improved and tasks which require intense focus or dense memorization are well-served by this stack. There is some indication that Oxiracetam can result in tolerance if taken continuously, so cycling your stack with other racetams is recommended.
Review
Oxiracetam and Choline work together to provide the user with a potent and popular nootropic stack. Studies have found that combining Racetams with a choline source can produce results three times greater on memory tasks than if you were to administer one of these supplements at a time.
This makes it prudent to combine multiple nootropics both to optimize your experience when taking these compounds as well as to maximize your return on investment by requiring smaller dosages.
This stack can be used by itself, or it can be a foundation from which to build a more varied stack. The Oxiracetam Choline stack is best designed using one of the better choline supplements such as Alpha GPC or Citicoline (CDP Choline).
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Article last updated on: March 14th, 2018 by Nootriment