Are you looking for good nootropic supplements to stack with Oxiracetam?
When you combine multiple brain boosters together, you can attain a higher degree of cognitive enhancement and affect positive changes to different areas of mental function at once.
Among all of the Racetams, Oxiracetam is the one that has the most targeted mechanism of action with a purely cognitive range of effects.
While other Racetams like Piracetam or Aniracetam also pose benefits for mood enhancement and reducing anxiety, Oxiracetam’s effects are specifically focused on improving intellect, memory, mental energy and focus.
For this reason, it is often used as an awesome study pill by students at exam time.
But what can you stack with Oxiracetam to make it even more powerful and to produce greater beneficial effects? Let’s take a look at some of the most popular Oxiracetam stacks used today.



- Heightens focus, alertness & perception
- Promotes analytical thinking & memory
- Boosts energy & reduces mental fatigue
How to Pick an Oxiracetam Stack
Related Topics
- What is Oxiracetam?
- Dosage Guide
- Reviews
- Oxiracetam Effects
- Side Effects & Safety
- Experience Reports
- Where to Purchase
- Is Oxiracetam Legal?
- Best Oxiracetam Stacks
- Using Oxiracetam Capsules
- Oxiracetam Choline Stack
- Oxiracetam Piracetam Stack
- Aniracetam Oxiracetam Stack
- Pramiracetam Comparison
- Noopept Comparison
- Aniracetam Comparison
It is quite likely that you already know a thing or two about the general benefits supplied by Oxiracetam powder.
The first decision to make is whether or not you want to try and intensify these already existing benefits (assuming you are already a regular Oxiracetam user) or if you would like to add some additional benefits to your experience.
Maybe you really like the cognitive boosting benefits of Oxiracetam and would simply like more of the sane. In that case think, about including a nootropic with similar effects but a bit more power (Pramiracetam comes to mind) or a supplement that further enhances these effects of Oxiracetam.
On the other hand, if you wish to expand the effectiveness of your nootropic stack, you may want to pick compounds that work in different ways from Oxiracetam. In this case, consider something like Aniracetam or even Sulbutiamine.
There really are no wrong answers when it comes to designing a nootropic stack and you should let experience be your guide.

- Heightens focus, alertness and perception
- Promotes better analytical thinking and memory
- Boosts energy and reduces mental fatigue
Oxiracetam Choline Stack
The most basic stack you might want to try first is Oxiracetam and choline. Choline is a nutrient in our food that is a precursor to the neurotransmitter acetylcholine.
Oxiracetam works in part by increasing the transmission of this neurotransmitter, resulting in better memory and learning. In order to get the best results from Oxiracetam, you have to make sure that you have higher acetylcholine levels than the average person.
By stacking Oxiracetam with choline you can ensure that there is enough acetylcholine stored in your neurons to keep up with the increased demands of this Racetam. In some cases, not using Oxiracetam with a sufficient choline source can lead to unpleasant headaches because your synapses are being depleted.
There are a few different options for acetylcholine supplements that you can use, but Alpha GPC, Citicoline and Centrophenoxine are three of the best. These are all efficient and highly bioavailable supplements that lead to higher levels of acetylcholine than if you were to take phosphatidylcholine or a choline salt pill.
Furthermore, Alpha GPC, Citicoline and Centrophenoxine are all considered nootropics on their own and may amplify the improvements to your memory formation and cognitive processing.
Oxiracteam Modafinil Stack
If you are in need of some serious studying motivation or need to get seriously productive at work, using Oxiracetam with Modafinil can be highly effective.
Modafinil is a wakefulness agent and alertness promoter that is traditionally prescribed to improve cognitive function for people who are sleep deprived. But it has a number of off-label uses as well including as an energy booster and intense focus aid.
Combining the mental energy, drive and clarity of Modafinil with the brainpower augmentation of Oxiracetam is truly a powerful mix for students and businesspeople in competitive industries.
Another option is to stack with Adrafinil if you are unable to buy Modafinil in your country.
Oxiracteam Piracetam and Aniracetam Stack
Staying within the Racetam family, you may want to try a stack of Oxiracetam, Aniracetam, and Piracetam. While each of these offers similar cognitive benefits, they have slightly different pathways, levels of potency and different half-lives.
When you use multiple Racetams together, you ensure that your neural receptors cannot form a tolerance to any single one which can keep them sensitized to transmissions from neighboring neurons for longer periods of time. Additionally, Aniracetam adds an anti-anxiety benefit that can be helpful to those who are also looking to reduce stress or who are battling sleep problems.
The result is dramatically improved cognition, memory formation, reasoning and fluid intelligence while preserving a sense of calm and positive thoughts.

- Focus longer, clear brain fog & feel more motivated
- Boost energy, alertnes & memory
- Contains 12 safe and natural nootropic ingredients
Oxiracetam Sulbutiamine Stack
Another anxiolytic Oxiracetam stack involved combining this supplement with Sulbutiamine. As a member of the B vitamin family, Sulbutiamine has some great cognition boosting properties in its own right, but it is predominantly thought of as a mood booster and relaxant.
This stack would be good for daily use as a studying aid while you might prefer the more stimulating Modafinil for crunch time.
In general, the hippocampus is believed to be more effective at memory formation during low stress periods of activity, so you may want to try this combination when you are reading long articles or complicated textbooks.
Making Your Own Oxiracetam Stacks:
If none of the above Oxiracetam stacks appeal to you, do not worry.
There is a whole world out there of Nootropics and similar supplements that you can try.
You can use one of the stack above as a starting point or take an entirely different route depending on your goals.
For example, here are just some of the nootropics that are frequently used together with Oxiracetam and the related Racetams:
- Huperzine A – Effective memory booster that synergizes well with Racetams
- Vinpocetine – Increases blood flow to the brain to heighten energy and alertness
- Bacopa – A natural cognitive enhancer that will produce greater gains in memory
- Pyritinol – An analog in Vitamin B6 that optimizes many neural processes
- Inositol – Another member of the B vitamin family which can help with both mood and improve cognition
These supplements are all safe and non-toxic. As with the Nootropics, they are also all generally very well-tolerated and should be able to be easily combined with Oxiracetam and even other Nootropics.
This should offer a lot of room for experimentation and finding the perfect stack and combination to help you achieve your desired results.
You may find that it will take you a few missteps to design the absolutely perfect Oxiracetam stack for yourself, but by continuing to read reviews and user experiences you can learn more about the many options out there today.
- Hlinák Z, Krejcà I. Oxiracetam prevents the MK-801 induced amnesia for the elevated plus-maze in mice. Behav Brain Res. 2000
- Mochizuki D, Sugiyama S, Shinoda Y. [Biochemical studies of oxiracetam (CT-848) on cholinergic neurons]. Nihon Yakurigaku Zasshi. 1992
- Ammassari-Teule M, D'Amato FR, Sansone M, Oliverio A. Enhancement of radial maze performances in CD1 mice after prenatal exposure to oxiracetam: possible role of sustained investigative responses developed during ontogeny. Physiol Behav. 1988
- Spignoli G, Pepeu G. Interactions between oxiracetam, aniracetam and scopolamine on behavior and brain acetylcholine. Pharmacol Biochem Behav. 1987
- Paoli F, Spignoli G, Pepeu G. Oxiracetam and D-pyroglutamic acid antagonize a disruption of passive avoidance behaviour induced by the N-methyl-D-aspartate receptor antagonist 2-amino-5-phosphonovalerate. Psychopharmacology (Berl). 1990
- Moglia A, Sinforiani E, Zandrini C, Gualtieri S, Corsico R, Arrigo A. Activity of oxiracetam in patients with organic brain syndrome: a neuropsychological study. Clin Neuropharmacol. 1986
- Green RC, Goldstein FC, Auchus AP, Presley R, Clark WS, Van Tuyl L, Green J, Hersch SM, Karp HR. Treatment trial of oxiracetam in Alzheimer's disease. Arch Neurol. 1992
- Belfiore P, Ponzio F, Biagetti R, Berettera C, Magnani M, Pozzi O. Oxiracetam prevents the hippocampal cholinergic hypofunction induced by the NMDA receptor blocker AP7. Neurosci Lett. 1992
Article last updated on: March 13th, 2018 by Nootriment
2 Comments
good insights
Careful throwing around things like “these supplements are all safe and non-toxic”. Bacopa can be very toxic to the liver