Phenibut 500 mg supplements are renowned for their ability to improve the mood, promote sociability, and help people fall asleep.
You can buy name-brand Phenibut 500 mg tablets from sources like Serious Nutrition Supplements, or as less expensive generic formulations.
Phenibut (also known as Noofen or Fenibut) is a derivative of a naturally occurring neurotransmitter known as GABA. GABA has a targeted inhibitory effect upon the brain, placing a limiting factor on neural circuits that can lead to anxiety or social phobias.
Phenibut is structurally similar to GABA with the addition of a Phenyl group, which makes it more stable and able to enter into the central nervous system. GABA produced in the body to be used in the brain is made in the central nervous system, because GABA is not able to any great degree to cross the protective membrane separating the bloodstream from the brain (blood-brain barrier).
As such, anyone currently taking GABA supplements may see much better results with even a 500 mg dosage of Phenibut.



- Powerful anxiolytic for stress reduction
- Stimulates GABA receptors & supports sleep
- Neuroprotective & supports cognitive function
Why Take Phenibut 500mg?
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Phenibut is sold as a nutritional substance in the United Stated and is used by individuals for social anxiety as well as generally supporting relaxation and feelings of well-being.
In Russia, it is used as a psychotropic drug and is one of the most common treatments for General Anxiety Disorders. Russian studies also report that Phenibut has a number of Nootropic actions and effects, improving the way your brain functions.
Studies have observed that Phenibut may improve intellectual capacities like acuity, reasoning, memory, awareness, and concentration. Phenibut may also be capable of inducing calmness and tranquility without depressing the central nervous system or leading to fatigue.
Since its discovery in the 1960’s, in Russia, Phenibut has been used to treat a wide variety of ailments including post-traumatic stress disorder, anxiety, depression, and insomnia.
Users looking for Phenibut 500 mg pills are typically taking it for reducing anxiety, increasing social behavior, and preventing panic attacks or other mental inhibitions that can make day to day activities difficult. The primary anxiolytic effects of Phenibut are believed to be to due to increasing circulating GABA in the brain.
As the chief inhibitory neurotransmitter, GABA helps to shut down overactive neurons that are firing too quickly. It can prevent excitotoxicity due to glutamate and other excitatory neurotransmitters, while actually facilitating better communication between normally functioning neurons.
Anxiety is thought to result from an inability to shut down communication between certain neural systems, resulting in obsessions or fixations particularly of a negative nature. This can result in irrational fears or inhibitions, especially as they relate to novel social settings.
Using Phenibut may improve the regulation of these neural circuits, lessening anxious thoughts with fewer side effects than typical anti-anxiety medications. There are many users who report being able to overcome their social anxiety as a result of supplementation with 500 mg Phenibut capsules.

- Powerful anxiolytic for stress reduction
- Improves sleep and may reduce insomnia
- Neuroprotective and cardioprotective effects
Another benefit of Phenibut is improved sleep quality. For people who have a difficult time falling asleep in the first place or sleeping restfully all night long, this supplement may be a game-changer. Many users report falling asleep faster, staying asleep, and waking up feeling much more refreshed. As well, some users even take Phenibut supplements recreationally to promote lucid dreaming.
It is believed that this supplement also has neuroprotective qualities, and may be able to prevent some of the neuronal damage caused by high stress levels. It may also help to lessen the pressure on the ventricles of your heart, making Phenibut cardioprotective when used properly.
A lesser known reason to take Phenibut 500 mg supplements is to enhance cognitive functioning. Phenibut is a nootropic which means that it can improve the way your brain works, potentially contributing to better fluid intelligence and cerebral productivity.
It has been known to improve memory retention and synaptic plasticity, as well as learning ability in some users, but this is not true for everyone. One of the other key cognitive benefits is the ability to improve communication between the two hemispheres of the brain.
Phenibut can enhance problem solving skills as well as helping you to develop more creative thought and better associative reasoning skills. To the extent that it can prevent distractions, it may also lengthen attention span and the ability to concentrate and focus.
The nootropic properties of Phenibut should really be seen as a bonus instead of the primary effect of this supplement. This compound works best when used for mood enhancement or reducing anxious thoughts. What makes it unique compared to many other anxiety treatments is that it may alleviate these feelings without impairing cognitive function.
However, if you specifically want to experiment with cognitive enhancers, there are much better choices out there like the Racetams (Piracetam, Aniracetam, Oxiracetam and Pramiracetam). Aniracetam in particular is known to reduce feelings of anxiety while significantly improving brain function.
It is quite common for Phenibut users to take this nootropic only when experiencing anxiety and to use Aniracetam on a more regular basis as a preventative tool.

- Most effective supplements to improve mood
- Optimize levels of dopamine, serotonin and GABA
- Protect against stress and anxiety
Using Phenibut 500mg
How you use your Phenibut 500 mg capsules will be dependent on your main reasons for taking it. If you decide to use this supplement daily for anxiety, you may want to split the dosage into two to three administrations per day.
Others will take it only on an as-needed basis when they are experiencing anxious thoughts or in preparation for social gatherings. Still others will use it only at night as a sleep aid.
The recommended daily dosage range is between 250 and 1,000 mg with some individuals taking as much as 2,000 mg per day (not recommended). New users are advised to begin with a low dose (ideally as low as possible). You only want to increase once you have become familiar with all of the effects caused by Phenibut.
Since Phenibut is water-soluble it does not need to be taken with food or meals. You generally will only need to take it once or twice a day since the half-life is between 5 and 6 hours. If you continue to use it on a regular basis, you may develop a tolerance such that 500 mg of Phenibut no longer provides you the same effects.
Instead of increasing your dosage, it is recommended to cycle off the supplement every two weeks so that your body is given time to adjust.
Recently, some of the larger brands that sell Phenibut 500 mg tablets have stopped carrying this supplement and instead only sell it in powder format. This allows them to keep the cost as low as possible for the consumer. The powder can be mixed with water or juice, but it does tend to have a very bitter taste, so some may prefer putting it into capsules.
Phenibut Side Effects
Even at 500 mg, Phenibut is a very powerful nootropic and anxiolytic. Serious and dangerous side effects can occur if it is used improperly. The best advice regarding the side effects of Phenibut is to make sure to never exceed the recommended dosage range.
Higher doses for long periods of time tend to lead to side effects including fatigue, nausea, light headedness, headaches, stomach issues, and potentially memory loss and loss of consciousness in extreme cases with excessive dosages. It should also not be used in conjunction with alcohol or other drugs.
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Article last updated on: March 13th, 2018 by Nootriment