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Phenibut powder or crystals is the most economical way of purchasing this nootropic supplement that is most commonly used for anxiety.
This supplement is frequently taken by individuals who experience social anxiety, high levels of stress and difficulty falling asleep.
Phenibut is used to promote relaxation, improve mood, and make it easier to fall asleep. Some research studies have even found it may have a positive effect on concentration and mental abilities.
Some companies like Primaforce and SNS sell pure Phenibut capsules, but these brand name products are almost always more expensive than generic Phenibut powder. By purchasing powdered Phenibut in bulk, you may reduce your cost per dosage by 50% or more while also achieving greater control over your dosages.
Anxiety
Mood
Sleep & Insomnia- Powerful anxiolytic for stress reduction
- Stimulates GABA receptors & supports sleep
- Neuroprotective & supports cognitive function
Overview of Phenibut Powder
Related Topics
- What is Phenibut?
- User Review
- Benefits and Uses
- Dosage Recommendations
- Effects & Mechanisms of Action
- Experience Reports
- Anti-Anxiety Effects
- Using Phenibut for Sleep
- How to Take
- Negative Side Effects
- Withdrawal Dangers
- Risks with Alcohol Combination
- Comparison to Picamilon
- Buying Phenibut Guide
- Using Bulk Powder
- Primaforce Phenibut Review
- SNS Phenibut XT Review
Phenibut is a nutritional supplement developed in what is now Russia during the 1960’s.
It has been actively used in Russia and Eastern Europe since this time, but given its appearance during the Cold War it is not surprising that many in the US have not yet heard about it.
Recently, it has become popular in the Western world as an alternative to Valium with a much better tolerability profile for most users.
Phenibut (also known as Noofen or Fenibut) is a synthetic derivative of GABA which is a neurotransmitter that is primarily inhibitory in nature. If you look at the Phenibut chemical structure, it is essentially a GABA molecule with a Phenyl molecular ring attached to it.
GABA on its own cannot cross over the blood-brain barrier to any great degree when you ingest it as a supplement. The addition of the Phenyl ring, works as a delivery system which allows the compound to cross over from the blood stream and interact directly with neurons in the brain.
The result is higher levels of GABA activity in the brain and better regulation of over-excitement and anxiety.
- Powerful anxiolytic for stress reduction
- Improves sleep and may reduce insomnia
- Neuroprotective and cardioprotective effects
Benefits Of Phenibut
One of the primary benefits of Phenibut powder is the ability to reduce anxious thoughts and stress levels. This benefit has been borne out by a number of clinical and lab-based studies.
Once Phenibut reaches your brain and central nervous system, it acts like GABA and targets those neurons or nerves which are overly excited and firing rapidly. Taking Phenibut crystals slows down the firing rate of these neurons so that they only respond to the most important stimuli.
GABA essentially tips the balance so that anxiety-producing stimuli are ignored with the intent of restoring normalized processing patterns. Users who take Phenibut powder say that it promotes relaxation and an overall sense of calm.
It seems to be especially popular among people with social anxiety and may even improve communication skills while lowering inhibitions. Students sometimes use this supplement to avoid test anxiety and they say it allows them to perform better under normally stressful conditions.
Clinical trials have found that Phenibut may also increase memory function. This makes Phenibut powder a nootropic or cognitive enhancer. It has been observed to boost short-term memory formation and also spatial memory.
In some reviews, users have said it may improve problem solving abilities, creativity, learning capacity and attention span. Still others report an overall improved ability to focus and concentrate without distraction.
Another very common application of Phenibut is for sleep issues. It may help to regulate proper sleep patterns and even increase the time spent in REM (i.e. the most restful and health promoting stage of sleep). This supplement may reduce insomniac bouts and has even been used for restless leg syndrome.
- Most effective supplements to improve mood
- Optimize levels of dopamine, serotonin and GABA
- Protect against stress and anxiety
Using Phenibut for Mood Disorders
In Russia Phenibut is considered to be a psychotropic drug and is regularly prescribed for post-traumatic stress disorder, anxiety, and insomnia. Those who suffer from stuttering and social anxiety might consider taking this nootropic.
Individuals with mild forms of anxiety and other mood disorders may find relief when using Phenibut. This supplement should be reserved for occasional use and you should not become reliant on its effects.
If you have a more serious condition that causes you to experience anxiety or depression, it is best to check with your doctor before starting a course of Phenibut usage.
Athletes are another group that can benefit from taking Phenibut due to the potential for faster muscle and strength growth. Finally, if you find that anxiety and stress make it difficult for you to focus at work or school, Phenibut may offer temporary relief.
Research on Phenibut powder is somewhat limited, and the majority is slighted dated studies from Russia in the 1960-80s. More current research still needs to be done to understand the full effects of Phenibut on conditions like anxiety. Even though it is used as a prescription drug in Russia, at this time, in the USA the FDA has not approved Phenibut as a drug to prevent or treat any conditions.
How to Take Phenibut Powder
While Phenibut comes in both capsule and powder form, the powder is much cheaper. It is absorbed into the system faster and begins working faster as well. You can use a set of microspoons or an electronic scale to measure out precise dosages.
The safe dosing range for Phenibut powder is between 200 and 1000 mg per day. Some might advocate taking more than this amount, but you should always try to use the smallest effective dosage when starting out.
Phenibut crystals have a rather long half-life, longer than most other Nootropics, so a single dose can remain more or less effective for an entire day.
Most people will take 500 mg in the evening or just before going to bed. If you are not sure how this supplement will affect you, make sure that your first dosage is taken in the latter half of the day as some will experience fatigue when using Phenibut.
Proper dosages depend on many factors including age, physiology, and the purpose for taking a supplement. The above recommendations are general guidelines only, and it is recommended that you speak with your doctor before beginning to take Phenibut. Your doctor will be able to determine the best dosage of Phenibut powder for your personal needs.
Even with proper dosage, it has been reported that tolerance can begin to form with continued usage of Phenibut. Some users say that tolerance can begin as soon as a week after beginning use. It is recommended to cycle usage to avoid tolerance issues. Some users have reported success with a one week on, two week off cycle, while others say they find the best results when they only take Phenibut as needed on an infrequent basis.
Phenibut FAA (Free Amino Acid)
Bulk Phenibut powder is typically sold in the crystalline salt form, where is it made into a stable chemical by reacting it with hydrochloric acid. This form will be labelled as Phenibut hydrochloride salt (HCl).
This compound is water soluble and easy to store and process, but can have a bitter taste and it can irritate mucous membranes and cause tooth damage.
Another newer form of this nootropic agent is the Free Amino Acid formulation, which contains 20% more Phenibut molecules compared to the same dosage of Phenibut HCL. It is essentially pure Phenibut with no impurities or other ingredients.
This form may require a slightly smaller dosage, but it gets converted into the hydrochloride salt form when it comes in contact with stomach acid. It is less soluble in water, has a milk bitter taste and has a close to neutral pH.
The main benefit of Phenibut FAA powder is that it does not need to be consumed orally in order to be effective. It is bio-available if taken sublingually or intranasally, which is the method of administration preferred by some users.
If you prefer to take Phenibut sublingually, then Phenibut Free Amino Acid powder is a better choice. According to some sources, via sublingual administration Phenibut needs to be taken at 1/3rd of the standard dosage.
Side Effects & Dangers
Phenibut powder can cause serious side effects if it is used in high dosages, taken for long periods of time or combined with other sedatives and GABAergic agents.
Although this nootropic agent is well-tolerated when used in accordance with the dosage guidelines there are some reported side effects. These can include increased sweating, drowsiness, reduced appetite, and restlessness.
More serious adverse effects can occur if using it in high dosages or consuming it with alcohol, benzodiazepines and other psychoactive substances. In extreme cases, it can result in unconsciousness, memory blackouts, impaired respiratory function, psychosis, hallucinations, hospitalizations and even death.
Do not mix phenibut powder with other sedatives and consulting with your doctor regarding drug and medication interactions and contraindications before taking this anxiolytic agent.
Because it is possible to develop a tolerance to Phenibut, it is strongly recommended that you do not take this supplement continuously for an extended period of time.
Some users who have persistently taken large doses of Phenibut to try and avoid tolerance end up experiencing serious withdrawal symptoms after they stop usage that can be very unpleasant.
Ideally, take Phenibut powder only as needed or cycle it to prevent your biochemistry from adjusting to the higher levels of GABA activity.
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- Shul'gina GI, Ziablitseva EA. [Effect of the GABA derivative phenibut on learning]. Vestn Ross Akad Med Nauk. 2005
- O'Connell CW, Schneir AB, Hwang JQ, Cantrell FL. Phenibut, the appearance of another potentially dangerous product in the United States. Am J Med. 2014
- Perfilova VN, Ivanova LB, Karamysheva VI, Borodin DD. [Effect of new phenibut salts on psychic and physical development of posterity in rats with experimental gestosis]. Eksp Klin Farmakol. 2012
- Dambrova M, Zvejniece L, Liepinsh E, Cirule H, Zharkova O, Veinberg G, Kalvinsh I. Comparative pharmacological activity of optical isomers of phenibut. Eur J Pharmacol. 2008
- Novikov VE, Chemodurova LN. [The effect of GABA-ergic agents on the blood electrolyte balance in acute craniocerebral trauma]. Eksp Klin Farmakol. 1992
Article last updated on: March 13th, 2018 by Nootriment
2 Comments
I am interested in purchasing some Phenibut. However, I am currently on the following perscription medications: citalopram hydrobromide 20mg, clonidine 2mg, prazosin 2mg, hydroxyzine HCL 50mg, and mirtazapine 30mg daily.
Which brand, type (economically), and daily dosage would you recomend I purchase? I won’t be using it on a daily basis.
Hey Robert,
It’s important to check with your doctor first before using Phenibut to prevent an unwanted interaction between this nootropic and the medications you are taking. We can’t provide medical information regarding specific dosage recommendations.