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What are the best phenibut stacks to take to promote anxiety relief and nootropic effects?
Some of the many uses for phenibut stacks include lifting the mood, enhancing social behaviors, supporting cognitive performance, improving sleep and promoting higher levels of human growth hormone secretions.
Although many of its purported benefits have not been validated in clinical trials, the use of Phenibut as an antianxiety nootropic supplement is gaining popularity.
This Russian anxiolytic agent has significant effects when used on its own but is sometimes stacked with other compounds depending on user goals. It may be stacked with Aniracetam, L-Theanine, Caffeine, Noopept, Sulbutiamine, Modafinil and more.
This article looks at some phenibut stacks used by college students, people in high-demand jobs, bodybuilders and other athletes, and those who use it recreationally.
Anxiety
Mood
Sleep & Insomnia- Powerful anxiolytic for stress reduction
- Stimulates GABA receptors & supports sleep
- Neuroprotective & supports cognitive function
Phenibut Stacks
Related Topics
- What is Phenibut?
- User Review
- Benefits and Uses
- Dosage Recommendations
- Effects & Mechanisms of Action
- Experience Reports
- Anti-Anxiety Effects
- Using Phenibut for Sleep
- How to Take
- Negative Side Effects
- Withdrawal Dangers
- Risks with Alcohol Combination
- Comparison to Picamilon
- Buying Phenibut Guide
- Using Bulk Powder
- Primaforce Phenibut Review
- SNS Phenibut XT Review
Phenibut is a nootropic agent that is purported to promote mood balance and relaxation without impairing memory or cognitive function at low doses.
It has antianxiety effects in many users and can help to quiet the mind during periods of high stress.
Some say that phenibut makes them feel like they have an alcohol buzz, but without the negative side effects commonly experienced with alcohol. [1]
Other users state that in high doses it makes them feel like they took benzodiazepines like Valium (alprazolam) or Xanax (diazepam). They say it causes the calming sedation without inhibiting their motivation to get up and accomplish tasks.
Using phenibut along with Xanax, Valium or other similar drugs is not recommended and can cause very serious side effects.
Used alone, phenibut powder is said to be helpful for reducing stress, deepening sleep, and improving cognitive performance by supporting concentration. A common dosage is between 250-1000 milligrams daily.
Phenibut can be added to any nootropic stack on days when a lot of stress or anxiety is expected.
How to Use in a Stack
“Stacking” refers to combining multiple substances together in order to induce synergistic effects or promote a wider range of effects. Some people use stacks to increase the effectiveness of individual nootropic agents or to counteract certain negative effects.
Phenibut stacks may be used to increase the relaxation-inducing effects or to promote greater energy and alertness while still benefitting from the calmness of mind.
Mixing phenibut with some substances can be dangerous, such as benzodiazepine drugs, Gabaergic agents and drinking alcohol in excess. [2]
However, there are other substances that it can be stacked with that are purported to promote positive results and have a low risk of adverse effects.
Some dietary supplements that are used in phenibut stacks include:
- The amino acid L-tryptophan, which is the precursor to a brain chemical called serotonin;
- The amino acid L-theanine found in green tea (Camellia sinensis);
- German Chamomile (Matricaria chamomilla);
- Cannabis sativa and Cannabis indica (Weed, Marijuana);
- Ashwagandha (Withania somnifera);
- Holy Basil (Ocimum tenuiflorum);
- Lemon Balm (Melissa officinalis);
- Kava-Kava (Piper methysticum);
- Valerian (Valeriana officinalis);
Some stacks for memory, athletic recovery, mood, and anxiety are listed below. First it is important to understand how this compound works and how it should be used.
- Powerful anxiolytic for stress reduction
- Improves sleep and may reduce insomnia
- Neuroprotective and cardioprotective effects
How It Works
To understand how phenibut works, it is necessary to know a bit about brain chemicals called neurotransmitters.
Neurotransmitters are signaling chemicals that nerves (neurons) use to communicate with one another to facilitate processes if the CNS (central nervous system).
The CNS is comprised of the brain and spinal cord. Neurotransmitters can be either excitatory or inhibitory to nerves in the CNS.
The primary inhibitory neurotransmitter in the human brain is called GABA (gamma-aminobutyric acid).
Phenibut’s scientific name is beta-phenyl-gamma-aminobutyric acid, which indicates that it is a phenylated version of the GABA molecule.
In the brain GABA plays a role in regulating mood, to reduce anxiety and stress, improve sleep, and modulate muscle tone.
Synthetic GABA supplements are available for those who desire to increase their levels for emotional balance or promoting calmness. However, synthetic GABA is not well able to cross the blood-brain barrier (BBB) and may not have potent neurological effects..
Phenibut is a derivative of GABA that has similar effects in the CNS and can bind to the same classes of neural receptors. Its phenylated molecular structure allows it to cross the blood-brain barrier more easily, which means it demonstrates greater activity following oral ingestion.
Many users report reduce feelings of over-stimulation, a quieting of racing thoughts, increased mental clarity, decreased social inhibitions, increased confidence, prosocial behavior, and improved sleep.
According to Corpina, “GABA opens up channels in the neurons, decreases the function of other neurotransmitters, and reduces collective anxiety in the neuron.”
Scientists are unsure about how phenibut works precisely. However, it is thought to affect GABA, dopamine and possibly serotonin and HGH (human growth hormone) levels.
Anxiety Stacks
Phenibut is best-known as an anxiolytic agent with fear-reducing properties. Many people use it to help them overcome social awkwardness, combat panic attacks and to promote emotional steadiness.
Some people use phenibut in nootropic stacks to help them feel better about making public speeches. Others use it to gain enough confidence to ask someone out on a date.
Many people reserve their usage for nights when they want to go out and party. When used responsibly in this manner, it is said to induce a relaxing, casual, carefree and prosocial mood.
According to user testimonials, this product can make music sound better and can make it easier to have conversations with people without over-thinking what you are trying to say.
For improving mood and reducing anxiety, some people recommend a phenibut stack with an herbal supplement called Bacopa monnieri and a phospholipid compound called phosphatidylserine.
Another option is to add it to the classic nootropic stack of L-Theanine and Caffeine. This stack is purported to promote a balance state of mental calm and focus.
Aniracetam is another anxiolytic nootropic that has a different mechanism of action. It is reported to have synergistic benefits when used with this GABAergic compound.
Note that Phenibut has a longer duration of effects than Aniracetam. Typically, it will be taken once a day while the anxiolytic racetam will be taken two to three times per day.
Noopept also exhibit anxiolytic effects in some users, but not all. It is described as having mood-lifting effects by some individuals.
Phenibut was previously used as the active ingredient in a dietary supplement called MRM Relax-All along with other herbs and nutrients that promote feelings of well-being.
Other ingredients found in this product include L-Tryptophan, Jujube extract, Chamomile, Lemon balm, Valerian root, Rafuma leaf extract, Ashwagandha, Inositol and GABA
Bodybuilding Stacks
Because GABA is known to affect muscle tone, and phenibut is a phenylated GABA derivative, some bodybuilders and weightlifters use this nootropic in stacks to help them perform, heal and grow better.
Research shows that during periods of deep sleep, the body produces more human growth hormone. GABA and other related supplements are sometimes used to induce deep, restful sleep and support higher secretions of HGH.
While this has not been studied in any research trials, users claim that taking Phenibut may help athletes recover from strenuous workouts faster.
Some athletes use this product stacked with other supplements that support human growth hormone levels, such as mucuna pruriens and Alpha GPC.
- Most effective supplements to improve mood
- Optimize levels of dopamine, serotonin and GABA
- Protect against stress and anxiety
Nootropic Stacks
Other substances that have been stacked with phenibut to increase motivation include Phenylpiracetam, Sulbutiamine, and Pramiracetam.
Modafinil and Adrafinil are used are some stacks to enhance cognitive performance and brighten mood. This stack is described by users as boosting focus and energy levels.
For supporting memory formation and recall, Phenibut has been stacked with 30 milligrams of Noopept. It may also be stacked with Piracetam or Oxiracetam.
It has bene used with a derivative of DMAE (dimethylaminoethanol) called centrophenoxine. This combination is purported to support cognitive performance as well as brain health.
One online source states that taking a nootropic supplement called Alpha Brain along with phenibut can increase activity at GABA-B receptors and helps lower feelings of anxiousness more than it does alone. Alpha Brain has also be used to reduce symptoms of any phenibut hangover experienced.
Some people also combine phenibut with a different GABA derivative called GABON (gamibetal, buxamin).
This stack is claimed to help some users with mood balance and cognitive function. However, there is no scientific research available that can be used to evaluate this claim.
Stacking Phenibut and Cannabis
Cannabis sativa and Cannabis indica strains of marijuana plants contain numerous bioactive chemicals and nutrients that make this plant one of the world’s most well-known and widely-respected natural medicines.
Many people smoke, vaporizer, eat or otherwise administer Cannabis to brighten moods, relieve pain, fight depression, and much more.
Phenibut is sometimes mixed with Cannabis to heighten the effects of both. This stack has not been studied in research settings, so the only information available about its effects comes from anecdotal evidence.
Using with Alcohol
Like phenibut and benzodiazepine drugs, alcohol is a GABA receptor agonist. Mixing these substances can be dangerous and can cause over-stimulation of GABAergic receptors.
Alcohol is harmful when consumed in large quantities and can contribute to loss of consciousness, impaired thinking and physical movement, loss of judgement, and more serious physiological side effects.
Be careful consuming phenibut with alcohol. Some users report that this combination results in feeling more intoxicated quickly and finding it difficult to gauge how drunk you are.
While some college students claim that phenibut is a cheaper, safer and less-hangover-prone substitute for alcohol, others claim it makes them resistant to the effects of alcohol; causing them to overconsume.
Conclusion
Many people use phenibut stacks to help them calm down, increase their sense of well-being and feel more comfortable in social settings.
Some users report nootropic effects from taking it as a smart drug while others say it does not significantly improve cognitive function and may interfere with thinking.
There is potential for harmful side effects, tolerance, withdrawal symptoms, and addiction if taking this substance at high dosages or using it for long periods of time. Use it sparingly and be sure to cycle usage on and off regularly.
There is are a number of phenibut stacks possible. As with other nootropic stacks, you will have to experiment with different stacks to find which work well for your purposes.
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Article last updated on: July 10th, 2018 by Nootriment