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Picamilon is a nootropic supplement known for its ability to reduce anxiety while at the same time it is works to enhance a person’s memory and ability to focus.
It has become popular among individuals who want to lessen their susceptibility to developing anxious feelings without causing sedation or slowing down mental performance.
Although it may not be as widely known as other smart drugs, it is a useful supplement to have in your smart drug toolbox.
Picamilon is an odorless white crystalline powder which is readily soluble in water. You can find Picamilon 150 mg tablets at select nootropics vendors or purchase bulk power for significant discounts.
Mood
Anxiety
Sleep- Consists of GABA & Niacin
- Stimulates GABA receptors in the brain
- Promotes mood, sleep & relaxation
Why Use Picamilon
Related Topics
Picamilon is a source of GABA which is known to have a number of positive effects when it reaches the brain.
GABA supplements are unable to effectively penetrate the blood-brain barrier.
In an effort to develop a supplement which could enable GABA to pass through this barrier, researchers in the USSR combined GABA with Niacin, a compound which is able to penetrate the blood-brain barrier more easily, and can carry GABA along with it. The researchers succeeded in the early 1960s.
Synthesized from a combination of Niacin (Vitamin B3) and GABA, Picamilon delivers GABA across the blood brain barrier where it becomes available for use by the brain. Once in the brain, Niacin acts as a vasodilator, allowing more oxygen to flow, via the blood, to the brain.
GABA works as an inhibitor to calm neurons which are firing rapidly or uncontrollably. People with depression or anxiety disorders have been shown to have low levels of GABA in their brains.
Picamilon’s side effects, if experienced, are mostly mild though there have been rare cases of allergic reaction and serious skin rash.
Effects and Uses
Picamilon tablets enhance concentration, attention, cognition, motivation, intelligence, planning and memory which makes it effective for ADHD treatment. In studies, it was shown to even reduce impulsiveness of actions, thus resulting in more appropriate decision making. Overall, Picamilon 150 mg has a positive effect on all cognitive function.
In Russia, where Picamilon was developed in the mid-twentieth century, it is prescribed for the following illnesses: cerebral blood flow problems, vasoneurosis, depression, asthenia, acute alcohol intoxication, senile psychosis, migraine, brain infections, primary open glaucoma and craniocerebral trauma.
Dosing
Picamilon tablets are available starting at 50mg and go up from there with the best-selling option being the 150 mg pills.
It is recommended for new users to begin at the 50mg dose in order to determine how this supplement works with your system.
Though many people find they do not need to take doses higher than 50mg, some users may require a higher dose in order to experience the benefits.
Regardless of the dose you take, Picamilon is known to build tolerance, thus it should be cycled with regularity in order to keep your brain sensitive to the effects of this supplement.
As with many medications or supplements, the higher the dose, the more likely it is that tolerance will develop more quickly, thus the need for frequent cycling becomes even more important.
Picamilon 150mg Tablets
If taking Picamilon in 150mg doses, user reviews recommend you not exceed two doses each day. It is possible, and recommended, to use Picamilon on an “as needed” basis, rather than as part of your daily regimen. This will help to maintain your brain’s sensitivity to the supplement and ward off tolerance for as long as possible.
If you choose to make it part of your regular regimen, then consider cycling off at least 3 days per week in an irregular pattern to help avoid developing tolerance. Do not exceed 4 weeks of continuous use without taking at least a 2 week break.
Side Effects
The most common side effects were quite mild and included tingling, nausea and headache. If experiencing headache, consider adding 250-350mg of Citicoline or Alpha GPC to your stack. This may remedy the problem. All of these effects quickly subsided when the patient stopped taking the supplement.
More serious side effects, though considered quite rare, include serious skin reactions requiring hospitalization and allergic reactions.
Picamilon should only be taken by adults as it is untested in children and the long-term effects are unknown. Pregnant or lactating women should not take Picamilon. Check with your doctor to make sure Picamilon will not adversely interact with any medications or supplements you may currently be taking.
Review of Picamilon Tablets
Although most people are able to experience the benefits of Picamilon at lower doses, some individuals may require a 150mg dose in order for this supplement to be effective. Those with a GABA deficiency will benefit most from supplementation with this nootropic.
Picamilon is known to build tolerance. Taking Picamilon 150mg tablets are best when used on an “as needed” basis in order to keep their effectiveness at an optimal level.
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- VishnevskiÄ EL, Guseva NB. [Validation of the treatment of the neurogenic bladder in children with myelodysplasia using pikamilon]. Urol Nefrol (Mosk). 1998
- Dorofeev BF, Kholodov LE. [Pikamilon pharmacokinetics in animals]. Farmakol Toksikol. 1991
- Akopian VP, Balian LS, Avetisian NA. [The effect of hypokinesia on depression and on the central GABA-A receptor complexes in the rat brain]. Eksp Klin Farmakol. 2006
- Shymans'kyÄ IO, Kuchmerov'ska TM, Donchenko HV, VelykyÄ MM, Klymenko AP, Palyvoda OM, Kuchmerovs'kyÄ MO. [Oxidative stress correction by nicotinamide and nicotynol-GABA in diabetic neuropathy]. Ukr Biokhim Zh (1999). 2002
Article last updated on: March 13th, 2018 by Nootriment