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Picamilon is a synthesized combination of Niacin (Vitamin B3) and GABA. Canadian nootropic users find Picamilon to be useful for reducing anxiety and for enhancing cognitive functions such as memory and concentration.
Niacin acts as a vasodilator, allowing more oxygen to flow, via the blood, to the brain. GABA works as an inhibitor to calm nerves which may be firing in a continuous or uncontrollable fashion.
People with depression or anxiety disorders have been thought to have low levels of GABA in their brains.
Where can you buy Picamilon in Canada and do you need a prescription to get this supplement?
Mood
Anxiety
Sleep- Consists of GABA & Niacin
- Stimulates GABA receptors in the brain
- Promotes mood, sleep & relaxation
How It Works
Related Topics
Anxiety is thought to be produced when too many of the neurons in the brain are firing in rapid succession all at once.
GABA is a neurotransmitter which can calm the excited neurons, allowing the person to experience a less anxious state. As excitation slows, the result is an overall feeling of calm and relaxation.
This may be why many users of Picamilon also report experiencing a slight mood elevation in addition to decreased anxiety. GABA is also used in the brain to help nerves and neurons to efficiently communicate with one another. The cognitive enhancing benefits of Picamilon are partly due to this GABA function.
The problem with GABA supplementation arises because GABA, by itself, is unable to penetrate the blood-brain barrier to a degree which would allow any beneficial effect to be experienced. Taking GABA orally is nearly useless because of this major hurdle.
The GABA your brain is currently using is made within your brain cells by converting other ingredients into GABA. Taking Gamma-Aminobutyric Acid (GABA) directly, by itself, cannot increase levels of this neurotransmitter in your brain.
In 1961, researchers at a scientific research institute in the USSR set about developing a means capable of delivering GABA to the brain. To this end, they combined it with Niacin, a compound which is able to penetrate the blood-brain barrier more easily, and is capable of carrying GABA along with it. The result was the development of the drug Picamilon or Pikamilon.
In addition to delivering GABA to the brain, Niacin (B3) dilates blood passages which allows more oxygen to pass to, and be used by, the brain. At the same time, the GABA is used directly to soothe excited neurons and to create more cogent communication between the neurotransmitters.
Users say that taking Picamilon powder results in relief from stress and mental tension without the unwanted effects of sedation or slower cognition. Using Picamilon can actually improve energy and focus while keeping mood and anxiety levels in balance.
Buying Picamilon in Canada
Although there have been Canadian suppliers for Picamilon in the past, it can be difficult to locate. Many Canadian residents find themselves ordering their supplies online from stores within the United States. Canadian residents are allowed to import Picamilon supplements for personal use without any special requirements or licenses.
We recommend researching online and comparing reputable stores for price and quality, and also for shipping cost and expedience. Picamilon is sold in bulk powder or capsule form. The difference in cost between the two can be significant, with capsules being priced at 2x – 3x that of bulk powder.
If you find you like the effects of Picamilon and intend to add it to your regular stack, it may be worthwhile to consider buying a small capsule machine and making your own capsules at a fraction of the cost.
Dosage
Dosage for Picamilon varies from user to user somewhere between 50mg to 400mg. We strongly recommend beginning with 50mg and allowing the effect to be experienced.
Most people who use Picamilon for mood boosting and anxiety relief report using between 50mg-100mg per day. Those using Picamilon for a boost in energy report dosing between 100mg-200mg.
It is important to start at the low end with Picamilon to ascertain if Picamilon will work with your system or not.
Some people report no effect whatsoever when supplementing with Picamilon. Research has not discovered why this occurs but it may be because they already have an effective level of GABA in the brain and, thus, supplementation doesn’t produce a marked effect in their mental or physical state.
Starting at the lowest dose also allows the user to monitor for side effects. If you experience headache, tingling or nausea, stop taking the supplement. If side effects persist, consult with your doctor. More serious side effects, though rare, have been reported including allergic reactions and skin rashes. If you suspect either of these, seek medical attention promptly.
Picamilon should not be taken if you are already taking medications which lower your blood pressure.
Summary
Finding Picamilon in Canada can be difficult as few supplement retailers will carry it in stock. In Canada, most Picamilon users choose to order their supply from nootropic or nutritional stores located in the United States.
Choose a reputable store whose products are clearly displayed with Certificates of Analysis and whom other users have reviewed positively for both quality and shipping. Canadian residents are free to import Picamilon for their own personal use or research.
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- Akopian VP, Balian LS, Zakarian NA. [Effect of nootropes on quantitative changes in the rat cerebral cortex GABA(A) receptor complexes under experimental hypokinesia conditions]. Eksp Klin Farmakol. 2010
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- VishnevskiÄ EL, Guseva NB. [Validation of the treatment of the neurogenic bladder in children with myelodysplasia using pikamilon]. Urol Nefrol (Mosk). 1998
Article last updated on: March 13th, 2018 by Nootriment
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This post does not reflect its title “How to Get this Anti-Anxiety Supplement”.